Huntingtin's function in axonal transport is conserved in Drosophila melanogaster
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Potential function for the Huntingtin protein as a scaffold for selective autophagy.Huntingtin Is Required for Neural But Not Cardiac/Pancreatic Progenitor Differentiation of Mouse Embryonic Stem Cells In vitro.Huntingtin differentially regulates the axonal transport of a sub-set of Rab-containing vesicles in vivo.Self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport.Huntingtin proteolysis releases non-polyQ fragments that cause toxicity through dynamin 1 dysregulation.Drosophila models reveal novel insights into mechanisms underlying neurodegeneration.Challenges of Huntington's disease and quest for therapeutic biomarkers.Lissencephaly-1 dependent axonal retrograde transport of L1-type CAM Neuroglian in the adult drosophila central nervous system.Exosomes and Homeostatic Synaptic Plasticity Are Linked to Each other and to Huntington's, Parkinson's, and Other Neurodegenerative Diseases by Database-Enabled Analyses of Comprehensively Curated Datasets.Characterization of axonal transport defects in Drosophila Huntingtin mutants.Role of context in RNA structure: flanking sequences reconfigure CAG motif folding in huntingtin exon 1 transcripts.Live imaging of axonal transport in Drosophila pupal brain explants.Loss of Huntingtin stimulates capture of retrograde dense-core vesicles to increase synaptic neuropeptide stores.RNA Aptamers Rescue Mitochondrial Dysfunction in a Yeast Model of Huntington’s Disease.The Tiny for the Biggest Answers in Huntington's Disease
P2860
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P2860
Huntingtin's function in axonal transport is conserved in Drosophila melanogaster
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Huntingtin's function in axonal transport is conserved in Drosophila melanogaster
@ast
Huntingtin's function in axonal transport is conserved in Drosophila melanogaster
@en
Huntingtin's function in axonal transport is conserved in Drosophila melanogaster
@nl
type
label
Huntingtin's function in axonal transport is conserved in Drosophila melanogaster
@ast
Huntingtin's function in axonal transport is conserved in Drosophila melanogaster
@en
Huntingtin's function in axonal transport is conserved in Drosophila melanogaster
@nl
prefLabel
Huntingtin's function in axonal transport is conserved in Drosophila melanogaster
@ast
Huntingtin's function in axonal transport is conserved in Drosophila melanogaster
@en
Huntingtin's function in axonal transport is conserved in Drosophila melanogaster
@nl
P2860
P3181
P1433
P1476
Huntingtin's function in axonal transport is conserved in Drosophila melanogaster
@en
P2093
Maria-Victoria Hinckelmann
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0060162
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P577
2013-03-28T00:00:00Z