RNF168, a new RING finger, MIU-containing protein that modifies chromatin by ubiquitination of histones H2A and H2AX
about
UMI, a novel RNF168 ubiquitin binding domain involved in the DNA damage signaling pathwayDynamics of DNA damage response proteins at DNA breaks: a focus on protein modificationsWriters, Readers, and Erasers of Histone Ubiquitylation in DNA Double-Strand Break RepairA Novel Aspect of Tumorigenesis-BMI1 Functions in Regulating DNA Damage ResponseFine-tuning the ubiquitin code at DNA double-strand breaks: deubiquitinating enzymes at workUEV-1 is an ubiquitin-conjugating enzyme variant that regulates glutamate receptor trafficking in C. elegans neuronsHistone ubiquitylation and its roles in transcription and DNA damage responseA single MIU motif of MINDY-1 recognizes K48-linked polyubiquitin chainsHistone H2A and H2B are monoubiquitinated at AID-targeted loci.Rnf8 deficiency impairs class switch recombination, spermatogenesis, and genomic integrity and predisposes for cancer.An RNF168 fragment defective for focal accumulation at DNA damage is proficient for inhibition of homologous recombination in BRCA1 deficient cells.Genomic instability, defective spermatogenesis, immunodeficiency, and cancer in a mouse model of the RIDDLE syndromeTight regulation of ubiquitin-mediated DNA damage response by USP3 preserves the functional integrity of hematopoietic stem cells.DNA double-strand break signaling and human disorders.Critical roles of ring finger protein RNF8 in replication stress responses.Bora downregulation results in radioresistance by promoting repair of double strand breaks.Identification of RNF168 as a PML nuclear body regulatorA dual role for K63-linked ubiquitin chains in multivesicular body biogenesis and cargo sortingUSP7 deubiquitinase promotes ubiquitin-dependent DNA damage signaling by stabilizing RNF168.Ubiquitin-H2AX fusions render 53BP1 recruitment to DNA damage sites independent of RNF8 or RNF168Dynamic Changes in Occupancy of Histone Variant H2A.Z during Induced Somatic Cell Reprogramming.RING finger nuclear factor RNF168 is important for defects in homologous recombination caused by loss of the breast cancer susceptibility factor BRCA1Viral E3 ubiquitin ligase-mediated degradation of a cellular E3: viral mimicry of a cellular phosphorylation mark targets the RNF8 FHA domain.The spatial and temporal organization of ubiquitin networksIt takes two to tango: Ubiquitin and SUMO in the DNA damage response.The ubiquitin specific protease USP34 promotes ubiquitin signaling at DNA double-strand breaksStructural mechanisms underlying signaling in the cellular response to DNA double strand breaks.A role for the p53 tumour suppressor in regulating the balance between homologous recombination and non-homologous end joining.Chronic oxidative stress promotes H2AX protein degradation and enhances chemosensitivity in breast cancer patients.Role of ubiquitination in meiotic recombination repair.The BRCA1 ubiquitin ligase and homologous recombination repair.The ubiquitin- and SUMO-dependent signaling response to DNA double-strand breaks.Chromatin and the DNA damage response: the cancer connection.The emerging role of Polycomb repressors in the response to DNA damage.DNA damage repair and bacterial pathogensThe role of ubiquitin-binding domains in human pathophysiology.Programmed DNA breaks in lymphoid cells: repair mechanisms and consequences in human diseaseThe de-ubiquitylating enzymes USP26 and USP37 regulate homologous recombination by counteracting RAP80.Cell cycle-dependent control of homologous recombination.Priming and potentiation of DNA damage response by fibronectin in human colon cancer cells and tumor-derived myofibroblasts.
P2860
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P2860
RNF168, a new RING finger, MIU-containing protein that modifies chromatin by ubiquitination of histones H2A and H2AX
description
2009 nî lūn-bûn
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2009 թուականին հրատարակուած գիտական յօդուած
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2009 թվականին հրատարակված գիտական հոդված
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2009年の論文
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2009年論文
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2009年論文
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2009年論文
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2009年論文
@zh-mo
2009年論文
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2009年论文
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name
RNF168, a new RING finger, MIU ...... ation of histones H2A and H2AX
@ast
RNF168, a new RING finger, MIU ...... ation of histones H2A and H2AX
@en
RNF168, a new RING finger, MIU ...... ation of histones H2A and H2AX
@en-gb
RNF168, a new RING finger, MIU ...... ation of histones H2A and H2AX
@nl
type
label
RNF168, a new RING finger, MIU ...... ation of histones H2A and H2AX
@ast
RNF168, a new RING finger, MIU ...... ation of histones H2A and H2AX
@en
RNF168, a new RING finger, MIU ...... ation of histones H2A and H2AX
@en-gb
RNF168, a new RING finger, MIU ...... ation of histones H2A and H2AX
@nl
prefLabel
RNF168, a new RING finger, MIU ...... ation of histones H2A and H2AX
@ast
RNF168, a new RING finger, MIU ...... ation of histones H2A and H2AX
@en
RNF168, a new RING finger, MIU ...... ation of histones H2A and H2AX
@en-gb
RNF168, a new RING finger, MIU ...... ation of histones H2A and H2AX
@nl
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P2860
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P1476
RNF168, a new RING finger, MIU ...... ation of histones H2A and H2AX
@en
P2093
Cristina Scandiuzzi
Elisabetta Citterio
Lorenza Penengo
Nadia Arnaudo
Sabrina Pinato
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P2888
P3181
P356
10.1186/1471-2199-10-55
P407
P577
2009-01-01T00:00:00Z
P5875
P6179
1027614199