Structure and function of LGP2, a DEX(D/H) helicase that regulates the innate immunity response
about
Immune signaling by RIG-I-like receptorsRegulation of signal transduction by enzymatically inactive antiviral RNA helicase proteins MDA5, RIG-I, and LGP2The RIG-I-like receptor LGP2 recognizes the termini of double-stranded RNAParamyxovirus V proteins interact with the RNA Helicase LGP2 to inhibit RIG-I-dependent interferon inductionAgonist and Antagonist Recognition by RIG-I, a Cytoplasmic Innate Immunity ReceptorThe regulatory domain of the RIG-I family ATPase LGP2 senses double-stranded RNAStructural basis for dsRNA recognition and interferon antagonism by Ebola VP35The Structural Basis of 5′ Triphosphate Double-Stranded RNA Recognition by RIG-I C-Terminal DomainMDA5 cooperatively forms dimers and ATP-sensitive filaments upon binding double-stranded RNAStructural basis for the prion-like MAVS filaments in antiviral innate immunityInduction of type I interferon by RNA viruses: cellular receptors and their substratesLGP2: positive about viral sensing.Regulation of de novo-initiated RNA synthesis in hepatitis C virus RNA-dependent RNA polymerase by intermolecular interactions.Interplay between innate immunity and negative-strand RNA viruses: towards a rational modelSensing of viral nucleic acids by RIG-I: from translocation to translationDifferential recognition of double-stranded RNA by RIG-I-like receptors in antiviral immunity.Ancient origins of vertebrate-specific innate antiviral immunity.The laboratory of genetics and physiology 2: emerging insights into the controversial functions of this RIG-I-like receptor.Expanding role of ubiquitination in NF-κB signaling.Recognition of viruses in the cytoplasm by RLRs and other helicases--how conformational changes, mitochondrial dynamics and ubiquitination control innate immune responses.Toward a crystal-clear view of the viral RNA sensing and response by RIG-I-like receptors.Pattern Recognition and Signaling Mechanisms of RIG-I and MDA5Immune sensing of nucleic acids in inflammatory skin diseases.Molecular cloning, characterization and expression analysis of woodchuck retinoic acid-inducible gene I.Quantitative microspectroscopic imaging reveals viral and cellular RNA helicase interactions in live cells.Establishing the role of ATP for the function of the RIG-I innate immune sensorNegative regulators of the RIG-I-like receptor signaling pathway.An oligomeric signaling platform formed by the Toll-like receptor signal transducers MyD88 and IRAK-4.Laboratory of genetics and physiology 2 (LGP2) plays an essential role in hepatitis C virus infection-induced interferon responses.Cloning, characterization, and expression analysis of LGP2 cDNA from goose, Anser cygnoides.The thermodynamic basis for viral RNA detection by the RIG-I innate immune sensor.Viruses Seen by Our Cells: The Role of Viral RNA Sensors.
P2860
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P2860
Structure and function of LGP2, a DEX(D/H) helicase that regulates the innate immunity response
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2008年の論文
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2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
name
Structure and function of LGP2 ...... s the innate immunity response
@ast
Structure and function of LGP2 ...... s the innate immunity response
@en
Structure and function of LGP2 ...... s the innate immunity response
@en-gb
Structure and function of LGP2 ...... s the innate immunity response
@nl
type
label
Structure and function of LGP2 ...... s the innate immunity response
@ast
Structure and function of LGP2 ...... s the innate immunity response
@en
Structure and function of LGP2 ...... s the innate immunity response
@en-gb
Structure and function of LGP2 ...... s the innate immunity response
@nl
prefLabel
Structure and function of LGP2 ...... s the innate immunity response
@ast
Structure and function of LGP2 ...... s the innate immunity response
@en
Structure and function of LGP2 ...... s the innate immunity response
@en-gb
Structure and function of LGP2 ...... s the innate immunity response
@nl
P2093
P2860
P921
P356
P1476
Structure and function of LGP2 ...... s the innate immunity response
@en
P2093
Andreas Holzenburg
C Cheng Kao
C T Ranjith-Kumar
Kanchan Bhardwaj
Pingwei Li
Xiaojun Li
P2860
P304
P356
10.1074/JBC.M800542200
P407
P577
2008-06-06T00:00:00Z