Dissection of protein-protein interaction and CDK4 inhibition in the oncogenic versus tumor suppressing functions of gankyrin and P16.
about
The other side of the coin: the tumor-suppressive aspect of oncogenes and the oncogenic aspect of tumor-suppressive genes, such as those along the CCND-CDK4/6-RB axisNovel p16 binding peptide development for p16-overexpressing cancer cell detection using phage display.Familial melanoma-associated mutations in p16 uncouple its tumor-suppressor functionsGankyrin regulates cell signaling network.Biological regulation via ankyrin repeat folding.Contributions of conserved TPLH tetrapeptides to the conformational stability of ankyrin repeat proteins.C-terminal deletion of leucine-rich repeats from YopM reveals a heterogeneous distribution of stability in a cooperatively folded protein.Upregulation of PSMD10 caused by the JMJD2A histone demethylase.The study of pH-dependent stability shows that the TPLH-mediated hydrogen-bonding network is important for the conformation and stability of human gankyrin.Predicting repeat protein folding kinetics from an experimentally determined folding energy landscape.
P2860
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P2860
Dissection of protein-protein interaction and CDK4 inhibition in the oncogenic versus tumor suppressing functions of gankyrin and P16.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Dissection of protein-protein ...... functions of gankyrin and P16.
@en
type
label
Dissection of protein-protein ...... functions of gankyrin and P16.
@en
prefLabel
Dissection of protein-protein ...... functions of gankyrin and P16.
@en
P2093
P2860
P1476
Dissection of protein-protein ...... functions of gankyrin and P16.
@en
P2093
Anjali Mahajan
Christopher M Weghorst
Chunhua Yuan
P2860
P304
P356
10.1016/J.JMB.2007.08.038
P407
P577
2007-08-22T00:00:00Z