Analysis of the oligomeric state and transactivation potential of TAp73α.
about
DNA repair and aging: the impact of the p53 familyMechanism of TAp73 inhibition by ΔNp63 and structural basis of p63/p73 hetero-tetramerizationTracing the evolution of the p53 tetramerization domainFunctional interplay between MDM2, p63/p73 and mutant p53∆N-P63α and TA-P63α exhibit intrinsic differences in transactivation specificities that depend on distinct features of DNA target sites.Pathological unfoldomics of uncontrolled chaos: intrinsically disordered proteins and human diseasesWhole-genome cartography of p53 response elements ranked on transactivation potential.TAp73 transcriptionally represses BNIP3 expression.p63 threonine phosphorylation signals the interaction with the WW domain of the E3 ligase Itchp73 regulates basal and starvation-induced liver metabolism in vivo.Quality control in oocytes by p63 is based on a spring-loaded activation mechanism on the molecular and cellular level.How the TP53 family proteins TP63 and TP73 contribute to tumorigenesis: regulators and effectors.Screening for E3-ubiquitin ligase inhibitors: challenges and opportunities.A balancing act: orchestrating amino-truncated and full-length p73 variants as decisive factors in cancer progression.How Does p73 Cause Neuronal Defects?Structural Evolution and Dynamics of the p53 Proteins.p73 - constitutively open for business.Non-oncogenic roles of TAp73: from multiciliogenesis to metabolism.Modulation of p73 isoforms expression induces anti-proliferative and pro-apoptotic activity in mantle cell lymphoma independent of p53 status.Control mechanisms in germ cells mediated by p53 family proteins.Intrinsic aggregation propensity of the p63 and p73 TI domains correlates with p53R175H interaction and suggests further significance of aggregation events in the p53 family.
P2860
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P2860
Analysis of the oligomeric state and transactivation potential of TAp73α.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Analysis of the oligomeric state and transactivation potential of TAp73α.
@en
type
label
Analysis of the oligomeric state and transactivation potential of TAp73α.
@en
prefLabel
Analysis of the oligomeric state and transactivation potential of TAp73α.
@en
P2093
P2860
P50
P356
P1476
Analysis of the oligomeric state and transactivation potential of TAp73α.
@en
P2093
P2860
P2888
P304
P356
10.1038/CDD.2013.23
P577
2013-03-29T00:00:00Z