The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset
about
Identification of druggable cancer driver genes amplified across TCGA datasetsImplications of Genetic and Epigenetic Alterations of CDKN2A (p16(INK4a)) in CancerTargeting histone methyltransferases and demethylases in clinical trials for cancer therapyCross-species models of human melanomaOrigins of adult pigmentation: diversity in pigment stem cell lineages and implications for pattern evolutionSerine, glycine and one-carbon units: cancer metabolism in full circleHistone lysine-specific methyltransferases and demethylases in carcinogenesis: new targets for cancer therapy and preventionChromatin signatures of cancerNUAK2 Amplification Coupled with PTEN Deficiency Promotes Melanoma Development via CDK Activation.Epigenetic regulation in human melanoma: past and futureCross-species oncogenomics using zebrafish models of cancerUbiquitination of Lysine 867 of the Human SETDB1 Protein Upregulates Its Histone H3 Lysine 9 (H3K9) Methyltransferase ActivityhnRNP K coordinates transcriptional silencing by SETDB1 in embryonic stem cellsClonal architectures and driver mutations in metastatic melanomasConserved expression signatures between medaka and human pigment cell tumorsLong-term drug administration in the adult zebrafish using oral gavage for cancer preclinical studiesGenome-wide association study identifies a new melanoma susceptibility locus at 1q21.3IDH mutation impairs histone demethylation and results in a block to cell differentiationGenome-wide association study identifies novel loci predisposing to cutaneous melanomaThe mutational landscape of chromatin regulatory factors across 4,623 tumor samples.Optimized cell transplantation using adult rag2 mutant zebrafish.Large-scale quality analysis of published ChIP-seq data.A meta-analysis of multiple matched copy number and transcriptomics data sets for inferring gene regulatory relationships.Oncogenic BRAF disrupts thyroid morphogenesis and function via twist expression.Cancer epigenetics: a brief review.Gene amplification of the histone methyltransferase SETDB1 contributes to human lung tumorigenesis.Histone methyltransferase SETDB1 regulates liver cancer cell growth through methylation of p53An ENU mutagenesis screen identifies novel and known genes involved in epigenetic processes in the mouseEpigenetic regulation of epithelial-mesenchymal transitionZebrafish as a model to assess cancer heterogeneity, progression and relapse.Genetics and epigenetics of the skin meet deep sequence.Transcriptional regulation and its misregulation in disease.Melanoma: clinical features and genomic insights.Genomic profiling by whole-genome single nucleotide polymorphism arrays in Wilms tumor and association with relapse.Abrogation of BRAFV600E-induced senescence by PI3K pathway activation contributes to melanomagenesis.Integrated genomic and gene expression profiling identifies two major genomic circuits in urothelial carcinoma.Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanomaDe novo mutations in histone-modifying genes in congenital heart disease.Transcriptome profiling of CTLs regulated by rapamycin using RNA-SeqZebrafish cancer: the state of the art and the path forward.
P2860
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P2860
The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
The histone methyltransferase ...... noma and accelerates its onset
@ast
The histone methyltransferase ...... noma and accelerates its onset
@en
The histone methyltransferase ...... noma and accelerates its onset
@nl
type
label
The histone methyltransferase ...... noma and accelerates its onset
@ast
The histone methyltransferase ...... noma and accelerates its onset
@en
The histone methyltransferase ...... noma and accelerates its onset
@nl
prefLabel
The histone methyltransferase ...... noma and accelerates its onset
@ast
The histone methyltransferase ...... noma and accelerates its onset
@en
The histone methyltransferase ...... noma and accelerates its onset
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
The histone methyltransferase ...... noma and accelerates its onset
@en
P2093
Audrey Uong
Caitlin Bourque
Christopher J Burke
Craig J Ceol
David A Orlando
Fabrizio Ferré
Judit Jane-Valbuena
Laura A Johnson
Laura Turner
Lauriane Fritsch
P2860
P2888
P3181
P356
10.1038/NATURE09806
P407
P577
2011-03-24T00:00:00Z
P5875
P6179
1037092980