Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome
about
Nevoid basal cell carcinoma syndrome (Gorlin syndrome)Histogenesis of retinal dysplasia in trisomy 13The FU gene and its possible protein isoformsCharacterization of two patched receptors for the vertebrate hedgehog protein familyGLI3 mutations in human disorders mimic Drosophila cubitus interruptus protein functions and localizationMammalian suppressor-of-fused modulates nuclear-cytoplasmic shuttling of Gli-1The sonic hedgehog receptor patched associates with caveolin-1 in cholesterol-rich microdomains of the plasma membranePatched1 interacts with cyclin B1 to regulate cell cycle progressionThe TRC8 hereditary kidney cancer gene suppresses growth and functions with VHL in a common pathwaySuppressing Wnt signaling by the hedgehog pathway through sFRP-1Most germ-line mutations in the nevoid basal cell carcinoma syndrome lead to a premature termination of the PATCHED protein, and no genotype-phenotype correlations are evidentTumor suppressor protein VHL inhibits Hedgehog-Gli activation through suppression of Gli1 nuclear localizationActivating Smoothened mutations in sporadic basal-cell carcinomaThe hereditary renal cell carcinoma 3;8 translocation fuses FHIT to a patched-related gene, TRC8Distinct roles of PTCH2 splice variants in Hedgehog signallingThe function and expansion of the Patched- and Hedgehog-related homologs in C. elegansFamilial posterior fossa brain tumors of infancy secondary to germline mutation of the hSNF5 gene.Evidence that the WNT-inducible growth arrest-specific gene 1 encodes an antagonist of sonic hedgehog signaling in the somiteA role of PDGFRalpha in basal cell carcinoma proliferationHedgehog-interacting protein is highly expressed in endothelial cells but down-regulated during angiogenesis and in several human tumorsIndian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formationGenomic screening identifies novel linkages and provides further evidence for a role of MYH9 in nonsyndromic cleft lip and palateIndian hedgehog and beta-catenin signaling: role in the sebaceous lineage of normal and neoplastic mammalian epidermisArsenic trioxide inhibits human cancer cell growth and tumor development in mice by blocking Hedgehog/GLI pathwayCD200-expressing human basal cell carcinoma cells initiate tumor growthArsenic antagonizes the Hedgehog pathway by preventing ciliary accumulation and reducing stability of the Gli2 transcriptional effectorItraconazole and arsenic trioxide inhibit Hedgehog pathway activation and tumor growth associated with acquired resistance to smoothened antagonistsOncogenic bystander radiation effects in Patched heterozygous mouse cerebellumGLI2-specific transcriptional activation of the bone morphogenetic protein/activin antagonist follistatin in human epidermal cellsThe magnitude of hedgehog signaling activity defines skin tumor phenotypeInduction of basal cell carcinomas and trichoepitheliomas in mice overexpressing GLI-1The you gene encodes an EGF-CUB protein essential for Hedgehog signaling in zebrafishA Model for UV-Induction of Skin CancerActivation of the hedgehog pathway in advanced prostate cancerDisruption of Vitamin D and Calcium Signaling in Keratinocytes Predisposes to Skin CancerTargeting the Sonic Hedgehog Signaling Pathway: Review of Smoothened and GLI InhibitorsModeling congenital disease and inborn errors of development in Drosophila melanogasterAdvanced basal cell carcinoma, the hedgehog pathway, and treatment options - role of smoothened inhibitorsTargeting self-renewal pathways in cancer stem cells: clinical implications for cancer therapyVismodegib hedgehog-signaling inhibition and treatment of basal cell carcinomas as well as keratocystic odontogenic tumors in Gorlin syndrome
P2860
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P2860
Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome
description
1996 nî lūn-bûn
@nan
1996 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Mutations of the human homolog ...... basal cell carcinoma syndrome
@ast
Mutations of the human homolog ...... basal cell carcinoma syndrome
@en
Mutations of the human homolog ...... basal cell carcinoma syndrome
@en-gb
Mutations of the human homolog ...... basal cell carcinoma syndrome
@nl
type
label
Mutations of the human homolog ...... basal cell carcinoma syndrome
@ast
Mutations of the human homolog ...... basal cell carcinoma syndrome
@en
Mutations of the human homolog ...... basal cell carcinoma syndrome
@en-gb
Mutations of the human homolog ...... basal cell carcinoma syndrome
@nl
prefLabel
Mutations of the human homolog ...... basal cell carcinoma syndrome
@ast
Mutations of the human homolog ...... basal cell carcinoma syndrome
@en
Mutations of the human homolog ...... basal cell carcinoma syndrome
@en-gb
Mutations of the human homolog ...... basal cell carcinoma syndrome
@nl
P2093
P50
P921
P3181
P1433
P1476
Mutations of the human homolog ...... basal cell carcinoma syndrome
@en
P2093
A Chidambaram
A M Goldstein
B Wainwright
C Pressman
D J Leffell
E Holmberg
P304
P3181
P356
10.1016/S0092-8674(00)81268-4
P407
P577
1996-06-14T00:00:00Z