Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development
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arrayMap: a reference resource for genomic copy number imbalances in human malignanciesPLAGL2 regulates Wnt signaling to impede differentiation in neural stem cells and gliomasRecent advances in the molecular understanding of glioblastomaComprehensive genomic characterization defines human glioblastoma genes and core pathwaysEpigenetic setting and reprogramming for neural cell fate determination and differentiationA drosophila model for EGFR-Ras and PI3K-dependent human gliomaPharmacologic inhibition of cyclin-dependent kinases 4 and 6 arrests the growth of glioblastoma multiforme intracranial xenografts.The tyrosine phosphatase PTPRD is a tumor suppressor that is frequently inactivated and mutated in glioblastoma and other human cancersFenton reaction induced cancer in wild type rats recapitulates genomic alterations observed in human cancerThe landscape of somatic copy-number alteration across human cancers.Advances in the genetics of glioblastoma: are we reaching critical mass?A high-throughput computational framework for identifying significant copy number aberrations from array comparative genomic hybridisation data.Exploratory analysis of the copy number alterations in glioblastoma multiforme.A differential wiring analysis of expression data correctly identifies the gene containing the causal mutation.Determining frequent patterns of copy number alterations in cancer.Integrative genome analysis reveals an oncomir/oncogene cluster regulating glioblastoma survivorship.p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation.Making sense of cancer genomic data.Alterations in RD(INK4/ARF) -mediated en bloc regulation of the INK4-ARF locus in human squamous cell carcinoma of the head and neck.Pattern of retinoblastoma pathway inactivation dictates response to CDK4/6 inhibition in GBMIntegrative, multimodal analysis of glioblastoma using TCGA molecular data, pathology images, and clinical outcomes.Identification of valid endogenous control genes for determining gene expression in human glioma.Integration of global spectral karyotyping, CGH arrays, and expression arrays reveals important genes in the pathogenesis of glioblastoma multiforme.Metabolic Effects of Known and Novel HDAC and SIRT Inhibitors in Glioblastomas Independently or Combined with TemozolomideImpact of meriolins, a new class of cyclin-dependent kinase inhibitors, on malignant glioma proliferation and neo-angiogenesis.Somatic p16(INK4a) loss accelerates melanomagenesisAn opposite effect of the CDK inhibitor, p18(INK4c) on embryonic stem cells compared with tumor and adult stem cells.The tumor suppressor CDKN3 controls mitosis.Multi-study integration of brain cancer transcriptomes reveals organ-level molecular signaturesUpregulation of p18Ink4c expression by oncogenic HPV E6 via p53-miR-34a pathway.MicroRNA-27a distinguishes glioblastoma multiforme from diffuse and anaplastic astrocytomas and has prognostic valueBioMiner: Paving the Way for Personalized Medicine.Drosophila melanogaster as a model system for human brain cancers.Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor responseEmerging insights into the molecular and cellular basis of glioblastoma.Studying a complex tumor: potential and pitfalls.Identification of recurrent focal copy number variations and their putative targeted driver genes in ovarian cancerSTAR RNA-binding protein Quaking suppresses cancer via stabilization of specific miRNAProlonged early G(1) arrest by selective CDK4/CDK6 inhibition sensitizes myeloma cells to cytotoxic killing through cell cycle-coupled loss of IRF4.Integrative functional genomics identifies RINT1 as a novel GBM oncogene.
P2860
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P2860
Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development
description
2008 nî lūn-bûn
@nan
2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development
@ast
Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development
@en
Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development
@en-gb
Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development
@nl
type
label
Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development
@ast
Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development
@en
Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development
@en-gb
Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development
@nl
prefLabel
Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development
@ast
Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development
@en
Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development
@en-gb
Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development
@nl
P2093
P2860
P50
P3181
P1433
P1476
Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development
@en
P2093
Alexei Protopopov
Gerald C Chu
Graham Bignell
John Mahoney
Keith L Ligon
Koichi Ichimura
Ruprecht Wiedemeyer
Timothy P Heffernan
V Peter Collins
Webster K Cavenee
P2860
P304
P3181
P356
10.1016/J.CCR.2008.02.010
P407
P577
2008-04-01T00:00:00Z