Coordination of adjacent domains mediates TACC3-ch-TOG-clathrin assembly and mitotic spindle binding
about
MAPping the Ndc80 loop in cancer: A possible link between Ndc80/Hec1 overproduction and cancer formationAurora-A-Dependent Control of TACC3 Influences the Rate of Mitotic Spindle AssemblyTACC3-ch-TOG track the growing tips of microtubules independently of clathrin and Aurora-A phosphorylationCytoskeleton-associated protein 5 and clathrin heavy chain binding regulates spindle assembly in mouse oocytes.Csi1p recruits alp7p/TACC to the spindle pole bodies for bipolar spindle formation.XTACC3-XMAP215 association reveals an asymmetric interaction promoting microtubule elongation.Cancer cell death induced by novel small molecules degrading the TACC3 protein via the ubiquitin-proteasome pathway.Hsp72 is targeted to the mitotic spindle by Nek6 to promote K-fiber assembly and mitotic progression.The mesh is a network of microtubule connectors that stabilizes individual kinetochore fibers of the mitotic spindle.Upregulation of colonic and hepatic tumor overexpressed gene is significantly associated with the unfavorable prognosis marker of human hepatocellular carcinoma.GTSE1 tunes microtubule stability for chromosome alignment and segregation by inhibiting the microtubule depolymerase MCAK.Linked in: formation and regulation of microtubule attachments during chromosome segregation.Mitotic spindle multipolarity without centrosome amplification.The Clathrin-dependent Spindle Proteome.The Elephant in the Room: The Role of Microtubules in Cancer.The role of TACC3 in mitotic spindle organization.Non-specificity of Pitstop 2 in clathrin-mediated endocytosis.A systems medicine approach for finding target proteins affecting treatment outcomes in patients with non-Hodgkin lymphoma.FGFR3-TACC3 cancer gene fusions cause mitotic defects by removal of endogenous TACC3 from the mitotic spindleTACC3 protein regulates microtubule nucleation by affecting γ-tubulin ring complexes.The centrosomal adaptor TACC3 and the microtubule polymerase chTOG interact via defined C-terminal subdomains in an Aurora-A kinase-independent manner.Systematic Identification of Oncogenic EGFR Interaction PartnersTargeting Alp7/TACC to the spindle pole body is essential for mitotic spindle assembly in fission yeast.A new role for Rab GTPases during early mitotic stages.Mitotic Regulation by NEK Kinase Networks.New tools for "hot-wiring" clathrin-mediated endocytosis with temporal and spatial precision.XMAP215 is a microtubule nucleation factor that functions synergistically with the γ-tubulin ring complex.Mitotic spindle association of TACC3 requires Aurora-A-dependent stabilization of a cryptic α-helix.Solution NMR assignment of the cryptic sixth TOG domain of mini spindles.Oncogenic driver FGFR3-TACC3 is dependent on membrane trafficking and ERK signalingMitotic phosphorylation regulates Hsp72 spindle localization by uncoupling ATP binding from substrate release
P2860
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P2860
Coordination of adjacent domains mediates TACC3-ch-TOG-clathrin assembly and mitotic spindle binding
description
2013 nî lūn-bûn
@nan
2013 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Coordination of adjacent domai ...... ly and mitotic spindle binding
@ast
Coordination of adjacent domai ...... ly and mitotic spindle binding
@en
Coordination of adjacent domai ...... ly and mitotic spindle binding
@en-gb
Coordination of adjacent domai ...... ly and mitotic spindle binding
@nl
type
label
Coordination of adjacent domai ...... ly and mitotic spindle binding
@ast
Coordination of adjacent domai ...... ly and mitotic spindle binding
@en
Coordination of adjacent domai ...... ly and mitotic spindle binding
@en-gb
Coordination of adjacent domai ...... ly and mitotic spindle binding
@nl
prefLabel
Coordination of adjacent domai ...... ly and mitotic spindle binding
@ast
Coordination of adjacent domai ...... ly and mitotic spindle binding
@en
Coordination of adjacent domai ...... ly and mitotic spindle binding
@en-gb
Coordination of adjacent domai ...... ly and mitotic spindle binding
@nl
P2093
P2860
P50
P356
P1476
Coordination of adjacent domai ...... ly and mitotic spindle binding
@en
P2093
Daniel Roth
Fiona E Hood
Samantha J Williams
P2860
P304
P356
10.1083/JCB.201211127
P407
P577
2013-08-05T00:00:00Z