Sustained activation of SMAD3/SMAD4 by FOXM1 promotes TGF-β-dependent cancer metastasis - Test2 - elhamkhani - TriplyDB

Sustained activation of SMAD3/SMAD4 by FOXM1 promotes TGF-β-dependent cancer metastasis

Sustained activation of SMAD3/SMAD4 by FOXM1 promotes TGF-β-dependent cancer metastasis

http://www.wikidata.org/entity/Q24613046

about

The Role of Forkhead Box Protein M1 in Breast Cancer Progression and Resistance to Therapy Epithelial-Mesenchymal Transition and Breast Cancer For robust big data analyses: a collection of 150 important pro-metastatic genes Integration of mRNA expression profile, copy number alterations, and microRNA expression levels in breast cancer to improve grade definition.FOXM1 promotes lung adenocarcinoma invasion and metastasis by upregulating SNAIL.Resistance to HER2-targeted therapies: a potential role for FOXM1.Tumour suppressor TRIM33 targets nuclear β-catenin degradation Glioblastoma multiforme formation and EMT: role of FoxM1 transcription factor FOXM1 confers to epithelial-mesenchymal transition, stemness and chemoresistance in epithelial ovarian carcinoma cells.FoxM1 Drives a Feed-Forward STAT3-Activation Signaling Loop That Promotes the Self-Renewal and Tumorigenicity of Glioblastoma Stem-like Cells.A FOXM1 Dependent Mesenchymal-Epithelial Transition in Retinal Pigment Epithelium Cells.FoxM1 promotes breast tumorigenesis by activating PDGF-A and forming a positive feedback loop with the PDGF/AKT signaling pathway.Integrating transcriptional and protein interaction networks to prioritize condition-specific master regulators.Essential roles of FoxM1 in Ras-induced liver cancer progression and in cancer cells with stem cell features.Forkhead Box M1 Is Essential for Nuclear Localization of Glioma-associated Oncogene Homolog 1 in Glioblastoma Multiforme Cells by Promoting Importin-7 Expression.Kaempferol Suppresses Transforming Growth Factor-β1-Induced Epithelial-to-Mesenchymal Transition and Migration of A549 Lung Cancer Cells by Inhibiting Akt1-Mediated Phosphorylation of Smad3 at Threonine-179.Suppression of invasion and metastasis of triple-negative breast cancer lines by pharmacological or genetic inhibition of slug activity.PKM2 regulates neural invasion of and predicts poor prognosis for human hilar cholangiocarcinoma.Merlin/NF2 Suppresses Pancreatic Tumor Growth and Metastasis by Attenuating the FOXM1-Mediated Wnt/β-Catenin Signaling.c-Jun N-terminal kinase inhibitor favors transforming growth factor-β to antagonize hepatitis B virus X protein-induced cell growth promotion in hepatocellular carcinoma The EGF receptor ligand amphiregulin controls cell division via FoxM1 Wnt-induced deubiquitination FoxM1 ensures nucleus β-catenin transactivation.Smad3 Sensitizes Hepatocelluar Carcinoma Cells to Cisplatin by Repressing Phosphorylation of AKT.Association between transforming growth factor-β1 expression and the clinical features of triple negative breast cancer.HGF/Met and FOXM1 form a positive feedback loop and render pancreatic cancer cells resistance to Met inhibition and aggressive phenotypes.miR-182-5p Induced by STAT3 Activation Promotes Glioma Tumorigenesis.Long non-coding RNA H19 regulates FOXM1 expression by competitively binding endogenous miR-342-3p in gallbladder cancer.OTUB1-catalyzed deubiquitination of FOXM1 facilitates tumor progression and predicts a poor prognosis in ovarian cancer.MicroRNA-567 dysregulation contributes to carcinogenesis of breast cancer, targeting tumor cell proliferation, and migration.Aberrant activation of hedgehog signaling promotes cell proliferation via the transcriptional activation of forkhead Box M1 in colorectal cancer cells.A novel FOXM1 isoform, FOXM1D, promotes epithelial-mesenchymal transition and metastasis through ROCKs activation in colorectal cancer.DLX1 acts as a crucial target of FOXM1 to promote ovarian cancer aggressiveness by enhancing TGF-β/SMAD4 signaling.Plk1 Regulates the Repressor Function of FoxM1b by inhibiting its Interaction with the Retinoblastoma Protein RNA-based ovarian cancer research from 'a gene to systems biomedicine' perspective.Oxidative Stress Gene Expression Profile Correlates with Cancer Patient Poor Prognosis: Identification of Crucial Pathways Might Select Novel Therapeutic Approaches.MELK: a potential novel therapeutic target for TNBC and other aggressive malignancies.FoxM1 overexpression promotes cell proliferation and migration and inhibits apoptosis in hypopharyngeal squamous cell carcinoma resulting in poor clinical prognosis.On a FOX hunt: functions of FOX transcriptional regulators in bladder cancer.Repression of TIF1γ by SOX2 promotes TGF-β-induced epithelial-mesenchymal transition in non-small-cell lung cancer.Suppressed expression of LDHB promotes pancreatic cancer progression via inducing glycolytic phenotype.

