Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis
about
The effect of OPA1 on mitochondrial Ca²⁺ signalingInducible proteolytic inactivation of OPA1 mediated by the OMA1 protease in mammalian cellsLRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1YME1L controls the accumulation of respiratory chain subunits and is required for apoptotic resistance, cristae morphogenesis, and cell proliferationChChd3, an inner mitochondrial membrane protein, is essential for maintaining crista integrity and mitochondrial functionQuantitation of mitochondrial dynamics by photolabeling of individual organelles shows that mitochondrial fusion is blocked during the Bax activation phase of apoptosisMitochondrial fission and fusion mediators, hFis1 and OPA1, modulate cellular senescenceLoss of mitochondrial protease OMA1 alters processing of the GTPase OPA1 and causes obesity and defective thermogenesis in micehNOA1 interacts with complex I and DAP3 and regulates mitochondrial respiration and apoptosisSIRT3 deacetylates and activates OPA1 to regulate mitochondrial dynamics during stressMff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cellsC11orf83, a mitochondrial cardiolipin-binding protein involved in bc1 complex assembly and supercomplex stabilizationEndoplasmic reticulum BIK initiates DRP1-regulated remodelling of mitochondrial cristae during apoptosis.The mitochondrial inner membrane protein mitofilin controls cristae morphologyOPA1 requires mitofusin 1 to promote mitochondrial fusionRoles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosisNew insights into the role of mitochondria in aging: mitochondrial dynamics and moreMINOS1 is a conserved component of mitofilin complexes and required for mitochondrial function and cristae organizationThe adipocyte-expressed forkhead transcription factor Foxc2 regulates metabolism through altered mitochondrial functionFission and selective fusion govern mitochondrial segregation and elimination by autophagyEndophilin B1 is required for the maintenance of mitochondrial morphologyMitochondrial morphology-emerging role in bioenergeticsMitoconfusion: noncanonical functioning of dynamism factors in static mitochondria of the heartMorphological control of mitochondrial bioenergeticsWhy mitochondria must fuse to maintain their genome integrityProhibitin 2 regulates the proliferation and lineage-specific differentiation of mouse embryonic stem cells in mitochondriaMitochondrial structure, function and dynamics are temporally controlled by c-MycInner membrane fusion mediates spatial distribution of axonal mitochondriaAlterations of mitochondrial dynamics allow retrograde propagation of locally initiated axonal insultsThe C. elegans Opa1 homologue EAT-3 is essential for resistance to free radicalsHuman wild-type full-length tau accumulation disrupts mitochondrial dynamics and the functions via increasing mitofusins.Kinetics and specificity of paternal mitochondrial elimination in Caenorhabditis elegans.Processing of Mgm1 by the rhomboid-type protease Pcp1 is required for maintenance of mitochondrial morphology and of mitochondrial DNA.A novel role of Mgm1p, a dynamin-related GTPase, in ATP synthase assembly and cristae formation/maintenanceWhat is the function of mitochondrial networks? A theoretical assessment of hypotheses and proposal for future researchMultifaceted role of prohibitin in cell survival and apoptosisHomozygous YME1L1 mutation causes mitochondriopathy with optic atrophy and mitochondrial network fragmentationA Novel Role for Progesterone Receptor Membrane Component 1 (PGRMC1): A Partner and Regulator of FerrochelataseThe i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fissionA novel prohibitin-binding compound induces the mitochondrial apoptotic pathway through NOXA and BIM upregulation
