Genomic-scale prioritization of drug targets: the TDR Targets database - Test2 - elhamkhani - TriplyDB

Genomic-scale prioritization of drug targets: the TDR Targets database

Genomic-scale prioritization of drug targets: the TDR Targets database

http://www.wikidata.org/entity/Q24635333

about

Identification of attractive drug targets in neglected-disease pathogens using an in silico approach Drug target prediction and prioritization: using orthology to predict essentiality in parasite genomes A review of the global burden, novel diagnostics, therapeutics, and vaccine targets for cryptosporidium.Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive review Crystal structures of Mycobacterium tuberculosis HspAT and ArAT reveal structural basis of their distinct substrate specificities.RNA interference in Schistosoma mansoni schistosomula: selectivity, sensitivity and operation for larger-scale screening Targeting protein-protein interactions for parasite control Biochemical and structural characterization of CYP124: A methyl-branched lipid -hydroxylase from Mycobacterium tuberculosis The Crystal Structure and Activity of a Putative Trypanosomal Nucleoside Phosphorylase Reveal It to be a Homodimeric Uridine Phosphorylase Assay strategies for the discovery and validation of therapeutics targeting Brugia pahangi Hsp90 A kernel for open source drug discovery in tropical diseases Advancing drug innovation for neglected diseases-criteria for lead progression The Mycobacterium tuberculosis drugome and its polypharmacological implications Integrated dataset of screening hits against multiple neglected disease pathogens HelmCoP: an online resource for helminth functional genomics and drug and vaccine targets prioritization Comparative genomics analysis of Mycobacterium ulcerans for the identification of putative essential genes and therapeutic candidates Exoproteome and secretome derived broad spectrum novel drug and vaccine candidates in Vibrio cholerae targeted by Piper betel derived compounds Kinetic mechanism determination and analysis of metal requirement of dehydroquinate synthase from Mycobacterium tuberculosis H37Rv: an essential step in the function-based rational design of anti-TB drugs The open access malaria box: a drug discovery catalyst for neglected diseases Prediction of the P. falciparum target space relevant to malaria drug discovery In silico repositioning-chemogenomics strategy identifies new drugs with potential activity against multiple life stages of Schistosoma mansoni Application of RNAi to Genomic Drug Target Validation in Schistosomes To Hit or Not to Hit, That Is the Question - Genome-wide Structure-Based Druggability Predictions for Pseudomonas aeruginosa Proteins A Novel Trypanosoma cruzi Protein Associated to the Flagellar Pocket of Replicative Stages and Involved in Parasite Growth Distinctive Behaviors of Druggable Proteins in Cellular Networks A Multilayer Network Approach for Guiding Drug Repositioning in Neglected Diseases The drug target genes show higher evolutionary conservation than non-target genes DEG 10, an update of the database of essential genes that includes both protein-coding genes and noncoding genomic elements Structural Characterization and Ligand/Inhibitor Identification Provide Functional Insights into the Mycobacterium tuberculosis Cytochrome P450 CYP126A1 TiPs: a database of therapeutic targets in pathogens and associated tools ModBase, a database of annotated comparative protein structure models and associated resources.TuberQ: a Mycobacterium tuberculosis protein druggability database Natural products as starting points for future anti-malarial therapies: going back to our roots?Rapid analysis of pharmacology for infectious diseases Drug discovery and the use of computational approaches for infectious diseases.Strategic protein target analysis for developing drugs to stop dental caries.Metabolic network analysis predicts efficacy of FDA-approved drugs targeting the causative agent of a neglected tropical disease LeishCyc: a biochemical pathways database for Leishmania major.Computational prediction of essential genes in an unculturable endosymbiotic bacterium, Wolbachia of Brugia malayi ChEMBL. An interview with John Overington, team leader, chemogenomics at the European Bioinformatics Institute Outstation of the European Molecular Biology Laboratory (EMBL-EBI). Interview by Wendy A. Warr

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Genomic-scale prioritization of drug targets: the TDR Targets database

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description

2008 nî lūn-bûn

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2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2008 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Genomic-scale prioritization of drug targets: the TDR Targets database

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Genomic-scale prioritization of drug targets: the TDR Targets database

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Genomic-scale prioritization of drug targets: the TDR Targets database

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Genomic-scale prioritization of drug targets: the TDR Targets database

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Genomic-scale prioritization of drug targets: the TDR Targets database

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Genomic-scale prioritization of drug targets: the TDR Targets database

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Genomic-scale prioritization of drug targets: the TDR Targets database

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Genomic-scale prioritization of drug targets: the TDR Targets database

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Genomic-scale prioritization of drug targets: the TDR Targets database

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Nature Reviews Drug Discovery

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Genomic-scale prioritization of drug targets: the TDR Targets database

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A W Edith Chan

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Aaron Riechers

http://www.w3.org/2001/XMLSchema#string

Christophe L M J Verlinde

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Dhanasekaran Shanmugam

http://www.w3.org/2001/XMLSchema#string

Feng Chen

http://www.w3.org/2001/XMLSchema#string

Frederick S Buckner

http://www.w3.org/2001/XMLSchema#string

Gaia V Paolini

http://www.w3.org/2001/XMLSchema#string

Gregg McAllister

http://www.w3.org/2001/XMLSchema#string

Ian M Carruthers

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Maria A Doyle

http://www.w3.org/2001/XMLSchema#string

P2860

Experimental Determination and System Level Analysis of Essential Genes in Escherichia coli MG1655

Draft genome of the filarial nematode parasite Brugia malayi

OrthoMCL-DB: querying a comprehensive multi-species collection of ortholog groups.

Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis

Systematic functional analysis of the Caenorhabditis elegans genome using RNAi

OrthoMCL: Identification of Ortholog Groups for Eukaryotic Genomes

Genes required for mycobacterial growth defined by high density mutagenesis

How many drug targets are there?

Prioritizing genomic drug targets in pathogens: application to Mycobacterium tuberculosis

Mining predicted essential genes of Brugia malayi for nematode drug targets

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900-7

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scholarly article

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2130474

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10.1038/NRD2684

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P433

11

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7

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Matthew Berriman

Christiane Hertz-Fowler

Wesley C Van Voorhis

John P. Overington

Gregory J. Crowther

Santiago J. Carmona

Bissan Al-Lazikani

P577

2008-11-01T00:00:00Z

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23389249

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1023310534

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18927591

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3184002

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