The promyelocytic leukemia gene product (PML) forms stable complexes with the retinoblastoma protein
about
Potentiation of GATA-2 activity through interactions with the promyelocytic leukemia protein (PML) and the t(15;17)-generated PML-retinoic acid receptor alpha oncoproteinRegulation of p53 activity in nuclear bodies by a specific PML isoformThe growth suppressor PML represses transcription by functionally and physically interacting with histone deacetylasesA diverse family of proteins containing tumor necrosis factor receptor-associated factor domainsA new spectrin, beta IV, has a major truncated isoform that associates with promyelocytic leukemia protein nuclear bodies and the nuclear matrixHuman SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence.PML colocalizes with and stabilizes the DNA damage response protein TopBP1MOZ increases p53 acetylation and premature senescence through its complex formation with PMLSUMO conjugation to the matrix attachment region-binding protein, special AT-rich sequence-binding protein-1 (SATB1), targets SATB1 to promyelocytic nuclear bodies where it undergoes caspase cleavageThe promyelocytic leukemia protein interacts with Sp1 and inhibits its transactivation of the epidermal growth factor receptor promoterProteasome-independent disruption of PML oncogenic domains (PODs), but not covalent modification by SUMO-1, is required for human cytomegalovirus immediate-early protein IE1 to inhibit PML-mediated transcriptional repression.Epstein-barr virus immediate-early protein BZLF1 is SUMO-1 modified and disrupts promyelocytic leukemia bodiesRecruitment of the NCoA/SRC-1/p160 family of transcriptional coactivators by the aryl hydrocarbon receptor/aryl hydrocarbon receptor nuclear translocator complexInactivating a cellular intrinsic immune defense mediated by Daxx is the mechanism through which the human cytomegalovirus pp71 protein stimulates viral immediate-early gene expressionRepression of PML nuclear body-associated transcription by oxidative stress-activated Bach2The transcriptional role of PML and the nuclear bodyRegulation of Pax3 transcriptional activity by SUMO-1-modified PMLPML protein isoforms and the RBCC/TRIM motifPML interaction with p53 and its role in apoptosis and replicative senescenceNuclear-cytoplasmic shuttling of a RING-IBR protein RBCK1 and its functional interaction with nuclear body proteinsPIC-1/SUMO-1-modified PML-retinoic acid receptor alpha mediates arsenic trioxide-induced apoptosis in acute promyelocytic leukemiaImmediate early gene X1 (IEX-1) is organized in subnuclear structures and partially co-localizes with promyelocytic leukemia protein in HeLa cells.Recruitment of the histone methyltransferase SUV39H1 and its role in the oncogenic properties of the leukemia-associated PML-retinoic acid receptor fusion protein.Pondering the promyelocytic leukemia protein (PML) puzzle: possible functions for PML nuclear bodies.The pathogenesis of acute promyelocytic leukaemia: evaluation of the role of molecular diagnosis and monitoring in the management of the disease.Interactions of herpes simplex virus type 1 with ND10 and recruitment of PML to replication compartments.Deconstructing PML-induced premature senescence.Cellular proteins localized at and interacting within ND10/PML nuclear bodies/PODs suggest functions of a nuclear depot.Effects of promyelocytic leukemia protein on virus-host balance.PML-mediated signaling and its role in cancer stem cells.Orchestration of multiple arrays of signal cross-talk and combinatorial interactions for maturation and cell death: another vision of t(15;17) preleukemic blast and APL-cell maturation.Transcriptional regulation in acute promyelocytic leukemia.PODs in the nuclear spot: enigmas in the magician's pot.Chromatin modification, leukaemia and implications for therapy.A Role for PML in Innate ImmunityPML is induced by oncogenic ras and promotes premature senescencePromyelocytic leukemia inhibits adipogenesis, and loss of promyelocytic leukemia results in fat accumulation in mice.Expression of a bcr-1 isoform of RARalpha-PML does not affect the penetrance of acute promyelocytic leukemia or the acquisition of an interstitial deletion on mouse chromosome 2Deficiencies in Cellular Processes Modulated by the Retinoblastoma Protein Do Not Account for Reduced Human Cytomegalovirus Replication in Its AbsenceHuman cytomegalovirus UL97 kinase activity is required for the hyperphosphorylation of retinoblastoma protein and inhibits the formation of nuclear aggresomes.
P2860
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P2860
The promyelocytic leukemia gene product (PML) forms stable complexes with the retinoblastoma protein
description
1998 nî lūn-bûn
@nan
1998 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
The promyelocytic leukemia gen ...... ith the retinoblastoma protein
@ast
The promyelocytic leukemia gen ...... ith the retinoblastoma protein
@en
The promyelocytic leukemia gen ...... ith the retinoblastoma protein
@en-gb
The promyelocytic leukemia gen ...... ith the retinoblastoma protein
@nl
type
label
The promyelocytic leukemia gen ...... ith the retinoblastoma protein
@ast
The promyelocytic leukemia gen ...... ith the retinoblastoma protein
@en
The promyelocytic leukemia gen ...... ith the retinoblastoma protein
@en-gb
The promyelocytic leukemia gen ...... ith the retinoblastoma protein
@nl
prefLabel
The promyelocytic leukemia gen ...... ith the retinoblastoma protein
@ast
The promyelocytic leukemia gen ...... ith the retinoblastoma protein
@en
The promyelocytic leukemia gen ...... ith the retinoblastoma protein
@en-gb
The promyelocytic leukemia gen ...... ith the retinoblastoma protein
@nl
P2093
P2860
P921
P356
P1476
The promyelocytic leukemia gen ...... ith the retinoblastoma protein
@en
P2093
F Grignani
L Tomassoni
P G Pelicci
P2860
P304
P356
10.1128/MCB.18.2.1084
P407
P577
1998-02-01T00:00:00Z