Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation
about
Mutations in Hedgehog acyltransferase (Hhat) perturb Hedgehog signaling, resulting in severe acrania-holoprosencephaly-agnathia craniofacial defectsRAB23 mutations in Carpenter syndrome imply an unexpected role for hedgehog signaling in cranial-suture development and obesityThe structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signalingHomozygous mutations in IHH cause acrocapitofemoral dysplasia, an autosomal recessive disorder with cone-shaped epiphyses in hands and hips.Connective tissue growth factor coordinates chondrogenesis and angiogenesis during skeletal developmentIndian hedgehog and beta-catenin signaling: role in the sebaceous lineage of normal and neoplastic mammalian epidermisVentral embryonic tissues and Hedgehog proteins induce early AGM hematopoietic stem cell developmentParathyroid hormone receptor type 1/Indian hedgehog expression is preserved in the growth plate of human fetuses affected with fibroblast growth factor receptor type 3 activating mutationsThe Hedgehog-inducible ubiquitin ligase subunit WSB-1 modulates thyroid hormone activation and PTHrP secretion in the developing growth plateHedgehog can drive terminal differentiation of amniote slow skeletal muscleNormal proliferation and differentiation of Hoxc-8 transgenic chondrocytes in vitroThe life cycle of chondrocytes in the developing skeleton.Targeting the Sonic Hedgehog Signaling Pathway: Review of Smoothened and GLI InhibitorsThe Role of Hedgehog Signaling in Tumor Induced Bone DiseaseRoles for Hedgehog signaling in adult organ homeostasis and repairAcquiring chondrocyte phenotype from human mesenchymal stem cells under inflammatory conditionsThe primary cilium as a dual sensor of mechanochemical signals in chondrocytesCilia/Ift protein and motor -related bone diseases and mouse modelsMechanisms and models of endoplasmic reticulum stress in chondrodysplasiaA pathway to bone: signaling molecules and transcription factors involved in chondrocyte development and maturationCurrent insights on the regenerative potential of the periosteum: molecular, cellular, and endogenous engineering approachesLoss of FTO antagonises Wnt signaling and leads to developmental defects associated with ciliopathiesCholesterol metabolism is required for intracellular hedgehog signal transduction in vivoCell Death in Chondrocytes, Osteoblasts, and OsteocytesThe Hedgehog signalling pathway in bone formationRegulation of Long Bone Growth in Vertebrates; It Is Time to Catch UpGenetic background of supernumerary teethArticular Cartilage: Structural and Developmental Intricacies and QuestionsDYNC2LI1 mutations broaden the clinical spectrum of dynein-2 defectsIndian Hedgehog is an antagonist of Wnt signaling in colonic epithelial cell differentiationIdentification of ten loci associated with height highlights new biological pathways in human growthCilia and developmental signalingFilamin B mutations cause chondrocyte defects in skeletal developmentA hypomorphic allele reveals an important role of inturned in mouse skeletal developmentShox2 is required for chondrocyte proliferation and maturation in proximal limb skeletonAn Ift80 mouse model of short rib polydactyly syndromes shows defects in hedgehog signalling without loss or malformation of ciliaHyaluronan production by means of Has2 gene expression in chondrocytes is essential for long bone developmentSynovial joint formation requires local Ext1 expression and heparan sulfate production in developing mouse embryo limbs and spineBMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formationBeta1 integrins regulate chondrocyte rotation, G1 progression, and cytokinesis
P2860
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P2860
Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation
description
1999 nî lūn-bûn
@nan
1999 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Indian hedgehog signaling regu ...... s essential for bone formation
@ast
Indian hedgehog signaling regu ...... s essential for bone formation
@en
Indian hedgehog signaling regu ...... s essential for bone formation
@nl
type
label
Indian hedgehog signaling regu ...... s essential for bone formation
@ast
Indian hedgehog signaling regu ...... s essential for bone formation
@en
Indian hedgehog signaling regu ...... s essential for bone formation
@nl
prefLabel
Indian hedgehog signaling regu ...... s essential for bone formation
@ast
Indian hedgehog signaling regu ...... s essential for bone formation
@en
Indian hedgehog signaling regu ...... s essential for bone formation
@nl
P2093
P2860
P3181
P356
P1433
P1476
Indian hedgehog signaling regu ...... s essential for bone formation
@en
P2093
A P McMahon
B St-Jacques
M Hammerschmidt
P2860
P304
P3181
P356
10.1101/GAD.13.16.2072
P407
P577
1999-08-15T00:00:00Z