Metformin activates AMP kinase through inhibition of AMP deaminase
about
Repurposing metformin: an old drug with new tricks in its binding pocketsCurrent understanding of metformin effect on the control of hyperglycemia in diabetesAMP deaminase 1 gene polymorphism and heart disease-a genetic association that highlights new treatmentMetformin: An Old Drug for the Treatment of Diabetes but a New Drug for the Protection of the EndotheliumAMPK: a target for drugs and natural products with effects on both diabetes and cancerAMPK: An emerging target for modification of injury-induced pain plasticity.Targeting myocardial substrate metabolism in heart failure: potential for new therapiesMetformin and metabolic diseases: a focus on hepatic aspectsActivation of AMPK by the putative dietary restriction mimetic metformin is insufficient to extend lifespan in DrosophilaIn Vitro Anti-Echinococcal and Metabolic Effects of Metformin Involve Activation of AMP-Activated Protein Kinase in Larval Stages of Echinococcus granulosusMedium Renewal Blocks Anti-Proliferative Effects of Metformin in Cultured MDA-MB-231 Breast Cancer CellsAMPK: a nutrient and energy sensor that maintains energy homeostasisAdenosine Monophosphate-activated Protein Kinase (AMPK) Activators For the Prevention, Treatment and Potential Reversal of Pathological Pain.Metformin promotes lifespan through mitohormesis via the peroxiredoxin PRDX-2Uric acid-dependent inhibition of AMP kinase induces hepatic glucose production in diabetes and starvation: evolutionary implications of the uricase loss in hominidsSugar, uric acid, and the etiology of diabetes and obesity.Novel therapeutic strategies for adult obese asthmatics.Colorectal and Prostate Cancer Risk in Diabetes: Metformin, an Actor behind the Scene.Effects of metformin, buformin, and phenformin on the post-initiation stage of chemically induced mammary carcinogenesis in the rat.Counteracting roles of AMP deaminase and AMP kinase in the development of fatty liverActivating AMP-activated protein kinase (AMPK) slows renal cystogenesis.Novel insulin sensitizer modulates nutrient sensing pathways and maintains β-cell phenotype in human islets.AMPD1: a novel therapeutic target for reversing insulin resistance.Metformin induces apoptosis through AMPK-dependent inhibition of UPR signaling in ALL lymphoblasts.Antiproliferative and metabolic effects of metformin in a preoperative window clinical trial for endometrial cancer.Global metabolite profiling of mice with high-fat diet-induced obesity chronically treated with AMPK activators R118 or metformin reveals tissue-selective alterations in metabolic pathwaysOpposing activity changes in AMP deaminase and AMP-activated protein kinase in the hibernating ground squirrelGenome protective effect of metformin as revealed by reduced level of constitutive DNA damage signalingResveratrol engages AMPK to attenuate ERK and mTOR signaling in sensory neurons and inhibits incision-induced acute and chronic pain.Improved Muscle Function in Duchenne Muscular Dystrophy through L-Arginine and Metformin: An Investigator-Initiated, Open-Label, Single-Center, Proof-Of-Concept-Study.Organismal carbohydrate and lipid homeostasis.AMP-Activated Protein Kinase Regulates Oxidative Metabolism in Caenorhabditis elegans through the NHR-49 and MDT-15 Transcriptional RegulatorsDefining the contribution of AMP-activated protein kinase (AMPK) and protein kinase C (PKC) in regulation of glucose uptake by metformin in skeletal muscle cellsMolecular features of biguanides required for targeting of mitochondrial respiratory complex I and activation of AMP-kinase.Metabolomic fingerprint reveals that metformin impairs one-carbon metabolism in a manner similar to the antifolate class of chemotherapy drugs.Metformin in non-diabetic patients presenting with ST elevation myocardial infarction: rationale and design of the glycometabolic intervention as adjunct to primary percutaneous intervention in ST elevation myocardial infarction (GIPS)-III trialAMP kinase activation improves angiogenesis in pulmonary artery endothelial cells with in utero pulmonary hypertension.Metformin inhibits growth of human non-small cell lung cancer cells via liver kinase B-1-independent activation of adenosine monophosphate-activated protein kinase.Mitochondrial biogenesis: a therapeutic target for neurodevelopmental disorders and neurodegenerative diseasesMetformin Protects Against Cisplatin-Induced Tubular Cell Apoptosis and Acute Kidney Injury via AMPKα-regulated Autophagy Induction.
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P2860
Metformin activates AMP kinase through inhibition of AMP deaminase
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Metformin activates AMP kinase through inhibition of AMP deaminase
@ast
Metformin activates AMP kinase through inhibition of AMP deaminase
@en
Metformin activates AMP kinase through inhibition of AMP deaminase
@nl
type
label
Metformin activates AMP kinase through inhibition of AMP deaminase
@ast
Metformin activates AMP kinase through inhibition of AMP deaminase
@en
Metformin activates AMP kinase through inhibition of AMP deaminase
@nl
prefLabel
Metformin activates AMP kinase through inhibition of AMP deaminase
@ast
Metformin activates AMP kinase through inhibition of AMP deaminase
@en
Metformin activates AMP kinase through inhibition of AMP deaminase
@nl
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P1476
Metformin activates AMP kinase through inhibition of AMP deaminase
@en
P2093
Jiangyong Ouyang
Rahulkumar A Parakhia
Raymond S Ochs
P2860
P3181
P356
10.1074/JBC.M110.121806
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P577
2011-01-07T00:00:00Z