The chromatin remodelling factor BRG1 is a novel binding partner of the tumor suppressor p16INK4a
about
SS18 together with animal-specific factors defines human BAF-type SWI/SNF complexesHistone Modifications, Modifiers and Readers in Melanoma Resistance to Targeted and Immune TherapyBrg1 loss attenuates aberrant wnt-signalling and prevents wnt-dependent tumourigenesis in the murine small intestineHeterogeneous SWI/SNF chromatin remodeling complexes promote expression of microphthalmia-associated transcription factor target genes in melanoma.BRG1 promotes hepatocarcinogenesis by regulating proliferation and invasivenessSWI/SNF chromatin remodeling enzymes in melanocyte differentiation and melanoma.Brg-1 mediates the constitutive and fenretinide-induced expression of SPARC in mammary carcinoma cells via its interaction with transcription factor Sp1.Human parvovirus B19 causes cell cycle arrest of human erythroid progenitors via deregulation of the E2F family of transcription factorsThe BRG1 chromatin remodeler protects against ovarian cysts, uterine tumors, and mammary tumors in a lineage-specific manner.The p16(INK4A) tumor suppressor regulates cellular oxidative stressNovel multiple markers to distinguish melanoma from dysplastic nevi.MITF-independent pro-survival role of BRG1-containing SWI/SNF complex in melanoma cells.Modulation of extracellular matrix/adhesion molecule expression by BRG1 is associated with increased melanoma invasiveness.Functional epigenetics approach identifies BRM/SMARCA2 as a critical synthetic lethal target in BRG1-deficient cancers.SWI/SNF complexes are required for full activation of the DNA-damage response.SWItching on the transcriptional circuitry in melanoma.The chromatin remodeling and mRNA splicing functions of the Brahma (SWI/SNF) complex are mediated by the SNR1/SNF5 regulatory subunit.Combining BET and HDAC inhibitors synergistically induces apoptosis of melanoma and suppresses AKT and YAP signaling.HBP1-mediated Regulation of p21 Protein through the Mdm2/p53 and TCF4/EZH2 Pathways and Its Impact on Cell Senescence and Tumorigenesis.Brahma-related gene 1 induces apoptosis in a p53-dependent manner in human rheumatoid fibroblast-like synoviocyte MH7ARegulatory mechanisms of tumor suppressor P16(INK4A) and their relevance to cancer.Chromatin regulators with tumor suppressor properties and their alterations in human cancers.Beyond Mutations: Additional Mechanisms and Implications of SWI/SNF Complex Inactivation.Histone variants and melanoma: facts and hypotheses.BRM and BRG1 subunits of the SWI/SNF chromatin remodelling complex are downregulated upon progression of benign skin lesions into invasive tumours.Brg1 is required for stem cell maintenance in the murine intestinal epithelium in a tissue-specific manner.Use of clinical next-generation sequencing to identify melanomas harboring SMARCB1 mutations.Multiple functions of Kip-related protein5 connect endoreduplication and cell elongation.
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P2860
The chromatin remodelling factor BRG1 is a novel binding partner of the tumor suppressor p16INK4a
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2009 nî lūn-bûn
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2009 թուականին հրատարակուած գիտական յօդուած
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2009 թվականին հրատարակված գիտական հոդված
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2009年の論文
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2009年論文
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2009年論文
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2009年論文
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2009年論文
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2009年論文
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2009年论文
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The chromatin remodelling fact ...... the tumor suppressor p16INK4a
@ast
The chromatin remodelling fact ...... the tumor suppressor p16INK4a
@en
The chromatin remodelling fact ...... the tumor suppressor p16INK4a
@en-gb
The chromatin remodelling fact ...... the tumor suppressor p16INK4a
@nl
type
label
The chromatin remodelling fact ...... the tumor suppressor p16INK4a
@ast
The chromatin remodelling fact ...... the tumor suppressor p16INK4a
@en
The chromatin remodelling fact ...... the tumor suppressor p16INK4a
@en-gb
The chromatin remodelling fact ...... the tumor suppressor p16INK4a
@nl
prefLabel
The chromatin remodelling fact ...... the tumor suppressor p16INK4a
@ast
The chromatin remodelling fact ...... the tumor suppressor p16INK4a
@en
The chromatin remodelling fact ...... the tumor suppressor p16INK4a
@en-gb
The chromatin remodelling fact ...... the tumor suppressor p16INK4a
@nl
P2093
P2860
P50
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P356
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The chromatin remodelling fact ...... the tumor suppressor p16INK4a
@en
P2093
David N Reisman
Eve Diefenbach
Lyndee L Scurr
Menno K Dijkstra
Monika Frausto
Sebastian Haferkamp
P2860
P2888
P3181
P356
10.1186/1476-4598-8-4
P407
P577
2009-01-01T00:00:00Z
P5875
P6179
1007988057