The Ccr4a (CNOT6) and Ccr4b (CNOT6L) deadenylase subunits of the human Ccr4-Not complex contribute to the prevention of cell death and senescence
about
The anti-proliferative activity of BTG/TOB proteins is mediated via the Caf1a (CNOT7) and Caf1b (CNOT8) deadenylase subunits of the Ccr4-not complexRNA processing and modification protein, carbon catabolite repression 4 (Ccr4), arrests the cell cycle through p21-dependent and p53-independent pathwayProteins involved in the degradation of cytoplasmic mRNA in the major eukaryotic model systemsHeterogeneity and complexity within the nuclease module of the Ccr4-Not complexPost-transcriptional Control of Tumor Cell Autonomous Metastatic Potential by CCR4-NOT Deadenylase CNOT7The CCR4-NOT complex mediates deadenylation and degradation of stem cell mRNAs and promotes planarian stem cell differentiationIdentification and characterization of FGF2-dependent mRNA: microRNA networks during lens fiber cell differentiationObesity resistance and increased hepatic expression of catabolism-related mRNAs in Cnot3+/- miceSusceptibility loci of CNOT6 in the general mRNA degradation pathway and lung cancer risk - a re-analysis of eight GWASsInsights into the structure and architecture of the CCR4-NOT complexGenome-wide analysis of alternative splicing during dendritic cell response to a bacterial challenge.Genome-wide association study for feed efficiency and growth traits in U.S. beef cattleMultifunctional roles of the mammalian CCR4-NOT complex in physiological phenomena.The PARN deadenylase targets a discrete set of mRNAs for decay and regulates cell motility in mouse myoblastsChanges in poly(A) tail length dynamics from the loss of the circadian deadenylase NocturninImportant miRs of pathways in different tumor types.Interaction of NANOS2 and NANOS3 with different components of the CNOT complex may contribute to the functional differences in mouse male germ cells.A fluorescence-based assay suitable for quantitative analysis of deadenylase enzyme activity.Xrn1/Pacman affects apoptosis and regulates expression of hid and reaper.Co-Transcriptomes of Initial Interactions In Vitro between Streptococcus Pneumoniae and Human Pleural Mesothelial Cells.Interaction between NANOS2 and the CCR4-NOT deadenylation complex is essential for male germ cell development in mouse.Discovery, synthesis and biochemical profiling of purine-2,6-dione derivatives as inhibitors of the human poly(A)-selective ribonuclease Caf1.A non-proteolytic role for ubiquitin in deadenylation of MHC-I mRNA by the RNA-binding E3-ligase MEX-3C.Fibroblast growth factor (FGF) signaling during gastrulation negatively modulates the abundance of microRNAs that regulate proteins required for cell migration and embryo patterningKiss your tail goodbye: the role of PARN, Nocturnin, and Angel deadenylases in mRNA biology.The 5'-3' exoribonuclease Pacman (Xrn1) regulates expression of the heat shock protein Hsp67Bc and the microRNA miR-277-3p in Drosophila wing imaginal discs.Deadenylation of cytoplasmic mRNA by the mammalian Ccr4-Not complex.MicroRNA transport: a new way in cell communication.Deadenylation: enzymes, regulation, and functional implications.Expanding the repertoire of deadenylases.Divergence of the expression and subcellular localization of CCR4-associated factor 1 (CAF1) deadenylase proteins in Oryza sativa.AtHESPERIN: a novel regulator of circadian rhythms with poly(A)-degrading activity in plants.Alterations in mRNA 3' UTR Isoform Abundance Accompany Gene Expression Changes in Human Huntington's Disease Brains.The enzyme activities of Caf1 and Ccr4 are both required for deadenylation by the human Ccr4-Not nuclease module.The Ccr4-Not Complex: Architecture and Structural Insights.Novel interaction between CCR4 and CAF1 in rice CCR4-NOT deadenylase complex.Beyond the known functions of the CCR4-NOT complex in gene expression regulatory mechanisms: New structural insights to unravel CCR4-NOT mRNA processing machinery.The conserved RNA recognition motif and C3H1 domain of the Not4 ubiquitin ligase regulate in vivo ligase function.Integrated bioinformatic changes and analysis of retina with time in diabetic rats.
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P2860
The Ccr4a (CNOT6) and Ccr4b (CNOT6L) deadenylase subunits of the human Ccr4-Not complex contribute to the prevention of cell death and senescence
description
2011 nî lūn-bûn
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2011 թուականի Մարտին հրատարակուած գիտական յօդուած
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2011 թվականի մարտին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
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2011年論文
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2011年論文
@zh-hk
2011年論文
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2011年論文
@zh-tw
2011年论文
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name
The Ccr4a (CNOT6) and Ccr4b (C ...... n of cell death and senescence
@ast
The Ccr4a (CNOT6) and Ccr4b (C ...... n of cell death and senescence
@en
The Ccr4a (CNOT6) and Ccr4b (C ...... n of cell death and senescence
@en-gb
The Ccr4a (CNOT6) and Ccr4b (C ...... n of cell death and senescence
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type
label
The Ccr4a (CNOT6) and Ccr4b (C ...... n of cell death and senescence
@ast
The Ccr4a (CNOT6) and Ccr4b (C ...... n of cell death and senescence
@en
The Ccr4a (CNOT6) and Ccr4b (C ...... n of cell death and senescence
@en-gb
The Ccr4a (CNOT6) and Ccr4b (C ...... n of cell death and senescence
@nl
prefLabel
The Ccr4a (CNOT6) and Ccr4b (C ...... n of cell death and senescence
@ast
The Ccr4a (CNOT6) and Ccr4b (C ...... n of cell death and senescence
@en
The Ccr4a (CNOT6) and Ccr4b (C ...... n of cell death and senescence
@en-gb
The Ccr4a (CNOT6) and Ccr4b (C ...... n of cell death and senescence
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P2093
P2860
P921
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The Ccr4a (CNOT6) and Ccr4b (C ...... n of cell death and senescence
@en
P2093
Akhmed Aslam
Rachel Doidge
Rachel Medica
Saloni Mittal
P2860
P304
P356
10.1091/MBC.E10-11-0898
P407
P50
P577
2011-01-13T00:00:00Z