Interaction between cyclin T1 and SCF(SKP2) targets CDK9 for ubiquitination and degradation by the proteasome
about
The gene product Murr1 restricts HIV-1 replication in resting CD4+ lymphocytesAcetylation of conserved lysines in the catalytic core of cyclin-dependent kinase 9 inhibits kinase activity and regulates transcriptionThe human I-mfa domain-containing protein, HIC, interacts with cyclin T1 and modulates P-TEFb-dependent transcriptionThe growth factor granulin interacts with cyclin T1 and modulates P-TEFb-dependent transcriptionLARP7 is a stable component of the 7SK snRNP while P-TEFb, HEXIM1 and hnRNP A1 are reversibly associatedCyclin G2 is degraded through the ubiquitin-proteasome pathway and mediates the antiproliferative effect of activin receptor-like kinase 7Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancerMAQ1 and 7SK RNA interact with CDK9/cyclin T complexes in a transcription-dependent mannerInterplay between cdk9 and NF-kappaB factors determines the level of HIV-1 gene transcription in astrocytic cellsAntiviral activity of CYC202 in HIV-1-infected cellsIdentification and Functional Characterisation of CRK12:CYC9, a Novel Cyclin-Dependent Kinase (CDK)-Cyclin Complex in Trypanosoma bruceiUp-regulation of P-TEFb by the MEK1-extracellular signal-regulated kinase signaling pathway contributes to stimulated transcription elongation of immediate early genes in neuroendocrine cellsDeregulation of F-box proteins and its consequence on cancer development, progression and metastasis.The balance between cell division and endoreplication depends on E2FC-DPB, transcription factors regulated by the ubiquitin-SCFSKP2A pathway in Arabidopsis.SKP2A, an F-box protein that regulates cell division, is degraded via the ubiquitin pathway.BSCTV C2 attenuates the degradation of SAMDC1 to suppress DNA methylation-mediated gene silencing in Arabidopsis.Ubiquitylation of Cdk9 by Skp2 facilitates optimal Tat transactivation.MYC cofactors: molecular switches controlling diverse biological outcomes.Cyclin F is degraded during G2-M by mechanisms fundamentally different from other cyclins.A transcriptional activator is part of an SCF ubiquitin ligase to control degradation of its cofactorsCDK9 is constitutively expressed throughout the cell cycle, and its steady-state expression is independent of SKP2.Oncogenic aberrations of cullin-dependent ubiquitin ligases.Cdt1 degradation to prevent DNA re-replication: conserved and non-conserved pathways.Degradation of p57Kip2 mediated by SCFSkp2-dependent ubiquitylation.Use of ATP analogs to inhibit HIV-1 transcription.Epidermal growth factor promotes cyclin G2 degradation via calpain-mediated proteolysis in gynaecological cancer cells.Microprocessor, Setx, Xrn2, and Rrp6 co-operate to induce premature termination of transcription by RNAPII.Functional interplay between PPM1G and the transcription elongation machinery.The Drosophila F-box protein dSkp2 regulates cell proliferation by targeting Dacapo for degradation.P-TEFb- the final frontier.Arginine methylation increases the stability of human immunodeficiency virus type 1 Tat.CYCLINg through transcription: posttranslational modifications of P-TEFb regulate transcription elongation.HIV-1, ubiquitin and ubiquitin-like proteins: the dialectic interactions of a virus with a sophisticated network of post-translational modifications.Novel roles of Skp2 E3 ligase in cellular senescence, cancer progression, and metastasis.RNA polymerase II elongation control.Lost in transcription: molecular mechanisms that control HIV latencyThe emerging picture of CDK9/P-TEFb: more than 20 years of advances since PITALRE.Assessing the responses of cellular proteins induced by hyaluronic acid-modified surfaces utilizing a mass spectrometry-based profiling system: over-expression of CD36, CD44, CDK9, and PP2A.Transcription factor IIS cooperates with the E3 ligase UBR5 to ubiquitinate the CDK9 subunit of the positive transcription elongation factor B.Targeted ubiquitylation: the prey becomes predator.
P2860
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P2860
Interaction between cyclin T1 and SCF(SKP2) targets CDK9 for ubiquitination and degradation by the proteasome
description
2001 nî lūn-bûn
@nan
2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Interaction between cyclin T1 ...... degradation by the proteasome
@ast
Interaction between cyclin T1 ...... degradation by the proteasome
@en
Interaction between cyclin T1 ...... degradation by the proteasome
@nl
type
label
Interaction between cyclin T1 ...... degradation by the proteasome
@ast
Interaction between cyclin T1 ...... degradation by the proteasome
@en
Interaction between cyclin T1 ...... degradation by the proteasome
@nl
prefLabel
Interaction between cyclin T1 ...... degradation by the proteasome
@ast
Interaction between cyclin T1 ...... degradation by the proteasome
@en
Interaction between cyclin T1 ...... degradation by the proteasome
@nl
P2093
P2860
P1476
Interaction between cyclin T1 ...... degradation by the proteasome
@en
P2093
K Nakayama Ki
K Nakayama
M Benkirane
R E Kiernan
S Emiliani
P2860
P304
P356
10.1128/MCB.21.23.7956-7970.2001
P407
P577
2001-12-01T00:00:00Z