The fast-mobility isoform of mouse Mcl-1 is a mitochondrial matrix-localized protein with attenuated anti-apoptotic activity
about
Naturally Occurring Isothiocyanates Exert Anticancer Effects by Inhibiting Deubiquitinating EnzymesMultiple functions of BCL-2 family proteins.Mitochondrion-dependent N-terminal processing of outer membrane Mcl-1 protein removes an essential Mule/Lasu1 protein-binding site.Transcriptomic profiles of aging in purified human immune cellsUV Differentially Induces Oxidative Stress, DNA Damage and Apoptosis in BCR-ABL1-Positive Cells Sensitive and Resistant to Imatinib.Anti-apoptotic MCL-1 localizes to the mitochondrial matrix and couples mitochondrial fusion to respiration.Delving deeper: MCL-1's contributions to normal and cancer biology.Enhanced stability of Mcl1, a prosurvival Bcl2 relative, blunts stress-induced apoptosis, causes male sterility, and promotes tumorigenesis.Bcl-2 protein family expression pattern determines synergistic pro-apoptotic effects of BH3 mimetics with hemisynthetic cardiac glycoside UNBS1450 in acute myeloid leukemia.Multipolar functions of BCL-2 proteins link energetics to apoptosisThe tangled circuitry of metabolism and apoptosis.Programming cancer cells for high expression levels of Mcl1.Regulation of mitochondrial nutrient and energy metabolism by BCL-2 family proteins.HCMV activation of ERK-MAPK drives a multi-factorial response promoting the survival of infected myeloid progenitors.Inhibition of MCL-1 by obatoclax sensitizes Sp2/0-Ag14 hybridoma cells to glutamine deprivation-induced apoptosis.Maritoclax and dinaciclib inhibit MCL-1 activity and induce apoptosis in both a MCL-1-dependent and -independent manner.The N-terminal helix of Bcl-xL targets mitochondria.Selectively targeting Mcl-1 for the treatment of acute myelogenous leukemia and solid tumors.Does N-terminal processing of Mcl-1 occur at mitochondrial outer membrane or matrix?MYC and MCL1 Cooperatively Promote Chemotherapy-Resistant Breast Cancer Stem Cells via Regulation of Mitochondrial Oxidative Phosphorylation.Fibroblast Growth Factor Receptor Inhibition induces loss of matrix MCL1 and necrosis in Cholangiocarcinoma.
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P2860
The fast-mobility isoform of mouse Mcl-1 is a mitochondrial matrix-localized protein with attenuated anti-apoptotic activity
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The fast-mobility isoform of m ...... nuated anti-apoptotic activity
@ast
The fast-mobility isoform of m ...... nuated anti-apoptotic activity
@en
The fast-mobility isoform of m ...... nuated anti-apoptotic activity
@en-gb
The fast-mobility isoform of m ...... nuated anti-apoptotic activity
@nl
type
label
The fast-mobility isoform of m ...... nuated anti-apoptotic activity
@ast
The fast-mobility isoform of m ...... nuated anti-apoptotic activity
@en
The fast-mobility isoform of m ...... nuated anti-apoptotic activity
@en-gb
The fast-mobility isoform of m ...... nuated anti-apoptotic activity
@nl
prefLabel
The fast-mobility isoform of m ...... nuated anti-apoptotic activity
@ast
The fast-mobility isoform of m ...... nuated anti-apoptotic activity
@en
The fast-mobility isoform of m ...... nuated anti-apoptotic activity
@en-gb
The fast-mobility isoform of m ...... nuated anti-apoptotic activity
@nl
P2860
P921
P1433
P1476
The fast-mobility isoform of m ...... nuated anti-apoptotic activity
@en
P2093
Chi-Ruei Huang
Hsin-Fang Yang-Yen
P2860
P304
P356
10.1016/J.FEBSLET.2010.07.013
P407
P577
2010-08-04T00:00:00Z