Structural requirements of ligands for the oxysterol liver X receptors LXRalpha and LXRbeta
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Role of LXRs in control of lipogenesisCharacterization of the human ABCG1 gene: liver X receptor activates an internal promoter that produces a novel transcript encoding an alternative form of the proteinLiver X receptor activation downregulates organic anion transporter 1 (OAT1) in the renal proximal tubuleABCA1 and scavenger receptor class B, type I, are modulators of reverse sterol transport at an in vitro blood-brain barrier constituted of porcine brain capillary endothelial cellsModulation of retinoic acid receptor-related orphan receptor alpha and gamma activity by 7-oxygenated sterol ligandsSynthetic LXR ligand inhibits the development of atherosclerosis in micePolyunsaturated fatty acids decrease the expression of sterol regulatory element-binding protein-1 in CaCo-2 cells: effect on fatty acid synthesis and triacylglycerol transportThe hypocholesterolemic agent LY295427 up-regulates INSIG-1, identifying the INSIG-1 protein as a mediator of cholesterol homeostasis through SREBPLXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytesIdentification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoterRegulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbetaHuman SREBP1c expression in liver is directly regulated by peroxisome proliferator-activated receptor alpha (PPARalpha)PPARgamma1 and LXRalpha face a new regulator of macrophage cholesterol homeostasis and inflammatory responsiveness, AEBP124S-hydroxycholesterol effects on lipid metabolism genes are modeled in traumatic brain injuryControl of cellular cholesterol efflux by the nuclear oxysterol receptor LXR alphaParallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARgammaPractical uses for ecdysteroids in mammals including humans: an updateCurrent trends in oxysterol researchMitochondrial function and regulation of macrophage sterol metabolism and inflammatory responsesRegulation of the cytosolic sulfotransferases by nuclear receptorsFeedback regulation of cholesterol uptake by the LXR-IDOL-LDLR axisIs Western Diet-Induced Nonalcoholic Steatohepatitis in Ldlr-/- Mice Reversible?X-ray crystal structure of the liver X receptor beta ligand binding domain: regulation by a histidine-tryptophan switchThe three-dimensional structure of the liver X receptor beta reveals a flexible ligand-binding pocket that can accommodate fundamentally different ligandsCrystal structure of the heterodimeric complex of LXR and RXR ligand-binding domains in a fully agonistic conformationCytochrome P450s in the synthesis of cholesterol and bile acids--from mouse models to human diseases.Liver X receptors at the intersection of lipid metabolism and atherogenesisMolecular characterization of oxysterol binding to the Epstein-Barr virus-induced gene 2 (GPR183)Enhanced production of 24S-hydroxycholesterol is not sufficient to drive liver X receptor target genes in vivoInactivation of liver X receptor beta leads to adult-onset motor neuron degeneration in male miceThe inhibition of the human cholesterol 7alpha-hydroxylase gene (CYP7A1) promoter by fibrates in cultured cells is mediated via the liver x receptor alpha and peroxisome proliferator-activated receptor alpha heterodimerInterferon-inducible cholesterol-25-hydroxylase broadly inhibits viral entry by production of 25-hydroxycholesterol27-Oxygenation of C27-sterols and 25-hydroxylation of vitamin D3 in kidney: cloning, structure and expression of pig kidney CYP27ASpatial distribution of the pathways of cholesterol homeostasis in human retinaDefective Cytochrome P450-Catalysed Drug Metabolism in Niemann-Pick Type C DiseaseSterol regulatory element-binding protein-2- and liver X receptor-driven dual promoter regulation of hepatic ABC transporter A1 gene expression: mechanism underlying the unique response to cellular cholesterol statusThe effect of 24S-hydroxycholesterol on cholesterol homeostasis in neurons: quantitative changes to the cortical neuron proteomePancreatic exocrine insufficiency in LXRbeta-/- mice is associated with a reduction in aquaporin-1 expression25-Hydroxycholesterol Protects Host against Zika Virus Infection and Its Associated Microcephaly in a Mouse ModelSREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver
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P2860
Structural requirements of ligands for the oxysterol liver X receptors LXRalpha and LXRbeta
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Structural requirements of lig ...... receptors LXRalpha and LXRbeta
@ast
Structural requirements of lig ...... receptors LXRalpha and LXRbeta
@en
Structural requirements of lig ...... receptors LXRalpha and LXRbeta
@nl
type
label
Structural requirements of lig ...... receptors LXRalpha and LXRbeta
@ast
Structural requirements of lig ...... receptors LXRalpha and LXRbeta
@en
Structural requirements of lig ...... receptors LXRalpha and LXRbeta
@nl
prefLabel
Structural requirements of lig ...... receptors LXRalpha and LXRbeta
@ast
Structural requirements of lig ...... receptors LXRalpha and LXRbeta
@en
Structural requirements of lig ...... receptors LXRalpha and LXRbeta
@nl
P2093
P2860
P3181
P356
P1476
Structural requirements of lig ...... receptors LXRalpha and LXRbeta
@en
P2093
B A Janowski
D J Mangelsdorf
G B Wisely
M J Grogan
S A Kliewer
P2860
P304
P3181
P356
10.1073/PNAS.96.1.266
P407
P577
1999-01-05T00:00:00Z