Processive and distributive extension of human telomeres by telomerase under homeostatic and nonequilibrium conditions - Test2 - elhamkhani - TriplyDB

Processive and distributive extension of human telomeres by telomerase under homeostatic and nonequilibrium conditions

Processive and distributive extension of human telomeres by telomerase under homeostatic and nonequilibrium conditions

http://www.wikidata.org/entity/Q24624897

about

Finding the end: recruitment of telomerase to telomeres Genetic and molecular identification of three human TPP1 functions in telomerase action: recruitment, activation, and homeostasis set point regulation Telomerase inhibitor Imetelstat (GRN163L) limits the lifespan of human pancreatic cancer cells Inventory of telomerase components in human cells reveals multiple subpopulations of hTR and hTERT.Contributions of the TEL-patch amino acid cluster on TPP1 to telomeric DNA synthesis by human telomerase.Live Cell Imaging Reveals the Dynamics of Telomerase Recruitment to Telomeres.Telomerase contributes to fludarabine resistance in primary human leukemic lymphocytes.Coordinated DNA dynamics during the human telomerase catalytic cycle.Human cells lacking coilin and Cajal bodies are proficient in telomerase assembly, trafficking and telomere maintenance.Tpz1 controls a telomerase-nonextendible telomeric state and coordinates switching to an extendible state via Ccq1.A role for heterochromatin protein 1γ at human telomeres.Maintaining the end: roles of telomere proteins in end-protection, telomere replication and length regulation Telomeres are partly shielded from ultraviolet-induced damage and proficient for nucleotide excision repair of photoproducts.The Insertion in Fingers Domain in Human Telomerase Can Mediate Enzyme Processivity and Telomerase Recruitment to Telomeres in a TPP1-Dependent Manner.ATR cooperates with CTC1 and STN1 to maintain telomeres and genome integrity in Arabidopsis Roles of telomerase reverse transcriptase N-terminal domain in assembly and activity of Tetrahymena telomerase holoenzyme.Dynamics of Human Telomerase Holoenzyme Assembly and Subunit Exchange across the Cell Cycle.Biogenesis of telomerase ribonucleoproteins Specificity requirements for human telomere protein interaction with telomerase holoenzyme The roles of telomerase in the generation of polyploidy during neoplastic cell growth.Replication of telomeres and the regulation of telomerase.A translocation-defective telomerase with low levels of activity and processivity stabilizes short telomeres and confers immortalization.DNA repair at telomeres: keeping the ends intact.In situ visualization of telomere elongation patterns in human cells.CST for the grand finale of telomere replication.Preferential extension of short telomeres induced by low extracellular pH Telomerase regulation.A role for sister telomere cohesion in telomere elongation by telomerase.Nuclear bodies: multifunctional companions of the genome.Structure-function relationship and biogenesis regulation of the human telomerase holoenzyme.BRG1, the ATPase subunit of SWI/SNF chromatin remodeling complex, interacts with HDAC2 to modulate telomerase expression in human cancer cells.Telomerase Mechanism of Telomere Synthesis.Human telomerase specialization for repeat synthesis by unique handling of primer-template duplex.Centenarians, but not octogenarians, up-regulate the expression of microRNAs DNA-binding determinants and cellular thresholds for human telomerase repeat addition processivity.Dynamic DNA binding, junction recognition and G4 melting activity underlie the telomeric and genome-wide roles of human CST.Telomeres: Implications for Cancer Development.Shwachman-Diamond Syndrome Protein SBDS Maintains Human Telomeres by Regulating Telomerase Recruitment.Kinetics of DNA replication and telomerase reaction at a single-seeded telomere in human cells.Modular ssDNA binding and inhibition of telomerase activity by designer PPR proteins.

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Processive and distributive extension of human telomeres by telomerase under homeostatic and nonequilibrium conditions

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Processive and distributive ex ...... and nonequilibrium conditions

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Processive and distributive ex ...... and nonequilibrium conditions

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Processive and distributive ex ...... and nonequilibrium conditions

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Processive and distributive ex ...... and nonequilibrium conditions

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Processive and distributive ex ...... and nonequilibrium conditions

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Processive and distributive ex ...... and nonequilibrium conditions

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Processive and distributive ex ...... and nonequilibrium conditions

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J.MOLCEL.2011.03.020

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Processive and distributive ex ...... and nonequilibrium conditions

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Eladio Abreu

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Guido Stadler

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Jerry W Shay

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Jinyong Kim

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Michael P Terns

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Rebecca M Terns

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Ugur Eskiocak

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Yong Zhao

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P2860

The POT1-TPP1 telomere complex is a telomerase processivity factor

A human telomerase holoenzyme protein required for Cajal body localization and telomere synthesis

Extension of life-span by introduction of telomerase into normal human cells

Cell cycle-dependent recruitment of telomerase RNA and Cajal bodies to human telomeres

Cell cycle-regulated trafficking of human telomerase to telomeres

TIN2-tethered TPP1 recruits human telomerase to telomeres in vivo

Specific association of human telomerase activity with immortal cells and cancer

Shelterin: the protein complex that shapes and safeguards human telomeres

Protein composition of catalytically active human telomerase from immortal cells

Telomeres shorten during ageing of human fibroblasts

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Woodring E. Wright

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51104745

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