AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
about
Recognition of damage-associated molecular patterns related to nucleic acids during inflammation and vaccinationSingle nucleotide polymorphisms of human STING can affect innate immune response to cyclic dinucleotidesAPOBEC3 proteins mediate the clearance of foreign DNA from human cellsIFI16 protein mediates the anti-inflammatory actions of the type-I interferons through suppression of activation of caspase-1 by inflammasomesThe NLR adaptor ASC/PYCARD regulates DUSP10, mitogen-activated protein kinase (MAPK), and chemokine induction independent of the inflammasomeIRF7: activation, regulation, modification and functionHMGB1-DNA complex-induced autophagy limits AIM2 inflammasome activation through RAGEIFI16 is an innate immune sensor for intracellular DNACrystal structure of the dimeric coiled-coil domain of the cytosolic nucleic acid sensor LRRFIP1IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infectionActivation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destructionGBP5 promotes NLRP3 inflammasome assembly and immunity in mammalsDAI/ZBP1 recruits RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF-kappaBRIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediateVaccinia virus protein C6 is a virulence factor that binds TBK-1 adaptor proteins and inhibits activation of IRF3 and IRF7Cyclic di-GMP sensing via the innate immune signaling protein STINGHuman cytomegalovirus tegument protein pUL83 inhibits IFI16-mediated DNA sensing for immune evasionIFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIVTRPM2 links oxidative stress to NLRP3 inflammasome activationMany stimuli pull the necrotic trigger, an overviewThe inflammasome: in memory of Dr. Jurg TschoppThe helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cellsInnate immune sensing of DNA virusesRole of the inflammasome, IL-1β, and IL-18 in bacterial infectionsCytosolic DNA triggers inflammasome activation in keratinocytes in psoriatic lesionsInflammasomes: too big to missAicardi-Goutieres syndrome and related phenotypes: linking nucleic acid metabolism with autoimmunityInflammation and its role in age-related macular degenerationConverging roles of caspases in inflammasome activation, cell death and innate immunityInflammasome/IL-1β Responses to Streptococcal PathogensDED or alive: assembly and regulation of the death effector domain complexesCloak and Dagger: Alternative Immune Evasion and Modulation Strategies of PoxvirusesSensors of Infection: Viral Nucleic Acid PRRs in FishInnate Immunity and Biomaterials at the Nexus: Friends or FoesMycobacterium tuberculosis and the host cell inflammasome: a complex relationshipReactive oxygen species at the crossroads of inflammasome and inflammationInterferon-inducible p200-family protein IFI16, an innate immune sensor for cytosolic and nuclear double-stranded DNA: regulation of subcellular localizationDNA vaccines: a simple DNA sensing matter?Molecular mechanisms of inflammasome activation during microbial infectionsIntracellular nucleic acid sensors and autoimmunity
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P2860
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
description
2009 nî lūn-bûn
@nan
2009 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մարտին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
@ast
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
@en
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
@en-gb
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
@nl
type
label
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
@ast
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
@en
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
@en-gb
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
@nl
prefLabel
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
@ast
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
@en
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
@en-gb
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
@nl
P2093
P2860
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P3181
P356
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P1476
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
@en
P2093
Emad S Alnemri
Jianghong Wu
Pinaki Datta
Teresa Fernandes-Alnemri
P2860
P2888
P304
P3181
P356
10.1038/NATURE07710
P407
P50
P577
2009-01-21T00:00:00Z
P5875
P6179
1000921496