P2860

Q26768290-EB3FF420-44D2-464A-A2E3-1B5F558AA772 Q26773055-FAFF1DAC-2341-4950-8F3A-1238BBB5D2A9 Q31155755-5F68A56A-AE3F-408E-8567-D036C73E3A65 Q33670486-25B9D7DE-C0B9-4116-B564-6402EE434719 Q34785529-E0795428-46D7-4A57-8937-EBE135AE5504 Q34955355-28F0078E-DC87-4F6B-B623-2CA2B0F51714 Q35043217-D7F049ED-9C03-41B7-B1BE-BEFEB146D71E Q35234273-0B521118-E0B7-4DDF-ADBC-CE253D9B211D Q35273654-86503FF3-D320-41C4-BD32-4164E0E257A0 Q35674906-B8A75E2E-86D7-4D28-8D4A-F4BB8300D888 Q35677149-6F23BC02-8B88-46B8-8730-0A2C25F0145C Q35793788-4719A079-946B-4392-A833-4149A16F3346 Q35843914-A7BB340D-06AB-4638-BE20-06560BE5C7F0 Q35868092-09419FBF-AC12-4CC2-A078-CC76DE7F2ED0 Q35883866-187F328E-93A3-433F-8EBF-D5A1CF9F9C76 Q35990325-A4FC04B3-A17C-4E7F-ADC9-930B68E2D709 Q36018843-93455C55-849E-4D7E-B06B-63439EAE056B Q36292690-CD3FD896-5A54-4626-924B-DB9BBCF4A0D0 Q36296784-EC25AC87-DF5D-46D6-A080-3007750F5781 Q36520310-41C2FED1-87E0-4B17-B328-FE2491C3D4A9 Q36678172-EDC2B810-3095-4067-B63A-4208B2C3C86B Q36712615-855B3A71-4AA5-4E04-87A8-1EA478B0455A Q36847307-997BDC02-101A-41C2-9E78-510208AA79EC Q36954265-607C8E70-9492-4AB0-AED2-E53EE1D591D7 Q37176592-A8217DBF-C978-4E5C-ABF5-CF971CA9F149 Q37276897-68D9A329-4804-455B-89C1-31C6C5C7610A Q37307816-946519A8-5062-4162-8099-B746B3826520 Q37392807-1CE45ECA-BBAB-4013-8DDB-83EBCC06B07E Q37590613-712FFE97-A832-42C1-9BED-9EDB12082FF0 Q37620836-9F0FF66F-2CD1-4690-B342-D56D6B23165B Q37644045-4E64B287-1EF1-4C87-8B5D-CFB3B595E82C Q37697488-1E470EFF-04E8-421C-A48F-C94E45F86E3A Q37741081-C197B4C1-C889-4B99-B862-9A288AD05EA3 Q38432883-83B59933-9F38-46D8-8D48-4A87D54648B8 Q38645501-2709CCF5-3587-4A54-907F-E8EF449E8135 Q38648606-D0E4AC1D-1471-4963-A06F-E3C8C4C322AE Q38693990-32D55815-2563-4CCE-969E-26DF4D15511F Q38789453-41AB22B5-3093-41DE-87CE-B8D1E7ABC81E Q38876622-E31B93E8-7F4C-4C56-AFEB-7E5B14D05534 Q38895387-694EE1E1-5741-4A81-A0F7-B298ABC5E625

P2860

Sustained activation of SMAD3/SMAD4 by FOXM1 promotes TGF-β-dependent cancer metastasis

http://www.wikidata.org/entity/Q24613046

description

2014 nî lūn-bûn

@nan

2014 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2014年の論文

@ja

2014年学术文章

@wuu

2014年学术文章

@zh-cn

2014年学术文章

@zh-hans

2014年学术文章

@zh-my

2014年学术文章

@zh-sg

2014年學術文章

@yue

name

Sustained activation of SMAD3/SMAD4 by FOXM1 promotes TGF-β-dependent cancer metastasis

@ast

Sustained activation of SMAD3/SMAD4 by FOXM1 promotes TGF-β-dependent cancer metastasis

@en

Sustained activation of SMAD3/SMAD4 by FOXM1 promotes TGF-β-dependent cancer metastasis

@nl

type

label

Sustained activation of SMAD3/SMAD4 by FOXM1 promotes TGF-β-dependent cancer metastasis

@ast

Sustained activation of SMAD3/SMAD4 by FOXM1 promotes TGF-β-dependent cancer metastasis

@en

Sustained activation of SMAD3/SMAD4 by FOXM1 promotes TGF-β-dependent cancer metastasis

@nl

prefLabel

Sustained activation of SMAD3/SMAD4 by FOXM1 promotes TGF-β-dependent cancer metastasis

@ast

Sustained activation of SMAD3/SMAD4 by FOXM1 promotes TGF-β-dependent cancer metastasis

@en

Sustained activation of SMAD3/SMAD4 by FOXM1 promotes TGF-β-dependent cancer metastasis

