Cyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA-binding activity of E2F-1/DP-1 by phosphorylation
about
EAPP, a novel E2F binding protein that modulates E2F-dependent transcriptionHCF-1 functions as a coactivator for the zinc finger protein Krox20Regulation of TopBP1 oligomerization by Akt/PKB for cell survivalDDB, a putative DNA repair protein, can function as a transcriptional partner of E2F1.Interaction of Sp1 with the growth- and cell cycle-regulated transcription factor E2FRoscovitine, a specific inhibitor of cellular cyclin-dependent kinases, inhibits herpes simplex virus DNA synthesis in the presence of viral early proteinsAssociation of human CUL-1 and ubiquitin-conjugating enzyme CDC34 with the F-box protein p45(SKP2): evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathwayNovel p27(kip1) C-terminal scatter domain mediates Rac-dependent cell migration independent of cell cycle arrest functionsHIRA, the human homologue of yeast Hir1p and Hir2p, is a novel cyclin-cdk2 substrate whose expression blocks S-phase progressionRb and prohibitin target distinct regions of E2F1 for repression and respond to different upstream signalsFunctions of cyclin A1 in the cell cycle and its interactions with transcription factor E2F-1 and the Rb family of proteinsInhibition of E2F-mediated transcription by p202The subcellular localization of E2F-4 is cell-cycle dependentE2F activity is regulated by cell cycle-dependent changes in subcellular localizationInduction of S-phase entry by E2F transcription factors depends on their nuclear localizationSpecific regulation of E2F family members by cyclin-dependent kinasesCyclin A expression is under negative transcriptional control during the cell cycleCell cycle-regulated association of E2F1 and Sp1 is related to their functional interactionIn vivo structure of the human cdc2 promoter: release of a p130-E2F-4 complex from sequences immediately upstream of the transcription initiation site coincides with induction of cdc2 expressionIdentification of E-box factor TFE3 as a functional partner for the E2F3 transcription factorActivation of human B-MYB by cyclinsNetwork calisthenics: control of E2F dynamics in cell cycle entryTo live or let die - complexity within the E2F1 pathwayTruncation and optimisation of peptide inhibitors of cyclin-dependent kinase 2-cyclin a through structure-guided designDrugging the addict: non-oncogene addiction as a target for cancer therapyThe E2F-1 transcription factor is negatively regulated by its interaction with the MDMX proteinA 63-base pair DNA segment containing an Sp1 site but not a canonical E2F site can confer growth-dependent and E2F-mediated transcriptional stimulation of the human ASK gene encoding the regulatory subunit for human Cdc7-related kinaseDifferential activities of E2F family members: unique functions in regulating transcriptionControl of cell cycle transcription during G1 and S phasesCyclin D1 associates with the TBP-associated factor TAF(II)250 to regulate Sp1-mediated transcriptionE2F-3B is a physiological target of cyclin AGenetic ablation of the CDP/Cux protein C terminus results in hair cycle defects and reduced male fertilityRepression by RB1 characterizes genes involved in the penultimate stage of erythroid developmentCyclins and cyclin-dependent kinases: a biochemical viewp130 and p107 use a conserved domain to inhibit cellular cyclin-dependent kinase activityRetinoblastoma protein contains a C-terminal motif that targets it for phosphorylation by cyclin-cdk complexesDNA IR-Double Strand Breaks (DSBs) and cellular response via ATMREPLACE: a strategy for iterative design of cyclin-binding groove inhibitors.A role for the START gene-specific transcription factor complex in the inactivation of cyclin B and Cut2 destructionIdentification of an hexapeptide that binds to a surface pocket in cyclin A and inhibits the catalytic activity of the complex cyclin-dependent kinase 2-cyclin A.
P2860
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P2860
Cyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA-binding activity of E2F-1/DP-1 by phosphorylation
description
1994 nî lūn-bûn
@nan
1994 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Cyclin A/CDK2 binds directly t ...... E2F-1/DP-1 by phosphorylation
@ast
Cyclin A/CDK2 binds directly t ...... E2F-1/DP-1 by phosphorylation
@en
Cyclin A/CDK2 binds directly t ...... E2F-1/DP-1 by phosphorylation
@nl
type
label
Cyclin A/CDK2 binds directly t ...... E2F-1/DP-1 by phosphorylation
@ast
Cyclin A/CDK2 binds directly t ...... E2F-1/DP-1 by phosphorylation
@en
Cyclin A/CDK2 binds directly t ...... E2F-1/DP-1 by phosphorylation
@nl
prefLabel
Cyclin A/CDK2 binds directly t ...... E2F-1/DP-1 by phosphorylation
@ast
Cyclin A/CDK2 binds directly t ...... E2F-1/DP-1 by phosphorylation
@en
Cyclin A/CDK2 binds directly t ...... E2F-1/DP-1 by phosphorylation
@nl
P2093
P2860
P3181
P356
P1476
Cyclin A/CDK2 binds directly t ...... E2F-1/DP-1 by phosphorylation
@en
P2093
P2860
P304
P3181
P356
10.1128/MCB.14.12.8420
P407
P577
1994-12-01T00:00:00Z