Stable X chromosome inactivation involves the PRC1 Polycomb complex and requires histone MACROH2A1 and the CULLIN3/SPOP ubiquitin E3 ligase - Test2 - elhamkhani - TriplyDB

Stable X chromosome inactivation involves the PRC1 Polycomb complex and requires histone MACROH2A1 and the CULLIN3/SPOP ubiquitin E3 ligase

Stable X chromosome inactivation involves the PRC1 Polycomb complex and requires histone MACROH2A1 and the CULLIN3/SPOP ubiquitin E3 ligase

http://www.wikidata.org/entity/Q24529056

about

Cullin-RING ubiquitin ligases: global regulation and activation cycles The histone variant macroH2A1 marks repressed autosomal chromatin, but protects a subset of its target genes from silencing Tumor-suppressor role for the SPOP ubiquitin ligase in signal-dependent proteolysis of the oncogenic co-activator SRC-3/AIB1 The Cul3/Klhdc5 E3 ligase regulates p60/katanin and is required for normal mitosis in mammalian cells Ubiquitylation-dependent localization of PLK1 in mitosis Weak but uniform enrichment of the histone variant macroH2A1 along the inactive X chromosome Structure and E3-ligase activity of the Ring-Ring complex of polycomb proteins Bmi1 and Ring1b macroH2A1 histone variant represses rDNA transcription Ubiquitin-specific proteases 7 and 11 modulate Polycomb regulation of the INK4a tumour suppressor Structure of a Bmi-1-Ring1B polycomb group ubiquitin ligase complex SPOP promotes tumorigenesis by acting as a key regulatory hub in kidney cancer A novel role for Xist RNA in the formation of a repressive nuclear compartment into which genes are recruited when silenced The Cullin3 ubiquitin ligase functions as a Nedd8-bound heterodimer Expression and functionality of histone H2A variants in cancer Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases Is there more to BARD1 than BRCA1?Bood POZ containing gene type 2 is a human counterpart of yeast Btb3p and promotes the degradation of terminal deoxynucleotidyltransferase Switches, excitable responses and oscillations in the Ring1B/Bmi1 ubiquitination system Pcif1 modulates Pdx1 protein stability and pancreatic β cell function and survival in mice Constitutive turnover of cyclin E by Cul3 maintains quiescence Ubiquitination and degradation of ribonucleotide reductase M1 by the polycomb group proteins RNF2 and Bmi1 and cellular response to gemcitabine MacroH2A histone variants act as a barrier upon reprogramming towards pluripotency Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved Mouse polycomb proteins bind differentially to methylated histone H3 and RNA and are enriched in facultative heterochromatin Evolution from XIST-independent to XIST-controlled X-chromosome inactivation: epigenetic modifications in distantly related mammals Polycomb silencers control cell fate, development and cancer Histone variant macroH2A confers resistance to nuclear reprogramming.Transcription of the rat testis-specific Rtdpoz-T1 and -T2 retrogenes during embryo development: co-transcription and frequent exonisation of transposable element sequences.A ubiquitin ligase complex regulates caspase activation during sperm differentiation in Drosophila.Ubiquitin E3 ligase Ring1b/Rnf2 of polycomb repressive complex 1 contributes to stable maintenance of mouse embryonic stem cells The Polycomb protein and E3 ubiquitin ligase Ring1B harbors an IRES in its highly conserved 5' UTR Histone variants: emerging players in cancer biology.The histone variant MacroH2A1 regulates target gene expression in part by recruiting the transcriptional coregulator PELP1.The U2AF1S34F mutation induces lineage-specific splicing alterations in myelodysplastic syndromes.Histone variant macroH2A1 deletion in mice causes female-specific steatosis.The histone H2A variant macroH2A1 does not localize to the centrosome.The Mbd1-Atf7ip-Setdb1 pathway contributes to the maintenance of X chromosome inactivation.X chromosome inactivation and differentiation occur readily in ES cells doubly-deficient for macroH2A1 and macroH2A2.QKI-mediated alternative splicing of the histone variant MacroH2A1 regulates cancer cell proliferation Association of BMI1 with polycomb bodies is dynamic and requires PRC2/EZH2 and the maintenance DNA methyltransferase DNMT1

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P2860

Stable X chromosome inactivation involves the PRC1 Polycomb complex and requires histone MACROH2A1 and the CULLIN3/SPOP ubiquitin E3 ligase

http://www.wikidata.org/entity/Q24529056

description

2005 nî lūn-bûn

@nan

2005 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի մայիսին հրատարակված գիտական հոդված

@hy

2005年の論文

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2005年論文

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2005年論文

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2005年論文

@zh-hk

2005年論文

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2005年論文

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2005年论文

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name

Stable X chromosome inactivati ...... LLIN3/SPOP ubiquitin E3 ligase

@ast

Stable X chromosome inactivati ...... LLIN3/SPOP ubiquitin E3 ligase

@en

Stable X chromosome inactivati ...... LLIN3/SPOP ubiquitin E3 ligase

@en-gb

Stable X chromosome inactivati ...... LLIN3/SPOP ubiquitin E3 ligase

@nl

type

label

Stable X chromosome inactivati ...... LLIN3/SPOP ubiquitin E3 ligase

@ast

Stable X chromosome inactivati ...... LLIN3/SPOP ubiquitin E3 ligase

@en

Stable X chromosome inactivati ...... LLIN3/SPOP ubiquitin E3 ligase

@en-gb

Stable X chromosome inactivati ...... LLIN3/SPOP ubiquitin E3 ligase

@nl

prefLabel

Stable X chromosome inactivati ...... LLIN3/SPOP ubiquitin E3 ligase

@ast

Stable X chromosome inactivati ...... LLIN3/SPOP ubiquitin E3 ligase

@en

Stable X chromosome inactivati ...... LLIN3/SPOP ubiquitin E3 ligase

@en-gb

Stable X chromosome inactivati ...... LLIN3/SPOP ubiquitin E3 ligase

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P1433

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PNAS.0408918102

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Stable X chromosome inactivati ...... LLIN3/SPOP ubiquitin E3 ligase

@en

P2093

Anders H Lund

http://www.w3.org/2001/XMLSchema#string

Barbara Panning

http://www.w3.org/2001/XMLSchema#string

Dmitri A Nusinow

http://www.w3.org/2001/XMLSchema#string

Els Verhoeven

http://www.w3.org/2001/XMLSchema#string

Erwin Boutsma

http://www.w3.org/2001/XMLSchema#string

Inhua Muijrers

http://www.w3.org/2001/XMLSchema#string

Inmaculada Hernández-Muñoz

http://www.w3.org/2001/XMLSchema#string

Maarten van Lohuizen

http://www.w3.org/2001/XMLSchema#string

Petra van der Stoop

http://www.w3.org/2001/XMLSchema#string

York Marahrens

http://www.w3.org/2001/XMLSchema#string

P2860

Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells

Histone H2A variants and the inactive X chromosome: identification of a second macroH2A variant

Role of histone H2A ubiquitination in Polycomb silencing

BRCA1 supports XIST RNA concentration on the inactive X chromosome

Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation

Cell cycle-dependent localization of macroH2A in chromatin of the inactive X chromosome

Synergism of Xist RNA, DNA methylation, and histone hypoacetylation in maintaining X chromosome inactivation

Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein

Identification of a novel nuclear speckle-type protein, SPOP

Role of histone H3 lysine 27 methylation in Polycomb-group silencing

P304

7635-7640

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scholarly article

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3440124

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P356

10.1073/PNAS.0408918102

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P433

21

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102

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2005-05-16T00:00:00Z

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7845005

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15897469

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1140410

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