ARK5 is a tumor invasion-associated factor downstream of Akt signaling
about
A new role of NUAK1: directly phosphorylating p53 and regulating cell proliferationTargeting LKB1 in cancer - exposing and exploiting vulnerabilitiesEvidence of cancer-promoting roles for AMPK and related kinasesCross-talk between JIP3 and JIP1 during glucose deprivation: SEK1-JNK2 and Akt1 act as mediatorsRhoC Promotes Metastasis via Activation of the Pyk2 Pathway in Prostate CancerScreening for microsatellite instability identifies frequent 3'-untranslated region mutation of the RB1-inducible coiled-coil 1 gene in colon tumors.Preclinical pharmacological evaluation of a novel multiple kinase inhibitor, ON123300, in brain tumor modelsCaenorhabditis elegans unc-82 encodes a serine/threonine kinase important for myosin filament organization in muscle during growth.AMPK as a metabolic tumor suppressor: control of metabolism and cell growth.Muscle contractions, AICAR, and insulin cause phosphorylation of an AMPK-related kinase.Regulation of caspase-6 and FLIP by the AMPK family member ARK5.NDR2 acts as the upstream kinase of ARK5 during insulin-like growth factor-1 signaling.Hunk is required for HER2/neu-induced mammary tumorigenesis.MiR-204 inhibits human NSCLC metastasis through suppression of NUAK1.Siomycin A targets brain tumor stem cells partially through a MELK-mediated pathway5'-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments.NUAK2: an emerging acral melanoma oncogeneRewiring of an epithelial differentiation factor, miR-203, to inhibit human squamous cell carcinoma metastasis.Dissociation of Akt1 from its negative regulator JIP1 is mediated through the ASK1-MEK-JNK signal transduction pathway during metabolic oxidative stress: a negative feedback loop.Dual inhibition of CDK4/Rb and PI3K/AKT/mTOR pathways by ON123300 induces synthetic lethality in mantle cell lymphomas.microRNA-203 suppresses invasion and epithelial-mesenchymal transition induction via targeting NUAK1 in head and neck cancer.Potential Role of the AMP-activated Protein Kinase in Regulation of Insulin Action.The Snf1-related kinase, Hunk, is essential for mammary tumor metastasis.NUAK1 (ARK5) Is Associated with Poor Prognosis in Ovarian Cancer.Phosphatidyl inositol-3 kinase (PIK3CA) E545K mutation confers cisplatin resistance and a migratory phenotype in cervical cancer cells.Discovery of 8-cyclopentyl-2-[4-(4-methyl-piperazin-1-yl)-phenylamino]-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carbonitrile (7x) as a potent inhibitor of cyclin-dependent kinase 4 (CDK4) and AMPK-related kinase 5 (ARK5).The LKB1 complex-AMPK pathway: the tree that hides the forestAMPK: a contextual oncogene or tumor suppressor?The multifaceted activities of AMPK in tumor progression--why the "one size fits all" definition does not fit at all?Overexpression of NUAK1 is associated with disease-free survival and overall survival in patients with gastric cancer.Dual Targeting of CDK4 and ARK5 Using a Novel Kinase Inhibitor ON123300 Exerts Potent Anticancer Activity against Multiple Myeloma.Deregulated MYC expression induces dependence upon AMPK-related kinase 5.Next-generation sequencing identifies TGF-β1-associated gene expression profiles in renal epithelial cells reiterated in human diabetic nephropathyARK5 is associated with the invasive and metastatic potential of human breast cancer cells.Epinephrine-induced MMP expression is different between skeletal fibroblasts and myoblasts.Posttranslational regulation of membrane type 1-matrix metalloproteinase (MT1-MMP) in mouse PTEN null prostate cancer cells: Enhanced surface expression and differential O-glycosylation of MT1-MMPMembrane-type 1 matrix metalloproteinase is regulated by sp1 through the differential activation of AKT, JNK, and ERK pathways in human prostate tumor cells.BRSK2 induced by nutrient deprivation promotes Akt activity in pancreatic cancer via downregulation of mTOR activity.NUAK1 links genomic instability and senescence.Adiponectin attenuates profibrotic extracellular matrix remodeling following cardiac injury by up-regulating matrix metalloproteinase 9 expression in mice.
P2860
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P2860
ARK5 is a tumor invasion-associated factor downstream of Akt signaling
description
2004 nî lūn-bûn
@nan
2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
ARK5 is a tumor invasion-associated factor downstream of Akt signaling
@ast
ARK5 is a tumor invasion-associated factor downstream of Akt signaling
@en
ARK5 is a tumor invasion-associated factor downstream of Akt signaling
@nl
type
label
ARK5 is a tumor invasion-associated factor downstream of Akt signaling
@ast
ARK5 is a tumor invasion-associated factor downstream of Akt signaling
@en
ARK5 is a tumor invasion-associated factor downstream of Akt signaling
@nl
prefLabel
ARK5 is a tumor invasion-associated factor downstream of Akt signaling
@ast
ARK5 is a tumor invasion-associated factor downstream of Akt signaling
@en
ARK5 is a tumor invasion-associated factor downstream of Akt signaling
@nl
P2093
P2860
P3181
P1476
ARK5 is a tumor invasion-associated factor downstream of Akt signaling
@en
P2093
Atsuhiro Kishimoto
Atsushi Suzuki
Gen-Ichi Kusakai
Hiroyasu Esumi
Tsutomu Ogura
P2860
P304
P3181
P356
10.1128/MCB.24.8.3526-3535.2004
P407
P577
2004-04-01T00:00:00Z