Evidence for core exosome independent function of the nuclear exoribonuclease Rrp6p.
about
A link between nuclear RNA surveillance, the human exosome and RNA polymerase II transcriptional terminationDis3-like 1: a novel exoribonuclease associated with the human exosomeThe C-terminal region of the exosome-associated protein Rrp47 is specifically required for box C/D small nucleolar RNA 3'-maturationThe N-terminal PIN domain of the exosome subunit Rrp44 harbors endonuclease activity and tethers Rrp44 to the yeast core exosomeTRAMP complex enhances RNA degradation by the nuclear exosome component Rrp6Rrp6: Integrated roles in nuclear RNA metabolism and transcription terminationThreading the barrel of the RNA exosomeProcessing of preribosomal RNA in Saccharomyces cerevisiaeActivities of human RRP6 and structure of the human RRP6 catalytic domainRRP6 from Trypanosoma brucei: crystal structure of the catalytic domain, association with EAP3 and activity towards structured and non-structured RNA substratesCrystal structure of an RNA-bound 11-subunit eukaryotic exosome complexStructure of an Rrp6–RNA exosome complex bound to poly(A) RNARNA degradation paths in a 12-subunit nuclear exosome complexAssembly of the yeast exoribonuclease Rrp6 with its associated cofactor Rrp47 occurs in the nucleus and is critical for the controlled expression of Rrp47Nuclear mRNA quality control in yeast is mediated by Nrd1 co-transcriptional recruitment, as revealed by the targeting of Rho-induced aberrant transcripts.Exosome Cofactors Connect Transcription Termination to RNA Processing by Guiding Terminated Transcripts to the Appropriate Exonuclease within the Nuclear ExosomeThe essential nucleolar yeast protein Nop8p controls the exosome function during 60S ribosomal subunit maturationThe Sm complex is required for the processing of non-coding RNAs by the exosomeCore exosome-independent roles for Rrp6 in cell cycle progression.The CCR4-NOT complex physically and functionally interacts with TRAMP and the nuclear exosome.Interdependent nucleocytoplasmic trafficking and interactions of Dis3 with Rrp6, the core exosome and importin-alpha3The crystal structure of Mtr4 reveals a novel arch domain required for rRNA processingThe exozyme model: a continuum of functionally distinct complexes.Progenitor function in self-renewing human epidermis is maintained by the exosome.Comparison of the yeast and human nuclear exosome complexes.Drosophila melanogaster Dis3 N-terminal domains are required for ribonuclease activities, nuclear localization and exosome interactionsThe ribonuclease Dis3 is an essential regulator of the developmental transcriptome.Unique properties of the Mtr4p-poly(A) complex suggest a role in substrate targeting.A novel member of the RNase D exoribonuclease family functions in mitochondrial guide RNA metabolism in Trypanosoma bruceiThe exosome cofactor Rrp47 is critical for the stability and normal expression of its associated exoribonuclease Rrp6 in Saccharomyces cerevisiae.Structural components and architectures of RNA exosomesArabidopsis RRP6L1 and RRP6L2 function in FLOWERING LOCUS C silencing via regulation of antisense RNA synthesis.Pronounced and extensive microtubule defects in a Saccharomyces cerevisiae DIS3 mutant.Dis3- and exosome subunit-responsive 3' mRNA instability elementsImmature large ribosomal subunits containing the 7S pre-rRNA can engage in translation in Saccharomyces cerevisiaeAir proteins control differential TRAMP substrate specificity for nuclear RNA surveillanceExo- and endoribonucleolytic activities of yeast cytoplasmic and nuclear RNA exosomes are dependent on the noncatalytic core and central channel.Transcriptome-wide analysis of alternative routes for RNA substrates into the exosome complexExtensive degradation of RNA precursors by the exosome in wild-type cells.Nuclear RNA surveillance: role of TRAMP in controlling exosome specificity.
P2860
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P2860
Evidence for core exosome independent function of the nuclear exoribonuclease Rrp6p.
description
2008 nî lūn-bûn
@nan
2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Evidence for core exosome independent function of the nuclear exoribonuclease Rrp6p.
@ast
Evidence for core exosome independent function of the nuclear exoribonuclease Rrp6p.
@en
Evidence for core exosome independent function of the nuclear exoribonuclease Rrp6p.
@nl
type
label
Evidence for core exosome independent function of the nuclear exoribonuclease Rrp6p.
@ast
Evidence for core exosome independent function of the nuclear exoribonuclease Rrp6p.
@en
Evidence for core exosome independent function of the nuclear exoribonuclease Rrp6p.
@nl
prefLabel
Evidence for core exosome independent function of the nuclear exoribonuclease Rrp6p.
@ast
Evidence for core exosome independent function of the nuclear exoribonuclease Rrp6p.
@en
Evidence for core exosome independent function of the nuclear exoribonuclease Rrp6p.
@nl
P2860
P356
P1476
Evidence for core exosome independent function of the nuclear exoribonuclease Rrp6p.
@en
P2093
J Scott Butler
Kevin P Callahan
P2860
P304
P356
10.1093/NAR/GKN743
P407
P577
2008-12-01T00:00:00Z