Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways
about
APRIN is a cell cycle specific BRCA2-interacting protein required for genome integrity and a predictor of outcome after chemotherapy in breast cancerFANCG promotes formation of a newly identified protein complex containing BRCA2, FANCD2 and XRCC3Molecular pathogenesis and clinical management of Fanconi anemiaSusceptibility pathways in Fanconi's anemia and breast cancerHow the fanconi anemia pathway guards the genomeTip60 is required for DNA interstrand cross-link repair in the Fanconi anemia pathwayInterplay between Fanconi anemia and homologous recombination pathways in genome integrityThe Fanconi anemia pathway and DNA interstrand cross-link repairPathways for repairing and tolerating the spectrum of oxidative DNA lesionsRoles of brca2 (fancd1) in oocyte nuclear architecture, gametogenesis, gonad tumors, and genome stability in zebrafishInsights into Fanconi Anaemia from the structure of human FANCERegulation of monoubiquitinated PCNA by DUB autocleavageA comprehensive functional characterization of BRCA2 variants associated with Fanconi anemia using mouse ES cell-based assayFANCI protein binds to DNA and interacts with FANCD2 to recognize branched structuresCellular and molecular consequences of defective Fanconi anemia proteins in replication-coupled DNA repair: mechanistic insightsThe Fanconi anemia gene product FANCF is a flexible adaptor proteinHistone H2AX and Fanconi anemia FANCD2 function in the same pathway to maintain chromosome stabilityExpanded roles of the Fanconi anemia pathway in preserving genomic stabilityHallmarks of 'BRCAness' in sporadic cancersDNA IR-Double Strand Breaks (DSBs) and cellular response via ATMFanconi anemia complementation group FANCD2 protein serine 331 phosphorylation is important for fanconi anemia pathway function and BRCA2 interaction.RTEL1 contributes to DNA replication and repair and telomere maintenance.The role of the Fanconi anemia network in the response to DNA replication stress.Fanconi anemia proteins stabilize replication forks.The ubiquitin system, disease, and drug discovery.Fanconi anemia protein FANCD2 promotes immunoglobulin gene conversion and DNA repair through a mechanism related to homologous recombination.Significance of the Fanconi anemia FANCD2 protein in sporadic and metastatic human breast cancerFine mapping of 14q24.1 breast cancer susceptibility locusHuman HEL308 localizes to damaged replication forks and unwinds lagging strand structuresThe Fanconi anemia proteins FANCD2 and FANCJ interact and regulate each other's chromatin localization.Genetic disruption of both Fancc and Fancg in mice recapitulates the hematopoietic manifestations of Fanconi anemia.Fanconi anemia proteins are required to prevent accumulation of replication-associated DNA double-strand breaksGamma-radiation sensitivity and polymorphisms in RAD51L1 modulate glioma riskA unified analytic framework for prioritization of non-coding variants of uncertain significance in heritable breast and ovarian cancer.Human Mus81 and FANCB independently contribute to repair of DNA damage during replication.The phenotype of FancB-mutant mouse embryonic stem cells.The E3 ubiquitin ligase RAD18 regulates ubiquitylation and chromatin loading of FANCD2 and FANCISnm1B/Apollo functions in the Fanconi anemia pathway in response to DNA interstrand crosslinks.An activation force-based affinity measure for analyzing complex networks.Fanconi anemia pathway-deficient tumor cells are hypersensitive to inhibition of ataxia telangiectasia mutated.
P2860
Q24304176-BE03384D-D904-4B37-ADE2-CC5B961E4E54Q24307531-B2CF71B5-C3AA-4DCC-BCAD-70B7F4A471BFQ24621696-F27667B1-31B2-40E4-8DE9-895EE8A85CA4Q24628760-03E54A2C-FF3F-4972-93D1-CCC2E461B8E1Q24634556-1EFE768E-84EB-4825-97A5-7162A9F85D86Q24648613-3BDA628F-79EE-4A64-9AA8-503E7671FACAQ26753126-A6495E0E-402B-4512-93A2-7FD87DADB6EFQ26851561-6595D0B5-09AF-4CB4-8EAF-20A0F5D0C5F3Q26992194-6386995C-1D67-49D5-9ACE-B5D2AAB4208AQ27342643-0BA067AB-6A82-4267-876B-065EEE1B8BC8Q27643858-08EF248A-89DB-4871-B92B-9A32C148F0AAQ28115531-971108F5-585D-4154-841D-95E72039AED3Q28118199-58592907-11B6-46E5-84B0-A66BD3FB9E6CQ28250124-C015FE84-EB15-4B92-B3D3-0581A75316F1Q28252640-DA135617-2403-4743-A608-6C1048D1B2B7Q28272859-DD9707A6-CFBC-4352-9F70-5EB03A4D47A2Q28509626-5FE04775-EE03-4941-BC2D-D48CB1A4326BQ28749668-7515D712-45FD-4A76-8B17-08548D702E19Q29618825-5E226F63-6DD8-4D3E-808B-DF2B0102B621Q30225541-58123E9C-6282-4352-933A-63F0CF95FBF9Q30449304-AE5AF60A-F6C6-489C-96BC-9B2CCE8798C7Q30520031-A7DEB197-E9DD-4CC5-BCA3-32729C492DAEQ33347783-B67E55D6-C149-4039-9F63-C63337AAAD5AQ33368942-FF7FC0F8-7C70-43E9-88F7-6134959F2E69Q33384295-34DA2465-3DA5-444E-8460-047632C87C82Q33551464-FEE69F76-7DAE-4BCC-A53A-E5E04EC20664Q33882536-3E66603A-B472-454F-A6CB-E6394ABC190BQ34158088-8E04FC83-4155-4875-93F5-9573C01D162BQ34170371-03E9A50C-355A-42AA-8532-E9DB52D19C34Q34170774-2A3A8934-E3AD-4245-ABB1-2DE6E34D9102Q34282323-076A1001-AB4C-44D8-8609-A5C586E53306Q34301932-07C82E01-3CBF-4440-8744-FD678FD2A75FQ34310428-949AA197-E605-41F8-97FD-CC7D957498E5Q34521706-0B81F780-985E-4C1E-93EA-5433F006A029Q34695089-5680B024-8EEA-4E7E-A892-F93F27E63A73Q35028148-4624A05F-1A7C-4523-B976-7D875F1294C7Q35029423-07153D0A-2A34-4410-84B2-F0BA265D825DQ35030835-1EE300F0-4241-46F9-8127-4A32AB0A6232Q35551524-66E3B3DA-691C-42C6-B8EE-4D5765C61069Q35741383-999835C3-037B-4FE5-ACFE-816C99B22FC9
P2860
Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways
description
2004 nî lūn-bûn
@nan
2004 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways
@ast
Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways
@en
Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways
@en-gb
Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways
@nl
type
label
Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways
@ast
Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways
@en
Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways
@en-gb
Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways
@nl
prefLabel
Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways
@ast
Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways
@en
Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways
@en-gb
Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways
@nl
P2093
P50
P3181
P356
P1476
Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways
@en
P2093
Adelina Davies
Annette L Medhurst
Emily Witt
James B Wilson
James Hejna
Jean-Yves Masson
Johan P de Winter
Nigel J Jones
Robb Moses
Sahana Ananth
P304
P3181
P356
10.1093/HMG/DDH135
P407
P577
2004-06-15T00:00:00Z