@nl

P1433

Q24613046-C32CFD88-DD59-4ED8-AC8C-A993617560C3

P1476

Q24613046-ED6F9E3E-D6CF-4537-A422-884963B43C7D

P2093

Q24613046-136AAAE9-3E73-4C2C-A0F4-BC60E19EFD63

Q24613046-41CFDB2F-8DEC-422E-A94A-344FBECF2B02

Q24613046-62804794-205D-48A1-91BF-D04958DA236C

Q24613046-9091E086-C680-4B98-8E6C-1BE6463690C4

Q24613046-9354B2E6-992B-4D5C-93B0-042262FFFCBA

Q24613046-A792EE2B-135C-4F63-B6E0-CEEBC3019AD6

Q24613046-ABF0F6A8-3C77-4F59-98FF-EE32B6B51FB9

Q24613046-B79500E2-F945-4800-B3DE-2D32E4B8DDD1

Q24613046-C41DDE64-998C-4BCC-9A4D-4F391A2A92E8

Q24613046-FC8EFC0E-F9FC-4531-9793-72D51A40EB41

P2860

Q24613046-05BE1E0D-A1E5-49E0-B0F5-65C9E497A7F3

Q24613046-0D116868-BF97-4F33-9579-8E9A1BF35C23

Q24613046-185AD898-CEA0-45A0-BCB2-1B3057BECA43

Q24613046-240B4E48-B0D6-4DD3-A549-1557683369FA

Q24613046-2493315A-41CF-4B27-A85F-8F7084648DAC

Q24613046-26991765-A30A-428A-A68A-BEDB88482963

Q24613046-28A4D867-A340-41E4-84C4-E7504FD1B9B1

Q24613046-291642E1-DC63-4E12-9D71-04B49DC6E02E

Q24613046-305F135F-0A59-4073-A7C0-E4356BDD4DA6

Q24613046-386569A1-986A-4A34-B1AB-CF050BD8CAC4

P304

Q24613046-BDC93BA7-CB36-4961-AF99-6B7CF14AE78D

P31

Q24613046-E1AA7DC0-8B6B-449B-A6C3-F33DC3BFAA24

P3181

Q24613046-01486E94-5920-42BE-8320-1DD1C1DB1796

P356

Q24613046-9A65F38F-668A-4305-8F02-C7CC1095E2EF

P407

Q24613046-D63A7A5F-F501-4562-B946-B00F76E41BB7

P433

Q24613046-D743873D-9EFB-4F63-B6E7-9BD9FD2A8086

P478

Q24613046-1C0C86A4-1B0F-49AC-8EDE-9FEA8E36614D

P50

Q24613046-A2887AA5-8414-4DA9-90FD-4833693B964F

P577

Q24613046-0A720217-972E-4A12-B481-C15288B89A40

P698

Q24613046-90E8A184-FC55-484A-8D77-780662EED678

P932

Q24613046-0ECD94A5-5D2A-450B-9649-9F0EDB226108

P3181

P356

P1433

Journal of Clinical Investigation

P1476

Sustained activation of SMAD3/SMAD4 by FOXM1 promotes TGF-β-dependent cancer metastasis

@en

P2093

Guanzhen Yu

http://www.w3.org/2001/XMLSchema#string

Jianfei Xue

http://www.w3.org/2001/XMLSchema#string

Mien-Chie Hung

http://www.w3.org/2001/XMLSchema#string

Mingguang Liu

http://www.w3.org/2001/XMLSchema#string

Raymond Sawaya

http://www.w3.org/2001/XMLSchema#string

Suyun Huang

http://www.w3.org/2001/XMLSchema#string

Wen-Tai Chiu

http://www.w3.org/2001/XMLSchema#string

Xia Lin

http://www.w3.org/2001/XMLSchema#string

Xin-Hua Feng

http://www.w3.org/2001/XMLSchema#string

Yao-Hui Chen

http://www.w3.org/2001/XMLSchema#string

P2860

FoxM1 promotes β-catenin nuclear localization and controls Wnt target-gene expression and glioma tumorigenesis

A systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cells

Nuclear targeting of transforming growth factor-beta-activated Smad complexes

FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination

Nuclear export of Smad2 and Smad3 by RanBP3 facilitates termination of TGF-beta signaling

PPM1A functions as a Smad phosphatase to terminate TGFbeta signaling

FOXM1 confers acquired cisplatin resistance in breast cancer cells

A Poised Chromatin Platform for TGF-β Access to Master Regulators

A Smad transcriptional corepressor

Hematopoiesis controlled by distinct TIF1gamma and Smad4 branches of the TGFbeta pathway

P304

564-79

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

2139612

http://www.w3.org/2001/XMLSchema#string

P356

10.1172/JCI71104

http://www.w3.org/2001/XMLSchema#string

P407

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

124

http://www.w3.org/2001/XMLSchema#string

P50

René H. Medema

P577

2014-02-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

24382352

http://www.w3.org/2001/XMLSchema#string

P932

3904622

http://www.w3.org/2001/XMLSchema#string