Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms.
about
Cytogenetic and molecular abnormalities in chronic myelomonocytic leukemiaThe biology of pediatric acute megakaryoblastic leukemiaSequencing Overview of Ewing Sarcoma: A Journey across Genomic, Epigenomic and Transcriptomic LandscapesCohesin mutations in myeloid malignancies: underlying mechanismsDose-dependent role of the cohesin complex in normal and malignant hematopoiesis.Emerging concepts of epigenetic dysregulation in hematological malignanciesEpigenetics in Cancer: A Hematological PerspectiveMutant Cohesin in Premature Ovarian FailureCohesion promotes nucleolar structure and functionDefective sister chromatid cohesion is synthetically lethal with impaired APC/C function.Combining gene mutation with gene expression data improves outcome prediction in myelodysplastic syndromes.Genetic abnormalities in myelodysplasia and secondary acute myeloid leukemia: impact on outcome of stem cell transplantationComprehensive mutational profiling of core binding factor acute myeloid leukemia.The genetics of myelodysplastic syndrome: from clonal haematopoiesis to secondary leukaemiaThe genomic landscape of the Ewing Sarcoma family of tumors reveals recurrent STAG2 mutation.The genomic landscape of core-binding factor acute myeloid leukemiasGlioblastoma cells containing mutations in the cohesin component STAG2 are sensitive to PARP inhibitionOverexpression and constitutive nuclear localization of cohesin protease Separase protein correlates with high incidence of relapse and reduced overall survival in glioblastoma multiformeGenetic alterations of the cohesin complex genes in myeloid malignancies.Cohesin gene mutations in tumorigenesis: from discovery to clinical significanceSTAG2 promotes error correction in mitosis by regulating kinetochore-microtubule attachments.Sororin pre-mRNA splicing is required for proper sister chromatid cohesion in human cells.Pan-cancer network analysis identifies combinations of rare somatic mutations across pathways and protein complexesGenomic landscape of Ewing sarcoma defines an aggressive subtype with co-association of STAG2 and TP53 mutations.Mutations in RAD21 disrupt regulation of APOB in patients with chronic intestinal pseudo-obstructionGermline gain-of-function mutations in AFF4 cause a developmental syndrome functionally linking the super elongation complex and cohesinThe contribution of cohesin-SA1 to gene expression and chromatin architecture in two murine tissues.Recent advances in myelodysplastic syndromes: Molecular pathogenesis and its implications for targeted therapies.Mutational spectrum of adult T-ALLMEMCover: integrated analysis of mutual exclusivity and functional network reveals dysregulated pathways across multiple cancer typesPathway Analysis Based on a Genome-Wide Association Study of Polycystic Ovary SyndromeIntact Cohesion, Anaphase, and Chromosome Segregation in Human Cells Harboring Tumor-Derived Mutations in STAG2.Cohesin loss alters adult hematopoietic stem cell homeostasis, leading to myeloproliferative neoplasmsProfiling of somatic mutations in acute myeloid leukemia with FLT3-ITD at diagnosis and relapse.Leukemia-Associated Cohesin Mutants Dominantly Enforce Stem Cell Programs and Impair Human Hematopoietic Progenitor Differentiation.MicroRNA biomarker identification for pediatric acute myeloid leukemia based on a novel bioinformatics model.DriverDBv2: a database for human cancer driver gene research.Digging deep into "dirty" drugs - modulation of the methylation machinery.Reduced cohesin destabilizes high-level gene amplification by disrupting pre-replication complex bindings in human cancers with chromosomal instability.Mutation allele burden remains unchanged in chronic myelomonocytic leukaemia responding to hypomethylating agents.
P2860
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P1343
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P2860
Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms.
description
2013 nî lūn-bûn
@nan
2013 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms.
@ast
Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms.
@en
Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms.
@nl
type
label
Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms.
@ast
Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms.
@en
Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms.
@nl
prefLabel
Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms.
@ast
Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms.
@en
Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms.
@nl
P2093
P2860
P4510
P50
P356
P1433
P1476
Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms.
@en
P2093
Aiko Nishimoto
Aiko Sato-Otsubo
Daniel Nowak
Florian Nolte
Genta Nagae
H Phillip Koeffler
Hiraku Mori
Hiroko Tanaka
Hiromitsu Nakauchi
P2860
P2888
P304
P356
10.1038/NG.2731
P407
P50
P577
2013-08-18T00:00:00Z