Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma
about
The spectrum of SWI/SNF mutations, ubiquitous in human cancersExome sequencing and functional analysis identifies a novel mutation in EXT1 gene that causes multiple osteochondromasSS18 together with animal-specific factors defines human BAF-type SWI/SNF complexesHuman genetics and genomics a decade after the release of the draft sequence of the human genomeSinefungin derivatives as inhibitors and structure probes of protein lysine methyltransferase SETD2Reversible disruption of mSWI/SNF (BAF) complexes by the SS18-SSX oncogenic fusion in synovial sarcomaThe histone mark H3K36me3 regulates human DNA mismatch repair through its interaction with MutSαPancreatic cancer genomes reveal aberrations in axon guidance pathway genesNCG 4.0: the network of cancer genes in the era of massive mutational screenings of cancer genomesMetabolism of kidney cancer: from the lab to clinical practiceARID2: a new tumor suppressor gene in hepatocellular carcinomaA decade of exploring the cancer epigenome - biological and translational implicationsIntegrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastomaState of the science: an update on renal cell carcinomaConvergent structural alterations define SWItch/Sucrose NonFermentable (SWI/SNF) chromatin remodeler as a central tumor suppressive complex in pancreatic cancerTargeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cellsSequential pathogenesis of metastatic VHL mutant clear cell renal cell carcinoma: putting it together with a translational perspectiveEpigenetic modulators, modifiers and mediators in cancer aetiology and progressionMammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomicsGenomic alterations in pancreatic cancer and their relevance to therapyGenetic and Chromosomal Aberrations and Their Clinical Significance in Renal NeoplasmsFrom human genome to cancer genome: the first decadeMetastatic renal cell carcinoma: update on epidemiology, genetics, and therapeutic modalitiesDecade in review-kidney cancer: discoveries, therapies and opportunitiesRenal tumors: diagnostic and prognostic biomarkersEpigenetic dysregulation: a novel pathway of oncogenesis in pediatric brain tumorsKidney cancerHow many molecular subtypes? Implications of the unique tumor principle in personalized medicineSWI/SNF chromatin remodeling complexes and cancerMyeloid malignancies: mutations, models and managementSWI/SNF chromatin-remodeling factors: multiscale analyses and diverse functionsNew insights and challenges in mismatch repair: getting over the chromatin hurdleTargeted therapeutic strategies for the management of renal cell carcinomaEmerging patterns of somatic mutations in cancerHistone deacetylase inhibitors and epigenetic modifications as a novel strategy in renal cell carcinomaThe BAH domain of Rsc2 is a histone H3 binding domainSomatic SF3B1 mutation in myelodysplasia with ring sideroblastsEffects on survival of BAP1 and PBRM1 mutations in sporadic clear-cell renal-cell carcinoma: a retrospective analysis with independent validation.Adverse outcomes in clear cell renal cell carcinoma with mutations of 3p21 epigenetic regulators BAP1 and SETD2: a report by MSKCC and the KIRC TCGA research networkIntegrated molecular analysis of clear-cell renal cell carcinoma.
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P2860
Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma
description
2011 nî lūn-bûn
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2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Exome sequencing identifies fr ...... gene PBRM1 in renal carcinoma
@ast
Exome sequencing identifies fr ...... gene PBRM1 in renal carcinoma
@en
Exome sequencing identifies fr ...... gene PBRM1 in renal carcinoma
@en-gb
Exome sequencing identifies fr ...... gene PBRM1 in renal carcinoma
@nl
type
label
Exome sequencing identifies fr ...... gene PBRM1 in renal carcinoma
@ast
Exome sequencing identifies fr ...... gene PBRM1 in renal carcinoma
@en
Exome sequencing identifies fr ...... gene PBRM1 in renal carcinoma
@en-gb
Exome sequencing identifies fr ...... gene PBRM1 in renal carcinoma
@nl
prefLabel
Exome sequencing identifies fr ...... gene PBRM1 in renal carcinoma
@ast
Exome sequencing identifies fr ...... gene PBRM1 in renal carcinoma
@en
Exome sequencing identifies fr ...... gene PBRM1 in renal carcinoma
@en-gb
Exome sequencing identifies fr ...... gene PBRM1 in renal carcinoma
@nl
P2093
P2860
P50
P3181
P356
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P1476
Exome sequencing identifies fr ...... gene PBRM1 in renal carcinoma
@en
P2093
Adam Butler
Andrej Fischer
Chris Greenman
Chutima Subimerb
Claire Hardy
Danushka Galappaththige
David A Largaespada
David J Adams
David Jones
Graham Bignell
P2860
P2888
P304
P3181
P356
10.1038/NATURE09639
P407
P50
P577
2011-01-27T00:00:00Z
P5875
P6179
1009539954