Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway
about
PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodiaStructure of Cdc42 in complex with the GTPase-binding domain of the 'Wiskott-Aldrich syndrome' proteinMSE55, a Cdc42 effector protein, induces long cellular extensions in fibroblastsHuman JIK, a novel member of the STE20 kinase family that inhibits JNK and is negatively regulated by epidermal growth factorPSK, a novel STE20-like kinase derived from prostatic carcinoma that activates the c-Jun N-terminal kinase mitogen-activated protein kinase pathway and regulates actin cytoskeletal organizationCdc42-induced activation of the mixed-lineage kinase SPRK in vivo. Requirement of the Cdc42/Rac interactive binding motif and changes in phosphorylationSPECs, small binding proteins for Cdc42SPAK, a STE20/SPS1-related kinase that activates the p38 pathwayInvolvement of alpha-PAK-interacting exchange factor in the PAK1-c-Jun NH(2)-terminal kinase 1 activation and apoptosis induced by benzo[a]pyreneThe C-terminal kinase domain of the p34cdc2-related PITSLRE protein kinase (p110C) associates with p21-activated kinase 1 and inhibits its activity during anoikisCharacterization of OSR1, a member of the mammalian Ste20p/germinal center kinase subfamilyHPK1, a hematopoietic protein kinase activating the SAPK/JNK pathwayMyotonic dystrophy kinase-related Cdc42-binding kinase acts as a Cdc42 effector in promoting cytoskeletal reorganizationCloning and characterization of a human STE20-like protein kinase with unusual cofactor requirementsThe MAP kinase kinase kinase MLK2 co-localizes with activated JNK along microtubules and associates with kinesin superfamily motor KIF3A new rac target POSH is an SH3-containing scaffold protein involved in the JNK and NF-kappaB signalling pathwaysTyrosine 221 in Crk regulates adhesion-dependent membrane localization of Crk and Rac and activation of Rac signaling.PAK5, a new brain-specific kinase, promotes neurite outgrowth in N1E-115 cellsTumor metastasis suppressor nm23H1 regulates Rac1 GTPase by interaction with Tiam1Expression of constitutively active alpha-PAK reveals effects of the kinase on actin and focal complexesp21-Activated kinase 5 (Pak5) localizes to mitochondria and inhibits apoptosis by phosphorylating BADSodium arsenite-induced stress-related gene expression in normal human epidermal, HaCaT, and HEL30 keratinocytes.Pak1 regulates the orientation of apical polarization and lumen formation by distinct pathwaysHsl7p, a negative regulator of Ste20p protein kinase in the Saccharomyces cerevisiae filamentous growth-signaling pathway.Novel Cdc42-binding proteins Gic1 and Gic2 control cell polarity in yeast.Functional analysis of the interaction between the small GTP binding protein Cdc42 and the Ste20 protein kinase in yeast.The yeast centrin, cdc31p, and the interacting protein kinase, Kic1p, are required for cell integrityThe p21-activated protein kinase inhibitor Skb15 and its budding yeast homologue are 60S ribosome assembly factors.Cdc42 regulation of kinase activity and signaling by the yeast p21-activated kinase Ste20.Cdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity.Multisite autophosphorylation of p21-activated protein kinase gamma-PAK as a function of activationA tyrosine-phosphorylated protein that binds to an important regulatory region on the cool family of p21-activated kinase-binding proteinsalphaPIX nucleotide exchange factor is activated by interaction with phosphatidylinositol 3-kinaseInvolvement of Hgs/Hrs in signaling for cytokine-mediated c-fos induction through interaction with TAK1 and Pak1The Cbl proteins are binding partners for the Cool/Pix family of p21-activated kinase-binding proteinsPAK4 kinase is essential for embryonic viability and for proper neuronal developmentThe serine/threonine kinase PAK4 prevents caspase activation and protects cells from apoptosisAkt phosphorylation of serine 21 on Pak1 modulates Nck binding and cell migrationActivated PAK4 regulates cell adhesion and anchorage-independent growthNuclear localization and chromatin targets of p21-activated kinase 1
P2860
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P2860
Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway
description
1996 nî lūn-bûn
@nan
1996 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway
@ast
Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway
@en
Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway
@en-gb
Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway
@nl
type
label
Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway
@ast
Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway
@en
Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway
@en-gb
Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway
@nl
prefLabel
Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway
@ast
Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway
@en
Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway
@en-gb
Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway
@nl
P2093
P921
P1433
P1476
Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway
@en
P2093
P304
P356
10.1016/S0960-9822(02)00546-8
P407
P577
1996-05-01T00:00:00Z