Cytosolic DNA triggers inflammasome activation in keratinocytes in psoriatic lesions - Test2 - elhamkhani - TriplyDB

Cytosolic DNA triggers inflammasome activation in keratinocytes in psoriatic lesions

Cytosolic DNA triggers inflammasome activation in keratinocytes in psoriatic lesions

http://www.wikidata.org/entity/Q24629755

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Recognition of damage-associated molecular patterns related to nucleic acids during inflammation and vaccination GBP5 promotes NLRP3 inflammasome assembly and immunity in mammals Recent advances in understanding psoriasis The role of antimicrobial peptides in chronic inflammatory skin diseases Regulation of inflammasome signaling Intracellular nucleic acid sensors and autoimmunity Inflammasome activation of IL-1 family mediators in response to cutaneous photodamage An Update on PYRIN Domain-Containing Pattern Recognition Receptors: From Immunity to Pathology The new insight into the role of antimicrobial proteins-alarmins in the immunopathogenesis of psoriasis The translocation of nuclear molecules during inflammation and cell death Structure of the Absent in Melanoma 2 (AIM2) Pyrin Domain Provides Insights into the Mechanisms of AIM2 Autoinhibition and Inflammasome Assembly Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor Structural mechanism of DNA recognition by the p202 HINa domain: insights into the inhibition of Aim2-mediated inflammatory signalling The cell biology of inflammasomes: Mechanisms of inflammasome activation and regulation Cathelicidin LL-37: an antimicrobial peptide with a role in inflammatory skin disease Role of the HIN domain in regulation of innate immune responses The nucleic acid-sensing inflammasomes NLRP3 inflammasome activation induced by engineered nanomaterials Interferon-induced guanylate-binding proteins in inflammasome activation and host defense Potential of IL-1, IL-18 and Inflammasome Inhibition for the Treatment of Inflammatory Skin Diseases.Gamma-interferon-inducible lysosomal thiol reductase is upregulated in human melanoma Differential developmental requirement and peripheral regulation for dermal Vγ4 and Vγ6T17 cells in health and inflammation.Molecular mechanisms of liver fibrosis in HIV/HCV coinfection Cathelicidin LL-37: a defense molecule with a potential role in psoriasis pathogenesis.Beyond canonical inflammasomes: emerging pathways in IL-1-mediated autoinflammatory disease Mammalian Argonaute-DNA binding?IL-1β production through the NLRP3 inflammasome by hepatic macrophages links hepatitis C virus infection with liver inflammation and disease Inflammasomes.Deep tissue injury in development of pressure ulcers: a decrease of inflammasome activation and changes in human skin morphology in response to aging and mechanical load.Defining CD4 T cell memory by the epigenetic landscape of CpG DNA methylation AIM2 and NLRC4 inflammasomes contribute with ASC to acute brain injury independently of NLRP3.Regulation of inflammasome activation.The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection.SRSF1 facilitates cytosolic DNA-induced production of type I interferons recognized by RIG-I.Cathelicidin antimicrobial peptide LL-37 in psoriasis enables keratinocyte reactivity against TLR9 ligands.DNA-responsive inflammasomes and their regulators in autoimmunity Critical Role for the DNA Sensor AIM2 in Stem Cell Proliferation and Cancer.U1-small nuclear ribonucleoprotein activates the NLRP3 inflammasome in human monocytes Th17 micro-milieu regulates NLRP1-dependent caspase-5 activity in skin autoinflammation.Multifaceted role of TREX2 in the skin defense against UV-induced skin carcinogenesis.

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P2860

Cytosolic DNA triggers inflammasome activation in keratinocytes in psoriatic lesions

http://www.wikidata.org/entity/Q24629755

description

2011 nî lūn-bûn

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2011 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2011 թվականի մայիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Cytosolic DNA triggers inflammasome activation in keratinocytes in psoriatic lesions

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Cytosolic DNA triggers inflammasome activation in keratinocytes in psoriatic lesions

@en

Cytosolic DNA triggers inflammasome activation in keratinocytes in psoriatic lesions

@nl

type

label

Cytosolic DNA triggers inflammasome activation in keratinocytes in psoriatic lesions

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Cytosolic DNA triggers inflammasome activation in keratinocytes in psoriatic lesions

@en

Cytosolic DNA triggers inflammasome activation in keratinocytes in psoriatic lesions

@nl

prefLabel

Cytosolic DNA triggers inflammasome activation in keratinocytes in psoriatic lesions

@ast

Cytosolic DNA triggers inflammasome activation in keratinocytes in psoriatic lesions

@en

Cytosolic DNA triggers inflammasome activation in keratinocytes in psoriatic lesions

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Science Translational Medicine

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Cytosolic DNA triggers inflammasome activation in keratinocytes in psoriatic lesions

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Christine Göss

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Claudia Kammerbauer

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David Anz

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Jürgen Harder

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Jürgen Schauber

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Maren Simanski

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Regine Gläser

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Robert Besch

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Sarah Koglin

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P2860

Gene from a psoriasis susceptibility locus primes the skin for inflammation

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

Cloning a novel member of the human interferon-inducible gene family associated with control of tumorigenicity in a model of human melanoma

An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist

Generation of pathogenic T(H)17 cells in the absence of TGF-β signalling

Inflammasomes: too big to miss

IL-1 family members and STAT activators induce cytokine production by Th2, Th17, and Th1 cells

Antimicrobial peptides and the skin immune defense system

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82ra38

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2010396

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82

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51117169

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