Recruitment of the histone methyltransferase SUV39H1 and its role in the oncogenic properties of the leukemia-associated PML-retinoic acid receptor fusion protein.
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The function, regulation and therapeutic implications of the tumor suppressor protein, PMLCrystal Structure of the Human SUV39H1 Chromodomain and Its Recognition of Histone H3K9me2/3Mechanisms of action and resistance to all-trans retinoic acid (ATRA) and arsenic trioxide (As2O 3) in acute promyelocytic leukemia.ASXL1 represses retinoic acid receptor-mediated transcription through associating with HP1 and LSD1Differentiation therapy of leukemia: 3 decades of development.Myxoid liposarcoma-associated EWSR1-DDIT3 selectively represses osteoblastic and chondrocytic transcription in multipotent mesenchymal cells.RFX1 regulates CD70 and CD11a expression in lupus T cells by recruiting the histone methyltransferase SUV39H1Chromatin modifications induced by PML-RARalpha repress critical targets in leukemogenesis as analyzed by ChIP-Chip.Epigenetic regulation of normal and malignant hematopoiesis.Division of labor between the chromodomains of HP1 and Suv39 methylase enables coordination of heterochromatin spread.The histone H3K9 methyltransferase SUV39H links SIRT1 repression to myocardial infarction.Genome-wide functions of PML-RARα in acute promyelocytic leukaemiaKey roles of histone methyltransferase and demethylase in leukemogenesis.How to control an infectious bead string: nucleosome-based regulation and targeting of herpesvirus chromatin.Interplay between Herpesvirus Infection and Host Defense by PML Nuclear BodiesDifferentiation therapy of acute myeloid leukemia.Epigenetics in acute promyelocytic leukaemia pathogenesis and treatment response: a TRAnsition to targeted therapies.Role of histone lysine methyltransferases SUV39H1 and SETDB1 in gliomagenesis: modulation of cell proliferation, migration, and colony formation.The Human CMV IE1 Protein: An Offender of PML Nuclear Bodies.Reexpression of epigenetically silenced AML tumor suppressor genes by SUV39H1 inhibition.Aberrant association of promyelocytic leukemia protein-retinoic acid receptor-alpha with coactivators contributes to its ability to regulate gene expression.Anti-leukemia activity of chaetocin via death receptor-dependent apoptosis and dual modulation of the histone methyl-transferase SUV39H1.Disclosing the crosstalk among DNA methylation, transcription factors, and histone marks in human pluripotent cells through discovery of DNA methylation motifs.The retinoblastoma protein and PML collaborate to organize heterochromatin and silence E2F-responsive genes during senescence.Redistribution of cell cycle by arsenic trioxide is associated with demethylation and expression changes of cell cycle related genes in acute promyelocytic leukemia cell line (NB4).Chromatin modifications induced by the AML1-ETO fusion protein reversibly silence its genomic targets through AML1 and Sp1 binding motifs.The self-association coiled-coil domain of PML is sufficient for the oncogenic conversion of the retinoic acid receptor (RAR) alpha.Multi-omics profiling reveals a distinctive epigenome signature for high-risk acute promyelocytic leukemia.Histone méthyltransférases
P2860
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P2860
Recruitment of the histone methyltransferase SUV39H1 and its role in the oncogenic properties of the leukemia-associated PML-retinoic acid receptor fusion protein.
description
2006 nî lūn-bûn
@nan
2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Recruitment of the histone met ...... acid receptor fusion protein.
@ast
Recruitment of the histone met ...... acid receptor fusion protein.
@en
Recruitment of the histone met ...... acid receptor fusion protein.
@nl
type
label
Recruitment of the histone met ...... acid receptor fusion protein.
@ast
Recruitment of the histone met ...... acid receptor fusion protein.
@en
Recruitment of the histone met ...... acid receptor fusion protein.
@nl
prefLabel
Recruitment of the histone met ...... acid receptor fusion protein.
@ast
Recruitment of the histone met ...... acid receptor fusion protein.
@en
Recruitment of the histone met ...... acid receptor fusion protein.
@nl
P2093
P2860
P1476
Recruitment of the histone met ...... acid receptor fusion protein.
@en
P2093
Alessandra Insinga
Oronza A Botrugno
Pier Giuseppe Pelicci
Roberta Carbone
Saverio Minucci
Simona Ronzoni
P2860
P304
P356
10.1128/MCB.26.4.1288-1296.2006
P407
P577
2006-02-01T00:00:00Z