MAGE-A4 interacts with the liver oncoprotein gankyrin and suppresses its tumorigenic activity
about
MageA2 restrains cellular senescence by targeting the function of PMLIV/p53 axis at the PML-NBsMAGE-A1 interacts with adaptor SKIP and the deacetylase HDAC1 to repress transcriptionA cleaved form of MAGE-A4 binds to Miz-1 and induces apoptosis in human cellsThe ankyrin repeat as molecular architecture for protein recognitionThe crystal structure of gankyrin, an oncoprotein found in complexes with cyclin-dependent kinase 4, a 19 S proteasomal ATPase regulator, and the tumor suppressors Rb and p53Cancer/testis antigens, gametogenesis and cancerCoordinated activation of candidate proto-oncogenes and cancer testes antigens via promoter demethylation in head and neck cancer and lung cancerTumor subtype-specific cancer-testis antigens as potential biomarkers and immunotherapeutic targets for cancers.Frequent MAGE mutations in human melanomaAn overview of cancer/testis antigens expression in classical Hodgkin's lymphoma (cHL) identifies MAGE-A family and MAGE-C1 as the most frequently expressed antigens in a set of Brazilian cHL patients.Expression of cancer-testis (CT) antigens in placenta.Loss of hepatic NF-kappa B activity enhances chemical hepatocarcinogenesis through sustained c-Jun N-terminal kinase 1 activationExpression patterns of cancer-testis antigens in human embryonic stem cells and their cell derivatives indicate lineage tracksStructures of Two Melanoma-Associated Antigens Suggest Allosteric Regulation of Effector Binding.Cancer testis antigens--their importance in immunotherapy and in the early detection of cancer.Myeloid-derived suppressor cells enhance the expression of melanoma-associated antigen A4 in a Lewis lung cancer murine modelCoping with stress: multiple ways to activate p53.A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis.Analysis of expression profiles of MAGE-A antigens in oral squamous cell carcinoma cell linesCancer-germline antigen vaccines and epigenetic enhancers: future strategies for cancer treatment.The biology of cancer testis antigens: putative function, regulation and therapeutic potentialSperm protein 17: clinical relevance of a cancer/testis antigen, from contraception to cancer immunotherapy, and beyond.Cancer testes antigens in breast cancer: biological role, regulation, and therapeutic applicability.Cancer testis antigens: a novel target in lung cancer.Cancer/testis antigens expression and autologous serological response in a set of Brazilian non-Hodgkin's lymphoma patients.Discovery of multiple interacting partners of gankyrin, a proteasomal chaperone and an oncoprotein--evidence for a common hot spot site at the interface and its functional relevance.Effects of CT-Xp gene knock down in melanoma cell lines.Adriamycin enhances proteasome-mediated generation of the proapoptotic processed form of MAGE-A4 in hepatoma cells.Identification of two novel HLA-A*0201-restricted CTL epitopes derived from MAGE-A4.Overexpression of a new gene P28GANK confers multidrug resistance of gastric cancer cells.Gankyrin oncoprotein overexpression as a critical factor for tumor growth in human esophageal squamous cell carcinoma and its clinical significance.p53-independent pRB degradation contributes to a drug-induced apoptosis in AGS cells.Consequences of point mutations in melanoma-associated antigen 4 (MAGE-A4) protein: Insights from structural and biophysical studiesDissection of protein-protein interaction and CDK4 inhibition in the oncogenic versus tumor suppressing functions of gankyrin and P16.Cancer/testis antigen MAGE-A4 expression pattern differs in epithelial skin tumors of organ-transplant recipients and immunocompetent patients.
P2860
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P2860
MAGE-A4 interacts with the liver oncoprotein gankyrin and suppresses its tumorigenic activity
description
2003 nî lūn-bûn
@nan
2003 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մարտին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
MAGE-A4 interacts with the liv ...... esses its tumorigenic activity
@ast
MAGE-A4 interacts with the liv ...... esses its tumorigenic activity
@en
MAGE-A4 interacts with the liv ...... esses its tumorigenic activity
@en-gb
MAGE-A4 interacts with the liv ...... esses its tumorigenic activity
@nl
type
label
MAGE-A4 interacts with the liv ...... esses its tumorigenic activity
@ast
MAGE-A4 interacts with the liv ...... esses its tumorigenic activity
@en
MAGE-A4 interacts with the liv ...... esses its tumorigenic activity
@en-gb
MAGE-A4 interacts with the liv ...... esses its tumorigenic activity
@nl
prefLabel
MAGE-A4 interacts with the liv ...... esses its tumorigenic activity
@ast
MAGE-A4 interacts with the liv ...... esses its tumorigenic activity
@en
MAGE-A4 interacts with the liv ...... esses its tumorigenic activity
@en-gb
MAGE-A4 interacts with the liv ...... esses its tumorigenic activity
@nl
P2093
P2860
P3181
P356
P1476
MAGE-A4 interacts with the liv ...... esses its tumorigenic activity
@en
P2093
Hiroaki Higashitsuji
Jun Fujita
Katsuhiko Itoh
Kohsuke Nonoguchi
R John Mayer
Simon Dawson
Toshiharu Sakurai
Toshikazu Nagao
P2860
P304
P3181
P356
10.1074/JBC.M206104200
P407
P577
2003-03-21T00:00:00Z