Control of biochemical reactions through supramolecular RING domain self-assembly.
about
Topors functions as an E3 ubiquitin ligase with specific E2 enzymes and ubiquitinates p53Systematic analysis of dimeric E3-RING interactions reveals increased combinatorial complexity in human ubiquitination networksThe BRCA1/BARD1 heterodimer assembles polyubiquitin chains through an unconventional linkage involving lysine residue K6 of ubiquitinRibavirin as an anti-cancer therapy: acute myeloid leukemia and beyond?The BRCA1 Breast Cancer Suppressor: Regulation of Transport, Dynamics, and Function at Multiple Subcellular LocationsStructural characterization of the Z RING-eIF4E complex reveals a distinct mode of control for eIF4EMass spectrometric and mutational analyses reveal Lys-6-linked polyubiquitin chains catalyzed by BRCA1-BARD1 ubiquitin ligaseStructural organization and Zn2+-dependent subdomain interactions involving autoantigenic epitopes in the Ring-B-box-coiled-coil (RBCC) region of Ro52Recombination-activating gene proteins: more regulation, pleaseBARD1 participates with BRCA1 in homology-directed repair of chromosome breaksPondering the puzzle of PML (promyelocytic leukemia) nuclear bodies: can we fit the pieces together using an RNA regulon?Hexagonal assembly of a restricting TRIM5alpha proteinLabel free fragment screening using surface plasmon resonance as a tool for fragment finding - analyzing parkin, a difficult CNS targetA RING domain gene is expressed in different cell types of leaf trace, stem, and juvenile bundles in the stem vascular system of zinnia.ATM activates p53 by regulating MDM2 oligomerization and E3 processivityRibavirin suppresses eIF4E-mediated oncogenic transformation by physical mimicry of the 7-methyl guanosine mRNA capEukaryotic translation initiation factor 4E activity is modulated by HOXA9 at multiple levels.Protein-protein interactions in dilute to concentrated solutions: α-chymotrypsinogen in acidic conditions.Mutations in the BRCT binding site of BRCA1 result in hyper-recombinationMechanism of p53 stabilization by ATM after DNA damage.Biogenesis of nuclear bodiesPINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial bindingDeconstructing nucleotide binding activity of the Mdm2 RING domain.Composition and assembly of STAT-targeting ubiquitin ligase complexes: paramyxovirus V protein carboxyl terminus is an oligomerization domain.c-Abl phosphorylation of Mdm2 facilitates Mdm2-Mdmx complex formation.MYC in breast tumor progressionMultifunctional nature of the arenavirus RING finger protein Z.Cap-free structure of eIF4E suggests a basis for conformational regulation by its ligands.Role of TRIM5α RING domain E3 ubiquitin ligase activity in capsid disassembly, reverse transcription blockade, and restriction of simian immunodeficiency virus.Contribution of E3-ubiquitin ligase activity to HIV-1 restriction by TRIM5alpha(rh): structure of the RING domain of TRIM5alpha.Identification and characterization of missense alterations in the BRCA1 associated RING domain (BARD1) gene in breast and ovarian cancerThe Mdm2 RING domain C-terminus is required for supramolecular assembly and ubiquitin ligase activity.Further evidence that ribavirin interacts with eIF4ECellular strategies for regulating functional and nonfunctional protein aggregation.The oncogene eIF4E: using biochemical insights to target cancer.Nse1 RING-like domain supports functions of the Smc5-Smc6 holocomplex in genome stability.SUMO5, a Novel Poly-SUMO Isoform, Regulates PML Nuclear Bodies.RING and coiled-coil domains of baculovirus IE2 are critical in strong activation of the cytomegalovirus major immediate-early promoter in mammalian cells.Karyopherin alpha 1 is a putative substrate of the RAG1 ubiquitin ligase.A B-box 2 surface patch important for TRIM5alpha self-association, capsid binding avidity, and retrovirus restriction.
P2860
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P2860
Control of biochemical reactions through supramolecular RING domain self-assembly.
description
2002 nî lūn-bûn
@nan
2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Control of biochemical reactions through supramolecular RING domain self-assembly
@nl
Control of biochemical reactions through supramolecular RING domain self-assembly.
@ast
Control of biochemical reactions through supramolecular RING domain self-assembly.
@en
type
label
Control of biochemical reactions through supramolecular RING domain self-assembly
@nl
Control of biochemical reactions through supramolecular RING domain self-assembly.
@ast
Control of biochemical reactions through supramolecular RING domain self-assembly.
@en
prefLabel
Control of biochemical reactions through supramolecular RING domain self-assembly
@nl
Control of biochemical reactions through supramolecular RING domain self-assembly.
@ast
Control of biochemical reactions through supramolecular RING domain self-assembly.
@en
P2093
P2860
P3181
P356
P1476
Control of biochemical reactions through supramolecular RING domain self-assembly.
@en
P2093
Alex Kentsis
Katherine L B Borden
Ronald E Gordon
P2860
P304
15404-15409
P3181
P356
10.1073/PNAS.202608799
P407
P577
2002-11-18T00:00:00Z