about
Fanconi anemia complementation group A (FANCA) protein has intrinsic affinity for nucleic acids with preference for single-stranded formsCheckpoint signaling from a single DNA interstrand crosslinkDNA double-strand break repair pathway choice and cancerFANCI protein binds to DNA and interacts with FANCD2 to recognize branched structuresCellular and molecular consequences of defective Fanconi anemia proteins in replication-coupled DNA repair: mechanistic insightsA reduction of licensed origins reveals strain-specific replication dynamics in micePurification of FANCD2 sub-complexes.FANCJ helicase uniquely senses oxidative base damage in either strand of duplex DNA and is stimulated by replication protein A to unwind the damaged DNA substrate in a strand-specific manner.ATR activation and replication fork restart are defective in FANCM-deficient cells.Targeted inhibition of Replication Protein A reveals cytotoxic activity, synergy with chemotherapeutic DNA-damaging agents, and insight into cellular function.A concomitant loss of dormant origins and FANCC exacerbates genome instability by impairing DNA replication fork progression.Fanconi anemia signaling and Mus81 cooperate to safeguard development and crosslink repairRadiosensitization of mammary carcinoma cells by telomere homolog oligonucleotide pretreatment.The Fanconi anemia pathway and ICL repair: implications for cancer therapy.Damage-dependent regulation of MUS81-EME1 by Fanconi anemia complementation group A protein.Human Fanconi anemia complementation group a protein stimulates the 5' flap endonuclease activity of FEN1.DNA repair: from genome maintenance to biomarker and therapeutic target.Replication Protein A (RPA) deficiency activates the Fanconi anemia DNA repair pathway.Fanconi anemia proteins FANCD2 and FANCI exhibit different DNA damage responses during S-phaseThe Interferon Consensus Sequence Binding Protein (Icsbp/Irf8) Is Required for Termination of Emergency Granulopoiesis.A novel interplay between the Fanconi anemia core complex and ATR-ATRIP kinase during DNA cross-link repair.Increased Fanconi C expression contributes to the emergency granulopoiesis responseRecent insights into the molecular mechanisms involved in aging and the malignant transformation of adult stem/progenitor cells and their therapeutic implications.Cell-free Xenopus egg extracts for studying DNA damage response pathways.Cell resistance to the Cytolethal Distending Toxin involves an association of DNA repair mechanisms.FANCJ helicase operates in the Fanconi Anemia DNA repair pathway and the response to replicational stress.FANCD2 functions as a critical factor downstream of MiTF to maintain the proliferation and survival of melanoma cellsMaintenance of genome stability by Fanconi anemia proteins.RAD51C: a novel cancer susceptibility gene is linked to Fanconi anemia and breast cancer.Stress and DNA repair biology of the Fanconi anemia pathwayThe human oncoprotein and chromatin architectural factor DEK counteracts DNA replication stress.Reduced FANCD2 influences spontaneous SCE and RAD51 foci formation in uveal melanoma and Fanconi anaemia.Rad18 E3 ubiquitin ligase activity mediates Fanconi anemia pathway activation and cell survival following DNA Topoisomerase 1 inhibition.Fanconi anemia: a paradigm of discovering molecular pathways from patients.Hypoxic stress facilitates acute activation and chronic downregulation of fanconi anemia proteins.Monoketone analogs of curcumin, a new class of Fanconi anemia pathway inhibitors.Fanconi anemia proteins and endogenous stresses.Stat3 and CCAAT enhancer-binding protein β (C/ebpβ) activate Fanconi C gene transcription during emergency granulopoiesis.TP53 Haploinsufficiency Rescues Emergency Granulopoiesis in FANCC-/- Mice.
P2860
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P2860
description
2008 nî lūn-bûn
@nan
2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Fanconi anemia proteins stabilize replication forks.
@ast
Fanconi anemia proteins stabilize replication forks.
@en
type
label
Fanconi anemia proteins stabilize replication forks.
@ast
Fanconi anemia proteins stabilize replication forks.
@en
prefLabel
Fanconi anemia proteins stabilize replication forks.
@ast
Fanconi anemia proteins stabilize replication forks.
@en
P2093
P2860
P1433
P1476
Fanconi anemia proteins stabilize replication forks.
@en
P2093
Jean Gautier
Lily Chien Wang
Maureen Elizabeth Hoatlin
Stacie Stone
P2860
P304
P356
10.1016/J.DNAREP.2008.08.005
P577
2008-09-25T00:00:00Z