Orexin receptors: pharmacology and therapeutic opportunities
about
Physiology of the orexinergic/hypocretinergic system: a revisit in 2012Orexin antagonists for neuropsychiatric disease: progress and potential pitfallsMultiple roles for orexin/hypocretin in addictionFood for thought: the role of appetitive peptides in age-related cognitive declineDifferential effects of a dual orexin receptor antagonist (SB-649868) and zolpidem on sleep initiation and consolidation, SWS, REM sleep, and EEG power spectra in a model of situational insomniaDiscovery of 5''-chloro-N-[(5,6-dimethoxypyridin-2-yl)methyl]-2,2':5',3''-terpyridine-3'-carboxamide (MK-1064): a selective orexin 2 receptor antagonist (2-SORA) for the treatment of insomniaInhibition of Orexin Signaling Promotes Sleep Yet Preserves Salient Arousability in MonkeysDifferential sleep-promoting effects of dual orexin receptor antagonists and GABAA receptor modulatorsThe effects of acute stress-induced sleep disturbance on acoustic trauma-induced tinnitus in rats.The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptorsSubstituted tetrahydroisoquinolines as selective antagonists for the orexin 1 receptor.Neuroprotective Effects of Physical Activity: Evidence from Human and Animal Studies.Integrating modern concepts of insomnia and its contemporary treatment into primary care.Suvorexant for the treatment of insomnia.Suvorexant, a dual orexin receptor antagonist for the management of insomnia.Diaryl urea analogues of SB-334867 as orexin-1 receptor antagonists.Comprehensive RNA-Seq expression analysis of sensory ganglia with a focus on ion channels and GPCRs in Trigeminal gangliaNeural circuit interactions between the dorsal raphe nucleus and the lateral hypothalamus: an experimental and computational study.Effect of 1-substitution on tetrahydroisoquinolines as selective antagonists for the orexin-1 receptorModeling of the OX1R-orexin-A complex suggests two alternative binding modes.The orexin receptor OX(1)R in colon cancer: a promising therapeutic target and a new paradigm in G protein-coupled receptor signalling through ITIMs.Repeated orexin 1 receptor antagonism effects on cocaine seeking in rats.Role of REM Sleep, Melanin Concentrating Hormone and Orexin/Hypocretin Systems in the Sleep Deprivation Pre-Ischemia.Orexin/hypocretin (Orx/Hcrt) transmission and drug-seeking behavior: is the paraventricular nucleus of the thalamus (PVT) part of the drug seeking circuitry?Orexin receptor agonist Yan 7874 is a weak agonist of orexin/hypocretin receptors and shows orexin receptor-independent cytotoxicity.The role of orexins/hypocretins in alcohol use and abuse: an appetitive-reward relationship.Effects of Suvorexant, an Orexin Receptor Antagonist, on Respiration during Sleep In Patients with Obstructive Sleep Apnea.Antagonism of orexin receptors in the posterior hypothalamus reduces hypoglossal and cardiorespiratory excitation from the perifornical hypothalamus.Neuropeptides controlling energy balance: orexins and neuromedins.The hypocretins and the reward function: what have we learned so far?Orexin Receptor Targets for Anti-Relapse Medication Development in Drug Addiction.Control of arousal by the orexin neurons.Dual orexin receptor antagonists show distinct effects on locomotor performance, ethanol interaction and sleep architecture relative to gamma-aminobutyric acid-A receptor modulators.Orexin, orexin receptor antagonists and central cardiovascular control.Postprandial sleep mechanics in Drosophila.Discovery and development of orexin receptor antagonists as therapeutics for insomnia.Orexin A and orexin receptor 1 axonal traffic in dorsal roots at the CNS/PNS interface.Orexin 1 receptor antagonists in compulsive behavior and anxiety: possible therapeutic use.Neural Control of the Upper Airway: Respiratory and State-Dependent Mechanisms.Acute suppressive and long-term phase modulation actions of orexin on the mammalian circadian clock.
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Orexin receptors: pharmacology and therapeutic opportunities
description
2011 nî lūn-bûn
@nan
2011 թուականին հրատարակուած գիտական յօդուած
@hyw
2011 թվականին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Orexin receptors: pharmacology and therapeutic opportunities
@ast
Orexin receptors: pharmacology and therapeutic opportunities
@en
Orexin receptors: pharmacology and therapeutic opportunities
@nl
type
label
Orexin receptors: pharmacology and therapeutic opportunities
@ast
Orexin receptors: pharmacology and therapeutic opportunities
@en
Orexin receptors: pharmacology and therapeutic opportunities
@nl
prefLabel
Orexin receptors: pharmacology and therapeutic opportunities
@ast
Orexin receptors: pharmacology and therapeutic opportunities
@en
Orexin receptors: pharmacology and therapeutic opportunities
@nl
P2860
P1476
Orexin receptors: pharmacology and therapeutic opportunities
@en
P2093
Thomas E Scammell
P2860
P304
P356
10.1146/ANNUREV-PHARMTOX-010510-100528
P407
P577
2011-01-01T00:00:00Z