A novel prohibitin-binding compound induces the mitochondrial apoptotic pathway through NOXA and BIM upregulation
about
Spiro[pyrrolidine-3, 3´-oxindole] as potent anti-breast cancer compounds: Their design, synthesis, biological evaluation and cellular target identificationTargeting prohibitins induces apoptosis in acute myeloid leukemia cells.The prohibitin protein complex promotes mitochondrial stabilization and cell survival in hematologic malignanciesThe prohibitin-binding compound fluorizoline induces apoptosis in chronic lymphocytic leukemia cells through the upregulation of NOXA and synergizes with ibrutinib, 5-aminoimidazole-4-carboxamide riboside or venetoclax.Prohibitin-mediated mitochondrial ubiquitination during spermiogenesis in Chinese mitten crab Eriocheir sinensis.The prohibitin-binding compound fluorizoline induces apoptosis in chronic lymphocytic leukemia cells ex vivo but fails to prevent leukemia development in a murine model.Significance of prohibitin domain family in tumorigenesis and its implication in cancer diagnosis and treatment.
P2860
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P2860
A novel prohibitin-binding compound induces the mitochondrial apoptotic pathway through NOXA and BIM upregulation
description
2015 nî lūn-bûn
@nan
2015 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
A novel prohibitin-binding com ...... ough NOXA and BIM upregulation
@ast
A novel prohibitin-binding com ...... ough NOXA and BIM upregulation
@en
A novel prohibitin-binding com ...... ough NOXA and BIM upregulation
@nl
type
label
A novel prohibitin-binding com ...... ough NOXA and BIM upregulation
@ast
A novel prohibitin-binding com ...... ough NOXA and BIM upregulation
@en
A novel prohibitin-binding com ...... ough NOXA and BIM upregulation
@nl
prefLabel
A novel prohibitin-binding com ...... ough NOXA and BIM upregulation
@ast
A novel prohibitin-binding com ...... ough NOXA and BIM upregulation
@en
A novel prohibitin-binding com ...... ough NOXA and BIM upregulation
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
A novel prohibitin-binding com ...... ough NOXA and BIM upregulation
@en
P2093
Alba Pérez-Perarnau
Ana M Cosialls
Anne Korwitz
Claudia Mariela Palmeri
Cristina Moncunill-Massaguer
Diana M González-Gironès
Fernando Albericio
Gabriel Pons
Helena Pomares
Rodolfo Lavilla
P2860
P304
41750-41765
P3181
P356
10.18632/ONCOTARGET.6154
P407
P577
2015-12-01T00:00:00Z