RNA interference in Schistosoma mansoni schistosomula: selectivity, sensitivity and operation for larger-scale screening
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An atlas for Schistosoma mansoni organs and life-cycle stages using cell type-specific markers and confocal microscopySchistosomiasis as a disease of stem cellsGenetic manipulation of schistosomes--progress with integration competent vectorsRecent advances in Schistosoma genomicsStructural Basis for Inhibition of Cathepsin B Drug Target from the Human Blood Fluke, Schistosoma mansoniProteomic analysis of human skin treated with larval schistosome peptidases reveals distinct invasion strategies among species of blood flukesIdentification and characterization of a Mef2 transcriptional activator in schistosome parasitesGermline transgenesis and insertional mutagenesis in Schistosoma mansoni mediated by murine leukemia virusPolyethyleneimine mediated DNA transfection in schistosome parasites and regulation of the WNT signaling pathway by a dominant-negative SmMef2Chemical and genetic validation of the statin drug target to treat the helminth disease, schistosomiasisRegulation of Schistosoma mansoni development and reproduction by the mitogen-activated protein kinase signaling pathwayApplication of RNAi to Genomic Drug Target Validation in SchistosomesProlyl Oligopeptidase from the Blood Fluke Schistosoma mansoni: From Functional Analysis to Anti-schistosomal InhibitorsThe Schistosoma mansoni Cytochrome P450 (CYP3050A1) Is Essential for Worm Survival and Egg DevelopmentStructure-Bioactivity Relationship for Benzimidazole Thiophene Inhibitors of Polo-Like Kinase 1 (PLK1), a Potential Drug Target in Schistosoma mansoniNew frontiers in schistosoma genomics and transcriptomicsRapid induction of IgE responses to a worm cysteine protease during murine pre-patent schistosome infectionSchistosome I/Lamides--a new family of bioactive helminth neuropeptides.Suppression of VAMP2 Alters Morphology of the Tegument and Affects Glucose uptake, Development and Reproduction of Schistosoma japonicumExploring the function of protein kinases in schistosomes: perspectives from the laboratory and from comparative genomics.The repertoire of G protein-coupled receptors in the human parasite Schistosoma mansoni and the model organism Schmidtea mediterraneaEpigenetic control of gene function in schistosomes: a source of therapeutic targets?RNAi dynamics in Juvenile Fasciola spp. Liver flukes reveals the persistence of gene silencing in vitro.Schistosoma mansoni U6 gene promoter-driven short hairpin RNA induces RNA interference in human fibrosarcoma cells and schistosomules.Trypsin- and Chymotrypsin-like serine proteases in schistosoma mansoni-- 'the undiscovered country'.Synthesis of a sugar-based thiosemicarbazone series and structure-activity relationship versus the parasite cysteine proteases rhodesain, cruzain, and Schistosoma mansoni cathepsin B1.Schistosoma comparative genomics: integrating genome structure, parasite biology and anthelmintic discovery.Intake of Erythrocytes Required for Reproductive Development of Female Schistosoma japonicum.Transfection of Platyhelminthes.Human U6 promoter drives stronger shRNA activity than its schistosome orthologue in Schistosoma mansoni and human fibrosarcoma cells.High-throughput screening against thioredoxin glutathione reductase identifies novel inhibitors with potential therapeutic value for schistosomiasisA blood fluke serine protease inhibitor regulates an endogenous larval elastase.HIV-1 Integrates Widely throughout the Genome of the Human Blood Fluke Schistosoma mansoni.Schistosome infectivity in the snail, Biomphalaria glabrata, is partially dependent on the expression of Grctm6, a Guadeloupe Resistance Complex proteinSchistosoma mansoni hemozoin modulates alternative activation of macrophages via specific suppression of Retnla expression and secretion.Excretion/secretion products from Schistosoma mansoni adults, eggs and schistosomula have unique peptidase specificity profiles.Adult somatic stem cells in the human parasite Schistosoma mansoniIn vitro cercariae transformation: comparison of mechanical and nonmechanical methods and observation of morphological changes of detached cercariae tailsRNA interference targeting cathepsin B of the carcinogenic liver fluke, Opisthorchis viverrini.New approaches for understanding mechanisms of drug resistance in schistosomes
P2860
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P2860
RNA interference in Schistosoma mansoni schistosomula: selectivity, sensitivity and operation for larger-scale screening
description
2010 nî lūn-bûn
@nan
2010 թուականին հրատարակուած գիտական յօդուած
@hyw
2010 թվականին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
RNA interference in Schistosom ...... ion for larger-scale screening
@ast
RNA interference in Schistosom ...... ion for larger-scale screening
@en
RNA interference in Schistosom ...... ion for larger-scale screening
@nl
type
label
RNA interference in Schistosom ...... ion for larger-scale screening
@ast
RNA interference in Schistosom ...... ion for larger-scale screening
@en
RNA interference in Schistosom ...... ion for larger-scale screening
@nl
prefLabel
RNA interference in Schistosom ...... ion for larger-scale screening
@ast
RNA interference in Schistosom ...... ion for larger-scale screening
@en
RNA interference in Schistosom ...... ion for larger-scale screening
@nl
P2093
P2860
P50
P3181
P1476
RNA interference in Schistosom ...... ion for larger-scale screening
@en
P2093
Brian Suzuki
Conor R Caffrey
Daniel Sojka
Debbie S Ruelas
Jan Dvořák
Kee-Chong Lim
Simon Braschi
Stephanie D Hopkins
P2860
P3181
P356
10.1371/JOURNAL.PNTD.0000850
P407
P5008
P577
2010-10-19T00:00:00Z