HPK1, a hematopoietic protein kinase activating the SAPK/JNK pathway
about
Direct activation of mitogen-activated protein kinase kinase kinase MEKK1 by the Ste20p homologue GCK and the adapter protein TRAF2.A new identity for MLK3 as an NIMA-related, cell cycle-regulated kinase that is localized near centrosomes and influences microtubule organization.Hepatitis C virus NS5A inhibits mixed lineage kinase 3 to block apoptosisThe CUL7/F-box and WD repeat domain containing 8 (CUL7/Fbxw8) ubiquitin ligase promotes degradation of hematopoietic progenitor kinase 1Activation of the c-Jun N-terminal kinase pathway by a novel protein kinase related to human germinal center kinaseInteraction of hematopoietic progenitor kinase 1 with adapter proteins Crk and CrkL leads to synergistic activation of c-Jun N-terminal kinase.Mixed-lineage kinase 2-SH3 domain binds dynamin and greatly enhances activation of GTPase by phospholipidTumorigenesis suppressor Pdcd4 down-regulates mitogen-activated protein kinase kinase kinase kinase 1 expression to suppress colon carcinoma cell invasionMolecular cloning and characterization of human JNKK2, a novel Jun NH2-terminal kinase-specific kinaseIdentification of genes expressed in human CD34(+) hematopoietic stem/progenitor cells by expressed sequence tags and efficient full-length cDNA cloningB cell adaptor containing src homology 2 domain (BASH) links B cell receptor signaling to the activation of hematopoietic progenitor kinase 1The MKK7 gene encodes a group of c-Jun NH2-terminal kinase kinasesRegulation of mixed-lineage kinase activation in JNK-dependent morphogenesis.The Caenorhabditis elegans Ste20-related kinase and Rac-type small GTPase regulate the c-Jun N-terminal kinase signaling pathway mediating the stress responseHPK1 associates with SKAP-HOM to negatively regulate Rap1-mediated B-lymphocyte adhesion.Pro-oncogenic function of HIP-55/Drebrin-like (DBNL) through Ser269/Thr291-phospho-sensor motifs.Activation of MEK kinase 1 by the c-Abl protein tyrosine kinase in response to DNA damage.Synergistic regulation of immunoreceptor signaling by SLP-76-related adaptor Clnk and serine/threonine protein kinase HPK-1.Epstein-barr virus-induced changes in B-lymphocyte gene expression.Structural requirements of SLP-76 in signaling via the high-affinity immunoglobulin E receptor (Fc epsilon RI) in mast cellsGenetic analysis of slipper/mixed lineage kinase reveals requirements in multiple Jun-N-terminal kinase-dependent morphogenetic events during Drosophila development.Dual role of hematopoietic progenitor kinase 1 (HPK1) as a positive regulator of 1α,25-dihydroxyvitamin D-induced differentiation and cell cycle arrest of AML cells and as a mediator of vitamin D resistancePrognostic and Functional Significance of MAP4K5 in Pancreatic Cancer.A novel pathway down-modulating T cell activation involves HPK-1-dependent recruitment of 14-3-3 proteins on SLP-76.Attenuation of T cell receptor signaling by serine phosphorylation-mediated lysine 30 ubiquitination of SLP-76 protein.Mixed lineage kinases (MLKs): a role in dendritic cells, inflammation and immunity?Pdcd4 knockdown up-regulates MAP4K1 expression and activation of AP-1 dependent transcription through c-Myc.Phosphorylation of CARMA1 by HPK1 is critical for NF-kappaB activation in T cells.Mixed Lineage Kinase-c-Jun N-Terminal Kinase Axis: A Potential Therapeutic Target in Cancer.The LAT story: a tale of cooperativity, coordination, and choreography.Adenovirus E1B 19,000-molecular-weight protein activates c-Jun N-terminal kinase and c-Jun-mediated transcription.Proteasome-mediated degradation and functions of hematopoietic progenitor kinase 1 in pancreatic cancerActivation or suppression of NFkappaB by HPK1 determines sensitivity to activation-induced cell death.Activation of hematopoietic progenitor kinase 1 involves relocation, autophosphorylation, and transphosphorylation by protein kinase D1.MLK-3 activates the SAPK/JNK and p38/RK pathways via SEK1 and MKK3/6Identification of two distinct peptide-binding pockets in the SH3 domain of human mixed-lineage kinase 3
P2860
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P2860
HPK1, a hematopoietic protein kinase activating the SAPK/JNK pathway
description
1996 nî lūn-bûn
@nan
1996 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
HPK1, a hematopoietic protein kinase activating the SAPK/JNK pathway
@ast
HPK1, a hematopoietic protein kinase activating the SAPK/JNK pathway
@en
HPK1, a hematopoietic protein kinase activating the SAPK/JNK pathway
@en-gb
HPK1, a hematopoietic protein kinase activating the SAPK/JNK pathway
@nl
type
label
HPK1, a hematopoietic protein kinase activating the SAPK/JNK pathway
@ast
HPK1, a hematopoietic protein kinase activating the SAPK/JNK pathway
@en
HPK1, a hematopoietic protein kinase activating the SAPK/JNK pathway
@en-gb
HPK1, a hematopoietic protein kinase activating the SAPK/JNK pathway
@nl
prefLabel
HPK1, a hematopoietic protein kinase activating the SAPK/JNK pathway
@ast
HPK1, a hematopoietic protein kinase activating the SAPK/JNK pathway
@en
HPK1, a hematopoietic protein kinase activating the SAPK/JNK pathway
@en-gb
HPK1, a hematopoietic protein kinase activating the SAPK/JNK pathway
@nl
P2093
P2860
P3181
P1433
P1476
HPK1, a hematopoietic protein kinase activating the SAPK/JNK pathway
@en
P2093
Tibbles LA
Woodgett JR
P2860
P304
P3181
P356
10.1002/J.1460-2075.1996.TB01093.X
P407
P577
1996-12-01T00:00:00Z