The cohesin complex is required for the DNA damage-induced G2/M checkpoint in mammalian cells
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The ancient and evolving roles of cohesin in gene expression and DNA repairA new thermosensitive smc-3 allele reveals involvement of cohesin in homologous recombination in C. elegansCohesin rings devoid of Scc3 and Pds5 maintain their stable association with the DNACohesin: functions beyond sister chromatid cohesionHinokitiol induces DNA damage and autophagy followed by cell cycle arrest and senescence in gefitinib-resistant lung adenocarcinoma cellsDisruption of CHTF18 causes defective meiotic recombination in male miceReduction of Nipbl impairs cohesin loading locally and affects transcription but not cohesion-dependent functions in a mouse model of Cornelia de Lange SyndromeA Surveillance Mechanism Ensures Repair of DNA Lesions during Zygotic ReprogrammingDNA IR-Double Strand Breaks (DSBs) and cellular response via ATMDifferential cohesin loading marks paired and unpaired regions of platypus sex chromosomes at prophase I.Cohesin protects genes against γH2AX Induced by DNA double-strand breaks.Phosphorylation of chromosome core components may serve as axis marks for the status of chromosomal events during mammalian meiosisThe synergistic cytotoxicity of clofarabine, fludarabine and busulfan in AML cells involves ATM pathway activation and chromatin remodelingRecurrent mutations in multiple components of the cohesin complex in myeloid neoplasms.Phosphorylation of SMC1 by ATR is required for desferrioxamine (DFO)-induced apoptosis.Blood-based detection of radiation exposure in humans based on novel phospho-Smc1 ELISARole of SMC1A overexpression as a predictor of poor prognosis in late stage colorectal cancer.SMCHD1 accumulates at DNA damage sites and facilitates the repair of DNA double-strand breaksThe AtRAD21.1 and AtRAD21.3 Arabidopsis cohesins play a synergistic role in somatic DNA double strand break damage repair.ATRX contributes to epigenetic asymmetry and silencing of major satellite transcripts in the maternal genome of the mouse embryoSororin is a master regulator of sister chromatid cohesion and separationRAD21 mutations cause a human cohesinopathyIndependent mechanisms recruit the cohesin loader protein NIPBL to sites of DNA damage.DNA damage-induced metaphase I arrest is mediated by the spindle assembly checkpoint and maternal age.Proteomic profile identifies dysregulated pathways in Cornelia de Lange syndrome cells with distinct mutations in SMC1A and SMC3 genes.Reduced cohesin destabilizes high-level gene amplification by disrupting pre-replication complex bindings in human cancers with chromosomal instability.Connecting chromatin modifying factors to DNA damage response.Cajal bodies are linked to genome conformationA regulatory role for the cohesin loader NIPBL in nonhomologous end joining during immunoglobulin class switch recombination.The cohesin complex regulates immunoglobulin class switch recombination.Whole Chromosome Instability induces senescence and promotes SASP.Spindle assembly checkpoint of oocytes depends on a kinetochore structure determined by cohesin in meiosis I.Distinct functions of human cohesin-SA1 and cohesin-SA2 in double-strand break repairRAD21 cohesin overexpression is a prognostic and predictive marker exacerbating poor prognosis in KRAS mutant colorectal carcinomas.Cohesin: a critical chromatin organizer in mammalian gene regulationThe Smc complexes in DNA damage response.Diverse developmental disorders from the one ring: distinct molecular pathways underlie the cohesinopathies.Genome stability: What we have learned from cohesinopathies.ASXL1 interacts with the cohesin complex to maintain chromatid separation and gene expression for normal hematopoiesis.siRNA-mediated knockdown of SMC1A expression suppresses the proliferation of glioblastoma cells.
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P2860
The cohesin complex is required for the DNA damage-induced G2/M checkpoint in mammalian cells
description
2009 nî lūn-bûn
@nan
2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
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2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
The cohesin complex is require ...... checkpoint in mammalian cells
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The cohesin complex is require ...... checkpoint in mammalian cells
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The cohesin complex is require ...... checkpoint in mammalian cells
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The cohesin complex is require ...... checkpoint in mammalian cells
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type
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The cohesin complex is require ...... checkpoint in mammalian cells
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The cohesin complex is require ...... checkpoint in mammalian cells
@en
The cohesin complex is require ...... checkpoint in mammalian cells
@en-gb
The cohesin complex is require ...... checkpoint in mammalian cells
@nl
prefLabel
The cohesin complex is require ...... checkpoint in mammalian cells
@ast
The cohesin complex is require ...... checkpoint in mammalian cells
@en
The cohesin complex is require ...... checkpoint in mammalian cells
@en-gb
The cohesin complex is require ...... checkpoint in mammalian cells
@nl
P2860
P3181
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The cohesin complex is require ...... checkpoint in mammalian cells
@en
P2093
Erwan Watrin
P2860
P304
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10.1038/EMBOJ.2009.202
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P577
2009-09-02T00:00:00Z