ARK5 is a tumor invasion-associated factor downstream of Akt signaling - Test2 - elhamkhani - TriplyDB

ARK5 is a tumor invasion-associated factor downstream of Akt signaling

ARK5 is a tumor invasion-associated factor downstream of Akt signaling

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A new role of NUAK1: directly phosphorylating p53 and regulating cell proliferation Targeting LKB1 in cancer - exposing and exploiting vulnerabilities Evidence of cancer-promoting roles for AMPK and related kinases Cross-talk between JIP3 and JIP1 during glucose deprivation: SEK1-JNK2 and Akt1 act as mediators RhoC Promotes Metastasis via Activation of the Pyk2 Pathway in Prostate Cancer Screening for microsatellite instability identifies frequent 3'-untranslated region mutation of the RB1-inducible coiled-coil 1 gene in colon tumors.Preclinical pharmacological evaluation of a novel multiple kinase inhibitor, ON123300, in brain tumor models Caenorhabditis elegans unc-82 encodes a serine/threonine kinase important for myosin filament organization in muscle during growth.AMPK as a metabolic tumor suppressor: control of metabolism and cell growth.Muscle contractions, AICAR, and insulin cause phosphorylation of an AMPK-related kinase.Regulation of caspase-6 and FLIP by the AMPK family member ARK5.NDR2 acts as the upstream kinase of ARK5 during insulin-like growth factor-1 signaling.Hunk is required for HER2/neu-induced mammary tumorigenesis.MiR-204 inhibits human NSCLC metastasis through suppression of NUAK1.Siomycin A targets brain tumor stem cells partially through a MELK-mediated pathway 5'-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments.NUAK2: an emerging acral melanoma oncogene Rewiring of an epithelial differentiation factor, miR-203, to inhibit human squamous cell carcinoma metastasis.Dissociation of Akt1 from its negative regulator JIP1 is mediated through the ASK1-MEK-JNK signal transduction pathway during metabolic oxidative stress: a negative feedback loop.Dual inhibition of CDK4/Rb and PI3K/AKT/mTOR pathways by ON123300 induces synthetic lethality in mantle cell lymphomas.microRNA-203 suppresses invasion and epithelial-mesenchymal transition induction via targeting NUAK1 in head and neck cancer.Potential Role of the AMP-activated Protein Kinase in Regulation of Insulin Action.The Snf1-related kinase, Hunk, is essential for mammary tumor metastasis.NUAK1 (ARK5) Is Associated with Poor Prognosis in Ovarian Cancer.Phosphatidyl inositol-3 kinase (PIK3CA) E545K mutation confers cisplatin resistance and a migratory phenotype in cervical cancer cells.Discovery of 8-cyclopentyl-2-[4-(4-methyl-piperazin-1-yl)-phenylamino]-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carbonitrile (7x) as a potent inhibitor of cyclin-dependent kinase 4 (CDK4) and AMPK-related kinase 5 (ARK5).The LKB1 complex-AMPK pathway: the tree that hides the forest AMPK: a contextual oncogene or tumor suppressor?The multifaceted activities of AMPK in tumor progression--why the "one size fits all" definition does not fit at all?Overexpression of NUAK1 is associated with disease-free survival and overall survival in patients with gastric cancer.Dual Targeting of CDK4 and ARK5 Using a Novel Kinase Inhibitor ON123300 Exerts Potent Anticancer Activity against Multiple Myeloma.Deregulated MYC expression induces dependence upon AMPK-related kinase 5.Next-generation sequencing identifies TGF-β1-associated gene expression profiles in renal epithelial cells reiterated in human diabetic nephropathy ARK5 is associated with the invasive and metastatic potential of human breast cancer cells.Epinephrine-induced MMP expression is different between skeletal fibroblasts and myoblasts.Posttranslational regulation of membrane type 1-matrix metalloproteinase (MT1-MMP) in mouse PTEN null prostate cancer cells: Enhanced surface expression and differential O-glycosylation of MT1-MMP Membrane-type 1 matrix metalloproteinase is regulated by sp1 through the differential activation of AKT, JNK, and ERK pathways in human prostate tumor cells.BRSK2 induced by nutrient deprivation promotes Akt activity in pancreatic cancer via downregulation of mTOR activity.NUAK1 links genomic instability and senescence.Adiponectin attenuates profibrotic extracellular matrix remodeling following cardiac injury by up-regulating matrix metalloproteinase 9 expression in mice.

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ARK5 is a tumor invasion-associated factor downstream of Akt signaling

http://www.wikidata.org/entity/Q24603024

description

2004 nî lūn-bûn

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2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2004 թվականի ապրիլին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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name

ARK5 is a tumor invasion-associated factor downstream of Akt signaling

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ARK5 is a tumor invasion-associated factor downstream of Akt signaling

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ARK5 is a tumor invasion-associated factor downstream of Akt signaling

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type

label

ARK5 is a tumor invasion-associated factor downstream of Akt signaling

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ARK5 is a tumor invasion-associated factor downstream of Akt signaling

@en

ARK5 is a tumor invasion-associated factor downstream of Akt signaling

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prefLabel

ARK5 is a tumor invasion-associated factor downstream of Akt signaling

@ast

ARK5 is a tumor invasion-associated factor downstream of Akt signaling

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ARK5 is a tumor invasion-associated factor downstream of Akt signaling

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MCB.24.8.3526-3535.2004

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Molecular and Cellular Biology

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ARK5 is a tumor invasion-associated factor downstream of Akt signaling

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Atsuhiro Kishimoto

http://www.w3.org/2001/XMLSchema#string

Atsushi Suzuki

http://www.w3.org/2001/XMLSchema#string

Gen-Ichi Kusakai

http://www.w3.org/2001/XMLSchema#string

Hiroyasu Esumi

http://www.w3.org/2001/XMLSchema#string

Jie Lu

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Tsutomu Ogura

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P2860

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

Induction of cell-cell detachment during glucose starvation through F-actin conversion by SNARK, the fourth member of the AMP-activated protein kinase catalytic subunit family

A matrix metalloproteinase expressed on the surface of invasive tumour cells

Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase

The AMP-activated protein kinase--fuel gauge of the mammalian cell?

Mammalian AMP-activated protein kinase subfamily

Identification and characterization of a novel sucrose-non-fermenting protein kinase/AMP-activated protein kinase-related protein kinase, SNARK

Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase

The role of alpha(v)beta(3) in prostate cancer progression

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

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10.1128/MCB.24.8.3526-3535.2004

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8

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15060171

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381626

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