Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1
about
Monosaccharide digitoxin derivative sensitize human non-small cell lung cancer cells to anoikis through Mcl-1 proteasomal degradationRole of bile salt in regulating Mcl-1 phosphorylation and chemoresistance in hepatocellular carcinoma cellsPrevention of cytokine withdrawal-induced apoptosis by Mcl-1 requires interaction between Mcl-1 and BimCaveolin-1 regulates Mcl-1 stability and anoikis in lung carcinoma cellsMCL-1 is a stress sensor that regulates autophagy in a developmentally regulated mannerThe fast-mobility isoform of mouse Mcl-1 is a mitochondrial matrix-localized protein with attenuated anti-apoptotic activityTaspase1 functions as a non-oncogene addiction protease that coordinates cancer cell proliferation and apoptosisG-CSF improves murine G6PC3-deficient neutrophil function by modulating apoptosis and energy homeostasisGlucose metabolism attenuates p53 and Puma-dependent cell death upon growth factor deprivationA syndrome with congenital neutropenia and mutations in G6PC3AKT/PKB signaling: navigating downstreamMitochondrial Dysfunction in Alzheimer's Disease and the Rationale for Bioenergetics Based TherapiesAkt isoforms in vascular diseaseRegulation of the intrinsic apoptosis pathway by reactive oxygen speciesTargeting Mcl-1 for the therapy of cancerModulation of apoptosis sensitivity through the interplay with autophagic and proteasomal degradation pathwaysExploitation of the Apoptosis-Primed State of MYCN-Amplified Neuroblastoma to Develop a Potent and Specific Targeted Therapy CombinationChronic Deletion and Acute Knockdown of Parkin Have Differential Responses to Acetaminophen-induced Mitophagy and Liver Injury in MiceCell biology. Metabolic control of cell deathA dual-color fluorescence-based platform to identify selective inhibitors of Akt signalingMcl-1 is a key regulator of apoptosis resistance in Chlamydia trachomatis-infected cellsThr 163 phosphorylation causes Mcl-1 stabilization when degradation is independent of the adjacent GSK3-targeted phosphodegron, promoting drug resistance in cancerInhibitory phosphorylation of GSK-3 by CaMKII couples depolarization to neuronal survivalMcl-1 downregulation by pro-inflammatory cytokines and palmitate is an early event contributing to β-cell apoptosisModulation of GSK-3β activity in Venezuelan equine encephalitis virus infectionRegulation of protein stability by GSK3 mediated phosphorylation.Regulation of c-Myc Protein Abundance by a Protein Phosphatase 2A-Glycogen Synthase Kinase 3β-Negative Feedback Pathway.GSK-3: Functional Insights from Cell Biology and Animal Models.Genomic duplication and overexpression of TJP2/ZO-2 leads to altered expression of apoptosis genes in progressive nonsyndromic hearing loss DFNA51.Ectodomain shedding of EGFR ligands and TNFR1 dictates hepatocyte apoptosis during fulminant hepatitis in miceSerum and glucocorticoid-regulated kinase 1 regulates neutrophil clearance during inflammation resolution.GSK3β controls epithelial-mesenchymal transition and tumor metastasis by CHIP-mediated degradation of SlugSurvival signaling by C-RAF: mitochondrial reactive oxygen species and Ca2+ are critical targetsPhosphatidylinositol 3-kinase signaling in proliferating cells maintains an anti-apoptotic transcriptional program mediated by inhibition of FOXO and non-canonical activation of NFkappaB transcription factorsCytoplasmic signaling in the control of mitochondrial uproar?Involvment of cytosolic and mitochondrial GSK-3beta in mitochondrial dysfunction and neuronal cell death of MPTP/MPP-treated neuronsThe Bcl-2/xL inhibitor ABT-263 increases the stability of Mcl-1 mRNA and protein in hepatocellular carcinoma cells.Is Akt the "Warburg kinase"?-Akt-energy metabolism interactions and oncogenesis.A20 Inhibits β-Cell Apoptosis by Multiple Mechanisms and Predicts Residual β-Cell Function in Type 1 Diabetes.Glycogen synthase kinase-3β is involved in ligand-dependent activation of transcription and cellular localization of the glucocorticoid receptor.
P2860
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P248
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P2860
Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1
description
2006 nî lūn-bûn
@nan
2006 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մարտին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Glycogen synthase kinase-3 reg ...... is by destabilization of MCL-1
@ast
Glycogen synthase kinase-3 reg ...... is by destabilization of MCL-1
@en
Glycogen synthase kinase-3 reg ...... is by destabilization of MCL-1
@en-gb
Glycogen synthase kinase-3 reg ...... is by destabilization of MCL-1
@nl
type
label
Glycogen synthase kinase-3 reg ...... is by destabilization of MCL-1
@ast
Glycogen synthase kinase-3 reg ...... is by destabilization of MCL-1
@en
Glycogen synthase kinase-3 reg ...... is by destabilization of MCL-1
@en-gb
Glycogen synthase kinase-3 reg ...... is by destabilization of MCL-1
@nl
prefLabel
Glycogen synthase kinase-3 reg ...... is by destabilization of MCL-1
@ast
Glycogen synthase kinase-3 reg ...... is by destabilization of MCL-1
@en
Glycogen synthase kinase-3 reg ...... is by destabilization of MCL-1
@en-gb
Glycogen synthase kinase-3 reg ...... is by destabilization of MCL-1
@nl
P2093
P921
P3181
P1433
P1476
Glycogen synthase kinase-3 reg ...... is by destabilization of MCL-1
@en
P2093
Allan S Wagman
Céline Charvet
Emmanuel Dejardin
Ulrich Maurer
P304
P3181
P356
10.1016/J.MOLCEL.2006.02.009
P407
P577
2006-03-17T00:00:00Z