Metformin inhibits growth of human glioblastoma cells and enhances therapeutic response - Test2 - elhamkhani - TriplyDB

Metformin inhibits growth of human glioblastoma cells and enhances therapeutic response

Metformin inhibits growth of human glioblastoma cells and enhances therapeutic response

http://www.wikidata.org/entity/Q35600122

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Unexploited Antineoplastic Effects of Commercially Available Anti-Diabetic Drugs Therapeutic interactions of autophagy with radiation and temozolomide in glioblastoma: evidence and issues to resolve For glioma, a sweet side to diabetes Phosphatidylcholine-specific phospholipase C inhibition down- regulates CXCR4 expression and interferes with proliferation, invasion and glycolysis in glioma cells.Metformin inhibited esophageal squamous cell carcinoma proliferation in vitro and in vivo and enhanced the anti-cancer effect of cisplatin Metformin and temozolomide act synergistically to inhibit growth of glioma cells and glioma stem cells in vitro and in vivo.Targeting metabolic flexibility by simultaneously inhibiting respiratory complex I and lactate generation retards melanoma progression.Metformin suppresses hypoxia-induced stabilization of HIF-1α through reprogramming of oxygen metabolism in hepatocellular carcinoma.Complete diagnostics and clinical approach for a female patient with unusual glioblastoma: A case study.Metformin inhibits proliferation and migration of glioblastoma cells independently of TGF-β2.Kukoamine A inhibits human glioblastoma cell growth and migration through apoptosis induction and epithelial-mesenchymal transition attenuation.Cripto-1: an extracellular protein - connecting the sequestered biological dots.Repurposing some older drugs that cross the blood-brain barrier and have potential anticancer activity to provide new treatment options for glioblastoma.Metformin suppressed the proliferation of LoVo cells and induced a time-dependent metabolic and transcriptional alteration.A Metabolic Inhibitory Cocktail for Grave Cancers: Metformin, Pioglitazone and Lithium Combination in Treatment of Pancreatic Cancer and Glioblastoma Multiforme.Stattic and metformin inhibit brain tumor initiating cells by reducing STAT3-phosphorylation.Metformin treatment reduces temozolomide resistance of glioblastoma cells.Metabolic Reprogramming in Glioma.Use of an anti-viral drug, Ribavirin, as an anti-glioblastoma therapeutic.Metformin requires 4E-BPs to induce apoptosis and repress translation of Mcl-1 in hepatocellular carcinoma cells.Blocking epithelial-to-mesenchymal transition in glioblastoma with a sextet of repurposed drugs: the EIS regimen.New metformin derivative HL156A prevents oral cancer progression by inhibiting the insulin-like growth factor/AKT/mammalian target of rapamycin pathways.Metformin and temozolomide, a synergic option to overcome resistance in glioblastoma multiforme models.Low Dose of Doxorubicin Potentiates the Effect of Temozolomide in Glioblastoma Cells.Metformin Enhanced in Vitro Radiosensitivity Associates with G2/M Cell Cycle Arrest and Elevated Adenosine-5'-monophosphate-activated Protein Kinase Levels in Glioblastoma.High-Dose Metformin Plus Temozolomide Shows Increased Anti-tumor Effects in Glioblastoma In Vitro and In Vivo Compared with Monotherapy.Metformin inhibits TGF-β1-induced epithelial-to-mesenchymal transition-like process and stem-like properties in GBM via AKT/mTOR/ZEB1 pathway.Drug Repositioning in Glioblastoma: A Pathway Perspective.Unveiling new interdependencies between significant DNA methylation sites, gene expression profiles and glioma patients survival.Ribavirin as a potential therapeutic for atypical teratoid/rhabdoid tumors.Bioenergetic modulators hamper cancer cell viability and enhance response to chemotherapy.Drug Repurposing of Metabolic Agents in Malignant Glioma Combined Modulation of Tumor Metabolism by Metformin and Diclofenac in Glioma

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Metformin inhibits growth of human glioblastoma cells and enhances therapeutic response

http://www.wikidata.org/entity/Q35600122

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2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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2015年论文

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2015年论文

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name

Metformin inhibits growth of human glioblastoma cells and enhances therapeutic response

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Metformin inhibits growth of human glioblastoma cells and enhances therapeutic response

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Metformin inhibits growth of human glioblastoma cells and enhances therapeutic response

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Metformin inhibits growth of human glioblastoma cells and enhances therapeutic response

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Metformin inhibits growth of human glioblastoma cells and enhances therapeutic response

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Metformin inhibits growth of human glioblastoma cells and enhances therapeutic response

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JOURNAL.PONE.0123721

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Metformin inhibits growth of human glioblastoma cells and enhances therapeutic response

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Betty M Tyler

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Christine Toulas

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Estelle Saland

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Henry Brem

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Jean-Emmanuel Sarry

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Julie Sesen

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Nicolas Skuli

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Perrine Dahan

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Sarah J Scotland

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Van-Thi Dang

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P2860

Metformin: An Update

Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase

Regulation of mTOR and cell growth in response to energy stress by REDD1.

Identification of a novel hypoxia-inducible factor 1-responsive gene, RTP801, involved in apoptosis.

Negative feedback control of HIF-1 through REDD1-regulated ROS suppresses tumorigenesis

Hypoxia regulates TSC1/2-mTOR signaling and tumor suppression through REDD1-mediated 14-3-3 shuttling

Investigating metformin for cancer prevention and treatment: the end of the beginning

Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

Feedback control of p53 translation by REDD1 and mTORC1 limits the p53-dependent DNA damage response

Tumor cell metabolism: cancer's Achilles' heel

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e0123721

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scholarly article

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10.1371/JOURNAL.PONE.0123721

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4

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Anthony Lemarié

Elizabeth Cohen-Jonathan Moyal

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2015-04-13T00:00:00Z

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275251966

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