SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box
about
The F-box protein family.The F-box protein Cdc4/Fbxw7 is a novel regulator of neural crest development in Xenopus laevisSignal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCPHuman Cdc34 and Rad6B ubiquitin-conjugating enzymes target repressors of cyclic AMP-induced transcription for proteolysisIdentification of a novel Skp2-like mammalian protein containing F-box and leucine-rich repeatsThe ubiquitin-conjugating enzymes UbcH7 and UbcH8 interact with RING finger/IBR motif-containing domains of HHARI and H7-AP1Stem-loop binding protein, the protein that binds the 3' end of histone mRNA, is cell cycle regulated by both translational and posttranslational mechanismsInsights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complexATF4 degradation relies on a phosphorylation-dependent interaction with the SCF(betaTrCP) ubiquitin ligaseFbx7 functions in the SCF complex regulating Cdk1-cyclin B-phosphorylated hepatoma up-regulated protein (HURP) proteolysis by a proline-rich regionThe F-box protein FBX4 targets PIN2/TRF1 for ubiquitin-mediated degradation and regulates telomere maintenanceThe novel human DNA helicase hFBH1 is an F-box proteinTIP120A associates with cullins and modulates ubiquitin ligase activitySCFbeta-TRCP controls clock-dependent transcription via casein kinase 1-dependent degradation of the mammalian period-1 (Per1) proteinA negatively charged amino acid in Skp2 is required for Skp2-Cks1 interaction and ubiquitination of p27Kip1Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage responseDiversity in tissue expression, substrate binding, and SCF complex formation for a lectin family of ubiquitin ligasesHEC binds to the seventh regulatory subunit of the 26 S proteasome and modulates the proteolysis of mitotic cyclinsCloning and expression analysis of a novel salicylate suppressible gene, Hs-CUL-3, a member of cullin/Cdc53 familyConservation of the centromere/kinetochore protein ZW10FBXO11 promotes the Neddylation of p53 and inhibits its transcriptional activityStructure of a conserved dimerization domain within the F-box protein Fbxo7 and the PI31 proteasome inhibitorHEC, a novel nuclear protein rich in leucine heptad repeats specifically involved in mitosisWD40 protein FBW5 promotes ubiquitination of tumor suppressor TSC2 by DDB1-CUL4-ROC1 ligaseThe Cul3/Klhdc5 E3 ligase regulates p60/katanin and is required for normal mitosis in mammalian cellsUBE2QL1 is disrupted by a constitutional translocation associated with renal tumor predisposition and is a novel candidate renal tumor suppressor geneVHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligasesCyclin F-mediated degradation of ribonucleotide reductase M2 controls genome integrity and DNA repairFbxo45, a novel ubiquitin ligase, regulates synaptic activitySCF(Cyclin F) controls centrosome homeostasis and mitotic fidelity through CP110 degradationA phosphorylated cytoplasmic autoantigen, GW182, associates with a unique population of human mRNAs within novel cytoplasmic specklesRegulation of hypoxia-inducible mRNAs by the von Hippel-Lindau tumor suppressor protein requires binding to complexes containing elongins B/C and Cul2A family of mammalian E3 ubiquitin ligases that contain the UBR box motif and recognize N-degrons.Transcription-dependent nuclear-cytoplasmic trafficking is required for the function of the von Hippel-Lindau tumor suppressor proteinThe Cdc4/34/53 pathway targets Cdc6p for proteolysis in budding yeastAssociation of human CUL-1 and ubiquitin-conjugating enzyme CDC34 with the F-box protein p45(SKP2): evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathwayAn F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-cateninA dual role of cyclin E in cell proliferation and apoptosis may provide a target for cancer therapyThe ETS protein MEF is regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCFSkp2.Interaction between cyclin T1 and SCF(SKP2) targets CDK9 for ubiquitination and degradation by the proteasome
P2860
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P2860
SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box
description
1996 nî lūn-bûn
@nan
1996 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
name
SKP1 connects cell cycle regul ...... rough a novel motif, the F-box
@ast
SKP1 connects cell cycle regul ...... rough a novel motif, the F-box
@en
SKP1 connects cell cycle regul ...... rough a novel motif, the F-box
@nl
type
label
SKP1 connects cell cycle regul ...... rough a novel motif, the F-box
@ast
SKP1 connects cell cycle regul ...... rough a novel motif, the F-box
@en
SKP1 connects cell cycle regul ...... rough a novel motif, the F-box
@nl
prefLabel
SKP1 connects cell cycle regul ...... rough a novel motif, the F-box
@ast
SKP1 connects cell cycle regul ...... rough a novel motif, the F-box
@en
SKP1 connects cell cycle regul ...... rough a novel motif, the F-box
@nl
P2093
P3181
P1433
P1476
SKP1 connects cell cycle regul ...... ough a novel motif, the F-box.
@en
P2093
J W Harper
S J Elledge
P304
P3181
P356
10.1016/S0092-8674(00)80098-7
P407
P577
1996-07-26T00:00:00Z