Human respiratory syncytial virus nonstructural protein NS2 antagonizes the activation of beta interferon transcription by interacting with RIG-I - Test2 - elhamkhani - TriplyDB

Human respiratory syncytial virus nonstructural protein NS2 antagonizes the activation of beta interferon transcription by interacting with RIG-I

Human respiratory syncytial virus nonstructural protein NS2 antagonizes the activation of beta interferon transcription by interacting with RIG-I

http://www.wikidata.org/entity/Q24336258

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Z proteins of New World arenaviruses bind RIG-I and interfere with type I interferon induction Human metapneumovirus M2-2 protein inhibits innate cellular signaling by targeting MAVS Herpes simplex virus 1 tegument protein US11 downmodulates the RLR signaling pathway via direct interaction with RIG-I and MDA-5 Human respiratory syncytial virus nucleoprotein and inclusion bodies antagonize the innate immune response mediated by MDA5 and MAVS Toscana virus NSs protein inhibits the induction of type I interferon by interacting with RIG-I Modulation of host adaptive immunity by hRSV proteins Both RIG-I and MDA5 RNA Helicases Contribute to the Induction of Alpha/Beta Interferon in Measles Virus-Infected Human Cells Host cytoskeleton in respiratory syncytial virus assembly and budding Respiratory syncytial virus NS1 protein colocalizes with mitochondrial antiviral signaling protein MAVS following infection The non-structural NS1 protein unique to respiratory syncytial virus: a two-state folding monomer in quasi-equilibrium with a stable spherical oligomer RSV-Induced H3K4 Demethylase KDM5B Leads to Regulation of Dendritic Cell-Derived Innate Cytokines and Exacerbates Pathogenesis In Vivo The interactome of the human respiratory syncytial virus NS1 protein highlights multiple effects on host cell biology Activation of IFN-β expression by a viral mRNA through RNase L and MDA5 The nucleolar protein GLTSCR2 is required for efficient viral replication RSV-encoded NS2 promotes epithelial cell shedding and distal airway obstruction.Respiratory viral infections in infants: causes, clinical symptoms, virology, and immunology.Respiratory infections by HMPV and RSV are clinically indistinguishable but induce different host response in aged individuals.Respiratory syncytial virus interferon antagonist NS1 protein suppresses and skews the human T lymphocyte response Recombinant human parainfluenza virus type 2 with mutations in V that permit cellular interferon signaling are not attenuated in non-human primates.Interplay between innate immunity and negative-strand RNA viruses: towards a rational model Refining the balance of attenuation and immunogenicity of respiratory syncytial virus by targeted codon deoptimization of virulence genes Viral and host factors determine innate immune responses in airway epithelial cells from children with wheeze and atopy.Respiratory syncytial virus infections in the adult asthmatic--mechanisms of host susceptibility and viral subversion.Immunity to RSV in Early-Life.Decreased Toll-like receptor 8 expression and lower TNF-α synthesis in infants with acute RSV infection Leukemia inhibitory factor protects the lung during respiratory syncytial viral infection.Current concepts and progress in RSV vaccine development.The airway epithelium: soldier in the fight against respiratory viruses Biological challenges and technological opportunities for respiratory syncytial virus vaccine development.Molecular Mechanisms of Innate Immune Inhibition by Non-Segmented Negative-Sense RNA Viruses.A live RSV vaccine with engineered thermostability is immunogenic in cotton rats despite high attenuation A comprehensive proteomic view of responses of A549 type II alveolar epithelial cells to human respiratory syncytial virus infection Respiratory syncytial virus induced type I IFN production by pDC is regulated by RSV-infected airway epithelial cells, RSV-exposed monocytes and virus specific antibodies Both nonstructural proteins NS1 and NS2 of pneumonia virus of mice are inhibitors of the interferon type I and type III responses in vivo.An overview of respiratory syncytial virus.Progress in understanding and controlling respiratory syncytial virus: still crazy after all these years Alveolar macrophage-derived type I interferons orchestrate innate immunity to RSV through recruitment of antiviral monocytes Immunostimulatory Defective Viral Genomes from Respiratory Syncytial Virus Promote a Strong Innate Antiviral Response during Infection in Mice and Humans.A novel mechanism for the inhibition of interferon regulatory factor-3-dependent gene expression by human respiratory syncytial virus NS1 protein.Respiratory Syncytial Virus-Infected Mesenchymal Stem Cells Regulate Immunity via Interferon Beta and Indoleamine-2,3-Dioxygenase

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Human respiratory syncytial virus nonstructural protein NS2 antagonizes the activation of beta interferon transcription by interacting with RIG-I

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2009 nî lūn-bûn

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2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2009 թվականի ապրիլին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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Human respiratory syncytial vi ...... tion by interacting with RIG-I

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Kim C Tran

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Michael N Teng

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Zhenhua Ling

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P2860

Human metapneumovirus glycoprotein G inhibits innate immune responses

Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3...

Inhibition of retinoic acid-inducible gene I-mediated induction of beta interferon by the NS1 protein of influenza A virus

IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation

Rotavirus nonstructural protein 1 subverts innate immune response by inducing degradation of IFN regulatory factor 3

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates

Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3

TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity

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3734-42

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10.1128/JVI.02434-08

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19193793

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