Liddle disease caused by a missense mutation of beta subunit of the epithelial sodium channel gene
about
Role of the UPS in Liddle syndromeThe Nedd4-like protein KIAA0439 is a potential regulator of the epithelial sodium channelThe C2 domain of the ubiquitin protein ligase Nedd4 mediates Ca2+-dependent plasma membrane localizationA mutation causing pseudohypoaldosteronism type 1 identifies a conserved glycine that is involved in the gating of the epithelial sodium channelRegulation of stability and function of the epithelial Na+ channel (ENaC) by ubiquitination.Phosphorylation of Nedd4-2 by Sgk1 regulates epithelial Na(+) channel cell surface expressionThe renal channelopathiesEpithelial Na(+) channel regulation by cytoplasmic and extracellular factorsEpigenetics and the control of the collecting duct epithelial sodium channelAll three WW domains of murine Nedd4 are involved in the regulation of epithelial sodium channels by intracellular Na+The inextricable role of the kidney in hypertensionRaised urinary glucocorticoid and adrenal androgen precursors in the urine of young hypertensive patients: possible evidence for partial glucocorticoid resistanceImmunolocalization of the ubiquitin-protein ligase Nedd4 in tissues expressing the epithelial Na+ channel (ENaC)A human polymorphism affects NEDD4L subcellular targeting by leading to two isoforms that contain or lack a C2 domainThe NH(2) terminus of the epithelial sodium channel contains an endocytic motif.Convergent evolution with combinatorial peptides.Defective regulation of the epithelial Na+ channel by Nedd4 in Liddle's syndrome.Role of epithelial sodium channels and their regulators in hypertension.Ion channel associated diseases: overview of molecular mechanismsOverexpression of the epithelial Na+ channel gamma subunit in collecting duct cells: interactions of Liddle's mutations and steroids on expression and function.Genetic screening of SCNN1B and SCNN1G genes in early-onset hypertensive patients helps to identify Liddle syndrome.Concerted action of ENaC, Nedd4-2, and Sgk1 in transepithelial Na(+) transport.WNK4 regulates activity of the epithelial Na+ channel in vitro and in vivo.ENaCs and ASICs as therapeutic targets.In vivo phosphorylation of the epithelial sodium channel.Developmental programming of hypertension and kidney diseaseParticipation of the ubiquitin-conjugating enzyme UBE2E3 in Nedd4-2-dependent regulation of the epithelial Na+ channel.Redox control of renal function and hypertension.The R563Q mutation of the epithelial sodium channel beta-subunit is associated with hypertension.Epigenetics and the control of epithelial sodium channel expression in collecting duct.Mutations causing Liddle syndrome reduce sodium-dependent downregulation of the epithelial sodium channel in the Xenopus oocyte expression system.TGF-β directs trafficking of the epithelial sodium channel ENaC which has implications for ion and fluid transport in acute lung injury.Beyond genome-wide association studies: new strategies for identifying genetic determinants of hypertension.Liddle syndrome in a Serbian family and literature review of underlying mutations.Blood pressure regulation via the epithelial sodium channel: from gene to kidney and beyond.The long-term complications of the inherited tubulopathies: an adult perspective.The epithelial Na+ channel is inhibited by a peptide derived from proteolytic processing of its alpha subunit.Epithelial Na+ channel mutants causing Liddle's syndrome retain ability to respond to aldosterone and vasopressin.Prevalence of Liddle Syndrome Among Young Hypertension Patients of Undetermined Cause in a Chinese Population.Aldosterone does not require angiotensin II to activate NCC through a WNK4-SPAK-dependent pathway.
P2860
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P2860
Liddle disease caused by a missense mutation of beta subunit of the epithelial sodium channel gene
description
1996 nî lūn-bûn
@nan
1996 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Liddle disease caused by a mis ...... epithelial sodium channel gene
@ast
Liddle disease caused by a mis ...... epithelial sodium channel gene
@en
Liddle disease caused by a mis ...... epithelial sodium channel gene
@nl
type
label
Liddle disease caused by a mis ...... epithelial sodium channel gene
@ast
Liddle disease caused by a mis ...... epithelial sodium channel gene
@en
Liddle disease caused by a mis ...... epithelial sodium channel gene
@nl
prefLabel
Liddle disease caused by a mis ...... epithelial sodium channel gene
@ast
Liddle disease caused by a mis ...... epithelial sodium channel gene
@en
Liddle disease caused by a mis ...... epithelial sodium channel gene
@nl
P2093
P2860
P356
P1476
Liddle disease caused by a mis ...... epithelial sodium channel gene
@en
P2093
P2860
P304
P356
10.1172/JCI118606
P407
P577
1996-04-01T00:00:00Z