Negative feedback control of HIF-1 through REDD1-regulated ROS suppresses tumorigenesis
about
Reactive oxygen species, nutrition, hypoxia and diseases: Problems solved?Multifaceted role of insulin-like growth factors and mammalian target of rapamycin in skeletal muscleIs REDD1 a Metabolic Éminence Grise?Impact of pyrrolidine dithiocarbamate and interleukin-6 on mammalian target of rapamycin complex 1 regulation and global protein translationRTP801/REDD1: a stress coping regulator that turns into a troublemaker in neurodegenerative disordersRTP801/REDD1 regulates the timing of cortical neurogenesis and neuron migrationFeedback control of p53 translation by REDD1 and mTORC1 limits the p53-dependent DNA damage responseThe leukemia-specific fusion gene ETV6/RUNX1 perturbs distinct key biological functions primarily by gene repressionROS function in redox signaling and oxidative stressGlyceollins trigger anti-proliferative effects through estradiol-dependent and independent pathways in breast cancer cellsStress signaling and the shaping of the mammary tissue in development and cancer.Roles of individual prolyl-4-hydroxylase isoforms in the first 24 hours following transient focal cerebral ischaemia: insights from genetically modified mice.Quantitative Lys-ϵ-Gly-Gly (diGly) proteomics coupled with inducible RNAi reveals ubiquitin-mediated proteolysis of DNA damage-inducible transcript 4 (DDIT4) by the E3 ligase HUWE1.Aconitase causes iron toxicity in Drosophila pink1 mutantsIntravenous ascorbic acid to prevent and treat cancer-associated sepsis?Essential role for autophagy during invariant NKT cell development.HIF-1α restricts NF-κB-dependent gene expression to control innate immunity signalsSirT3 suppresses hypoxia inducible factor 1α and tumor growth by inhibiting mitochondrial ROS production.Metformin inhibits growth of human glioblastoma cells and enhances therapeutic responseParkin loss of function contributes to RTP801 elevation and neurodegeneration in Parkinson's disease.The mitochondrial protein C1qbp promotes cell proliferation, migration and resistance to cell death.REDD1 Is Essential for Optimal T Cell Proliferation and Survival.Boswellic acid induces epigenetic alterations by modulating DNA methylation in colorectal cancer cells.Transcriptional regulation of gene expression during osmotic stress responses by the mammalian target of rapamycin.Hypoxia promotes dissemination of multiple myeloma through acquisition of epithelial to mesenchymal transition-like features.Silymarin Suppresses Cellular Inflammation By Inducing Reparative Stress SignalingMetabolic control of the Treg/Th17 axisAge-dependent changes in the protein expression levels of Redd1 and mTOR in the gerbil hippocampus during normal agingHypoxia induces a phase transition within a kinase signaling network in cancer cellsAngiogenesis genes, dietary oxidative balance and breast cancer risk and progression: the Breast Cancer Health Disparities Study.Expression Profile of Long Noncoding RNAs in Peripheral Blood Mononuclear Cells from Multiple Sclerosis PatientsAdaptive and maladaptive cardiorespiratory responses to continuous and intermittent hypoxia mediated by hypoxia-inducible factors 1 and 2.Loss of the tumor suppressor LKB1 promotes metabolic reprogramming of cancer cells via HIF-1α.Methylseleninic acid elevates REDD1 and inhibits prostate cancer cell growth despite AKT activation and mTOR dysregulation in hypoxia.Molecular responses to hypoxia-inducible factor 1α and beyond.Genetic determinants of oxidative stress-mediated sensitization of drug-resistant cancer cells.Transcriptional regulation of the stress response by mTOR.Expression of Tyrosine Hydroxylase is Negatively Regulated Via Prion Protein.The TNF-α/ROS/HIF-1-induced upregulation of FoxMI expression promotes HCC proliferation and resistance to apoptosis.A REDD1/TXNIP pro-oxidant complex regulates ATG4B activity to control stress-induced autophagy and sustain exercise capacity.
P2860
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P2860
Negative feedback control of HIF-1 through REDD1-regulated ROS suppresses tumorigenesis
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Negative feedback control of HIF-1 through REDD1-regulated ROS suppresses tumorigenesis
@ast
Negative feedback control of HIF-1 through REDD1-regulated ROS suppresses tumorigenesis
@en
Negative feedback control of HIF-1 through REDD1-regulated ROS suppresses tumorigenesis
@nl
type
label
Negative feedback control of HIF-1 through REDD1-regulated ROS suppresses tumorigenesis
@ast
Negative feedback control of HIF-1 through REDD1-regulated ROS suppresses tumorigenesis
@en
Negative feedback control of HIF-1 through REDD1-regulated ROS suppresses tumorigenesis
@nl
prefLabel
Negative feedback control of HIF-1 through REDD1-regulated ROS suppresses tumorigenesis
@ast
Negative feedback control of HIF-1 through REDD1-regulated ROS suppresses tumorigenesis
@en
Negative feedback control of HIF-1 through REDD1-regulated ROS suppresses tumorigenesis
@nl
P2093
P2860
P3181
P356
P1476
Negative feedback control of HIF-1 through REDD1-regulated ROS suppresses tumorigenesis
@en
P2093
Andrew R Crawford
Dennis Sgroi
Douangsone D Vadysirisack
Leif W Ellisen
M Phillip DeYoung
Zachary M Nash
P2860
P304
P3181
P356
10.1073/PNAS.0907705107
P407
P50
P577
2010-02-22T00:00:00Z