P2860
Q21135012-B9D544CC-7D57-455D-9A62-6705149430F0Q24293452-5132CF38-79B4-4819-B302-B0587CE7406FQ24301357-7834648D-DD74-4A6F-A973-2AAACDDB7F48Q24302280-E26C3513-9FAE-424A-97FD-E7D83BF03E19Q24307501-837A281B-ACCE-4519-A660-39E6B0B5F84BQ24307662-784B4D87-8153-40AC-9158-AE6E2BE8545DQ24307751-EC5F5A81-F872-4119-A435-D046192C5C8DQ24307976-67114C9D-9ABB-4BCA-BBF9-BFE55401118BQ24310217-F1884C35-0521-4AD8-B6A8-DCCCAEC352EAQ24313709-D926DD42-965D-4000-B8BB-E5F0E3DBCB05Q24315625-E3F240FA-77D9-46DC-A0B1-57EBA1B5855CQ24315727-67765C71-AEF2-4293-9C1F-3A73410BE4BDQ24529124-0FE7B2A1-DDEE-4B4F-A22D-6E8F3610469FQ24556571-1C757A19-952E-4D7F-BC71-AD650543307DQ24560014-9657234D-A459-4E7E-924A-DB06ED488218Q24562044-D400F501-7D2D-45B9-8DB6-87124B7A47F0Q24600600-3540F22C-4414-4FF7-8761-C0B5FB013F0EQ24609442-7064B12E-D152-4DCE-A658-052333814483Q24633432-A7EE9DE0-28DC-4AFC-AC00-B4EE718D560CQ24652230-27029758-D1EA-4B2B-8AB5-9112D3E48074Q24678157-6415EDF4-EACE-4852-8608-56DE3C2D238FQ26852770-D285C357-1B90-486A-85DE-77565AC47EEEQ27001001-589FCF33-20F8-44F2-A754-88D8DBDA16D5Q27006036-687325D9-856B-423C-82CE-EBE8872D31FDQ27022853-E2482FC5-7025-4889-8AF5-666573528087Q27301072-F40E7E3E-C222-4CC5-BEE1-718DAE288BE4Q27302245-6F1AD3EB-2AE1-451F-836D-C52B04C01F66Q27302292-C728CAD0-D67C-4567-831F-E963B31A4CBBQ27312652-D30840FB-516D-47B9-BC6D-2AF9D2B9609CQ27314280-5341B6FC-C7FC-4B50-9D4B-E07B106C63D1Q27320038-09F9921B-E6A9-41D9-9F87-7C32132666C1Q27331754-35D9423B-2AA7-401D-9DEB-E3638B57210FQ27933366-E8461269-48AA-415D-AD08-EFFC028B0BBEQ27939480-3577405B-944F-411E-99D9-71A86258A7A1Q28081668-D4C0E9B4-079F-487A-A858-42AB11030AE8Q28087391-BBB4FEE2-439F-45C9-8C0F-226F3C7176CBQ28117328-BCD5AA5C-2A97-4A5F-8D0E-6F0506ED20EEQ28118692-2BD1A113-B8DD-4D34-A98B-2BC5EA931856Q28235694-166938D5-753C-44E9-AD5B-3D97CBC9E123Q28269042-B83DAC17-B04E-40F0-AE17-6748F5079298
P2860
Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis
description
2003 nî lūn-bûn
@nan
2003 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մարտին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Loss of OPA1 perturbates the m ...... chrome c release and apoptosis
@ast
Loss of OPA1 perturbates the m ...... chrome c release and apoptosis
@en
Loss of OPA1 perturbates the m ...... chrome c release and apoptosis
@en-gb
Loss of OPA1 perturbates the m ...... chrome c release and apoptosis
@nl
type
label
Loss of OPA1 perturbates the m ...... chrome c release and apoptosis
@ast
Loss of OPA1 perturbates the m ...... chrome c release and apoptosis
@en
Loss of OPA1 perturbates the m ...... chrome c release and apoptosis
@en-gb
Loss of OPA1 perturbates the m ...... chrome c release and apoptosis
@nl
prefLabel
Loss of OPA1 perturbates the m ...... chrome c release and apoptosis
@ast
Loss of OPA1 perturbates the m ...... chrome c release and apoptosis
@en
Loss of OPA1 perturbates the m ...... chrome c release and apoptosis
@en-gb
Loss of OPA1 perturbates the m ...... chrome c release and apoptosis
@nl
P2093
P921
P3181
P356
P1476
Loss of OPA1 perturbates the m ...... chrome c release and apoptosis
@en
P2093
Annie Valette
Aurélien Olichon
Emmanuelle Guillou
Guy Lenaers
Laurent Baricault
Nicole Gas
Pascale Belenguer
P304
P3181
P356
10.1074/JBC.C200677200
P407
P577
2003-03-07T00:00:00Z