XRCC1 is specifically associated with poly(ADP-ribose) polymerase and negatively regulates its activity following DNA damage - Test2 - elhamkhani - TriplyDB

XRCC1 is specifically associated with poly(ADP-ribose) polymerase and negatively regulates its activity following DNA damage

XRCC1 is specifically associated with poly(ADP-ribose) polymerase and negatively regulates its activity following DNA damage

http://www.wikidata.org/entity/Q24522502

about

3-Methyladenine-DNA glycosylase (MPG protein) interacts with human RAD23 proteins The role of poly(ADP-ribose) in the DNA damage signaling network Smoking modifies the relationship between XRCC1 haplotypes and HPV16-negative head and neck squamous cell carcinoma Function of BRCA1 in the DNA damage response is mediated by ADP-ribosylation Human RECQL5 participates in the removal of endogenous DNA damage Poly(ADP-ribose)-dependent regulation of Snail1 protein stability Opposing roles of mitochondrial and nuclear PARP1 in the regulation of mitochondrial and nuclear DNA integrity: implications for the regulation of mitochondrial function Cooperation of the Cockayne syndrome group B protein and poly(ADP-ribose) polymerase 1 in the response to oxidative stress.PARP-1 transcriptional activity is regulated by sumoylation upon heat shock Domain specific interaction in the XRCC1-DNA polymerase beta complex Mitochondrial DNA ligase III function is independent of Xrcc1.Structure of an XRCC1 BRCT domain: a new protein-protein interaction module XRCC1 coordinates the initial and late stages of DNA abasic site repair through protein-protein interactions Early embryonic lethality in PARP-1 Atm double-mutant mice suggests a functional synergy in cell proliferation during development A cell cycle-specific requirement for the XRCC1 BRCT II domain during mammalian DNA strand break repair Translocation of XRCC1 and DNA ligase IIIalpha from centrosomes to chromosomes in response to DNA damage in mitotic human cells XRCC1 co-localizes and physically interacts with PCNA Functional Evolution of BRCT Domains from Binding DNA to Protein PARP1 suppresses homologous recombination events in mice in vivo BRCT domains: easy as one, two, three Molecular mechanism of DNA deadenylation by the neurological disease protein aprataxin PARP inhibition versus PARP-1 silencing: different outcomes in terms of single-strand break repair and radiation susceptibility Physical and functional interaction between DNA ligase IIIalpha and poly(ADP-Ribose) polymerase 1 in DNA single-strand break repair Regulation of poly(ADP-ribose) polymerase 1 activity by the phosphorylation state of the nuclear NAD biosynthetic enzyme NMN adenylyl transferase 1 Genetic cooperation between the Werner syndrome protein and poly(ADP-ribose) polymerase-1 in preventing chromatid breaks, complex chromosomal rearrangements, and cancer in mice Poly(ADP-ribose) polymerase (PARP-1) is not involved in DNA double-strand break recovery Human base excision repair enzymes apurinic/apyrimidinic endonuclease1 (APE1), DNA polymerase beta and poly(ADP-ribose) polymerase 1: interplay between strand-displacement DNA synthesis and proofreading exonuclease activity APE1 overexpression in XRCC1-deficient cells complements the defective repair of oxidative single strand breaks but increases genomic instability XRCC1 is required for DNA single-strand break repair in human cells.Poly(ADP-RIBOSE) polymerase-1 (Parp-1) antagonizes topoisomerase I-dependent recombination stimulation by P53 XRCC1 is phosphorylated by DNA-dependent protein kinase in response to DNA damage Inhibition of poly (ADP-ribose) polymerase activates ATM which is required for subsequent homologous recombination repair Functions of PARylation in DNA Damage Repair Pathways XRCC1 and OGG1 Gene Polymorphisms and Breast Cancer: A Systematic Review of Literature Trial watch - inhibiting PARP enzymes for anticancer therapy Role of Biomarkers in the Development of PARP Inhibitors Homologous Recombination Deficiency: Exploiting the Fundamental Vulnerability of Ovarian Cancer Beyond Breast and Ovarian Cancers: PARP Inhibitors for BRCA Mutation-Associated and BRCA-Like Solid Tumors Pleiotropic cellular functions of PARP1 in longevity and aging: genome maintenance meets inflammation Structure and function of the ARH family of ADP-ribosyl-acceptor hydrolases

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XRCC1 is specifically associated with poly(ADP-ribose) polymerase and negatively regulates its activity following DNA damage

http://www.wikidata.org/entity/Q24522502

description

1998 nî lūn-bûn

@nan

1998 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

1998 թվականի հունիսին հրատարակված գիտական հոդված

@hy

1998年の論文

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1998年論文

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1998年論文

@zh-hant

1998年論文

@zh-hk

1998年論文

@zh-mo

1998年論文

@zh-tw

1998年论文

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name

XRCC1 is specifically associat ...... activity following DNA damage

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XRCC1 is specifically associat ...... activity following DNA damage

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XRCC1 is specifically associat ...... activity following DNA damage

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XRCC1 is specifically associat ...... activity following DNA damage

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XRCC1 is specifically associat ...... activity following DNA damage

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XRCC1 is specifically associat ...... activity following DNA damage

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XRCC1 is specifically associat ...... activity following DNA damage

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Molecular and Cellular Biology

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C Niedergang

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G de Murcia

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J Menissier-de Murcia

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M Masson

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P2860

Characterization of the XRCC1-DNA ligase III complex in vitro and its absence from mutant hamster cells

Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1).

Reconstitution of DNA base excision-repair with purified human proteins: interaction between DNA polymerase beta and the XRCC1 protein

An interaction between the mammalian DNA repair protein XRCC1 and DNA ligase III

Molecular cloning of the human XRCC1 gene, which corrects defective DNA strand break repair and sister chromatid exchange

An alternative splicing event which occurs in mouse pachytene spermatocytes generates a form of DNA ligase III with distinct biochemical properties that may function in meiotic recombination

Molecular cloning and expression of human cDNAs encoding a novel DNA ligase IV and DNA ligase III, an enzyme active in DNA repair and recombination

Mammalian Ras interacts directly with the serine/threonine kinase Raf

The two-hybrid system: a method to identify and clone genes for proteins that interact with a protein of interest

XRCC1 protein interacts with one of two distinct forms of DNA ligase III

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580276

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10.1128/MCB.18.6.3563

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6

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18

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9584196

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108937

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