Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation
about
MicroRNA-122 modulates the rhythmic expression profile of the circadian deadenylase Nocturnin in mouse liver.miRNA repression involves GW182-mediated recruitment of CCR4-NOT through conserved W-containing motifsmiRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4-NOTCCR4-NOT deadenylates mRNA associated with RNA-induced silencing complexes in human cellsDistinct functions of maternal and somatic Pat1 protein paralogsStructural basis of binding of P-body-associated proteins GW182 and ataxin-2 by the Mlle domain of poly(A)-binding proteinThe interactions of GW182 proteins with PABP and deadenylases are required for both translational repression and degradation of miRNA targetsTwo PABPC1-binding sites in GW182 proteins promote miRNA-mediated gene silencingPhosphorylation at intrinsically disordered regions of PAM2 motif-containing proteins modulates their interactions with PABPC1 and influences mRNA fateGW182 proteins cause PABP dissociation from silenced miRNA targets in the absence of deadenylationStructural features of Argonaute-GW182 protein interactionsThe Ccr4a (CNOT6) and Ccr4b (CNOT6L) deadenylase subunits of the human Ccr4-Not complex contribute to the prevention of cell death and senescencemiRNA-mediated gene silencing by translational repression followed by mRNA deadenylation and decayePAT: a simple method to tag adenylated RNA to measure poly(A)-tail length and other 3' RACE applicationsHuman SP-A1 (SFTPA1) variant-specific 3' UTRs and poly(A) tail differentially affect the in vitro translation of a reporter geneRibosome profiling shows that miR-430 reduces translation before causing mRNA decay in zebrafishSequence context outside the target region influences the effectiveness of miR-223 target sites in the RhoB 3'UTRThe organization and regulation of mRNA-protein complexesThe Role of microRNAs in the Pathogenesis of Herpesvirus InfectionTiny giants of gene regulation: experimental strategies for microRNA functional studiesBiogenesis, turnover, and mode of action of plant microRNAsMechanisms of deadenylation-dependent decayPrinciples of translational control: an overviewThe panorama of miRNA-mediated mechanisms in mammalian cellsBiogenesis and mechanism of action of small non-coding RNAs: insights from the point of view of structural biologyThe role of mammalian poly(A)-binding proteins in co-ordinating mRNA turnoverThe CCR4-NOT complex mediates deadenylation and degradation of stem cell mRNAs and promotes planarian stem cell differentiationClk post-transcriptional control denoises circadian transcription both temporally and spatially.Structural insights into the human GW182-PABC interaction in microRNA-mediated deadenylationeIF4GI facilitates the MicroRNA-mediated gene silencingRNA-based mechanisms regulating host-virus interactionsThe TAL effector PthA4 interacts with nuclear factors involved in RNA-dependent processes including a HMG protein that selectively binds poly(U) RNAAnti-PABPC1 co-immunoprecipitation for examining the miRNAs directly targeting the 3'-UTR of EED mRNAObesity resistance and increased hepatic expression of catabolism-related mRNAs in Cnot3+/- micePlakophilins 1 and 3 bind to FXR1 and thereby influence the mRNA stability of desmosomal proteinsThe mechanism of eukaryotic translation initiation and principles of its regulationhCAF1/CNOT7 regulates interferon signalling by targeting STAT1.miR-199a-5p regulates HIF-1α and OSGIN2 and its expression is correlated to soft-tissue sarcoma patients' outcomeRNA Genes: Retroelements and Virally Retroposable microRNAs in Human Embryonic Stem Cells.RNA-binding protein GLD-1/quaking genetically interacts with the mir-35 and the let-7 miRNA pathways in Caenorhabditis elegans.
P2860
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P248
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P2860
Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation
description
2009 nî lūn-bûn
@nan
2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation
@ast
Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation
@en
Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation
@en-gb
Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation
@nl
type
label
Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation
@ast
Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation
@en
Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation
@en-gb
Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation
@nl
prefLabel
Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation
@ast
Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation
@en
Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation
@en-gb
Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation
@nl
P2093
P2860
P50
P921
P3181
P1433
P1476
Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation
@en
P2093
Ann-Bin Shyu
Chyi-Ying A Chen
Fabiola Rivas
Géraldine Mathonnet
Hansruedi Mathys
Jakob T Zipprich
James Wohlschlegel
John R Yates
Marc R Fabian
Thomas F Duchaine
P2860
P304
P3181
P356
10.1016/J.MOLCEL.2009.08.004
P407
P5008
P577
2009-09-24T00:00:00Z