SUMOylation target sites at the C terminus protect Axin from ubiquitination and confer protein stability
about
The ubiquitin-specific protease USP34 regulates axin stability and Wnt/β-catenin signalingMethylation by protein arginine methyltransferase 1 increases stability of Axin, a negative regulator of Wnt signalingWnt/beta-catenin signaling and small molecule inhibitorsThe ubiquitin proteasome system in neuropathologyBoth the RGS domain and the six C-terminal amino acids of mouse Axin are required for normal embryogenesisSUMO1-dependent modulation of SERCA2a in heart failure.Discovering implicit entity relation with the gene-citation-gene networkControlled sumoylation of the mevalonate pathway enzyme HMGS-1 regulates metabolism during aging.The protein stability of Axin, a negative regulator of Wnt signaling, is regulated by Smad ubiquitination regulatory factor 2 (Smurf2)SUMO-SIM interactions regulate the activity of RGSZ2 proteins.Axin1 prevents Salmonella invasiveness and inflammatory response in intestinal epithelial cellsModification of nonstructural protein 1 of influenza A virus by SUMO1.A Comprehensive Overview of Skeletal Phenotypes Associated with Alterations in Wnt/β-catenin Signaling in Humans and Mice.Identification and characterization of a small-molecule inhibitor of Wnt signaling in glioblastoma cells.New insights into the regulation of Axin function in canonical Wnt signaling pathway.The way Wnt works: components and mechanism.Regulation of Wnt/β-catenin signaling by posttranslational modificationsRegulating the response to targeted MEK inhibition in melanoma: enhancing apoptosis in NRAS- and BRAF-mutant melanoma cells with Wnt/β-catenin activation.Ubiquitin-dependent and independent roles of SUMO in proteostasis.Targeting c-Met in melanoma: mechanism of resistance and efficacy of novel combinatorial inhibitor therapy.Gtpbp2 is a positive regulator of Wnt signaling and maintains low levels of the Wnt negative regulator Axin.Axin phosphorylation in both Wnt-off and Wnt-on states requires the tumor suppressor APC.APC is K63-polyubiquitinated
P2860
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P2860
SUMOylation target sites at the C terminus protect Axin from ubiquitination and confer protein stability
description
2008 nî lūn-bûn
@nan
2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
SUMOylation target sites at th ...... n and confer protein stability
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SUMOylation target sites at th ...... n and confer protein stability
@en
SUMOylation target sites at th ...... n and confer protein stability
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type
label
SUMOylation target sites at th ...... n and confer protein stability
@ast
SUMOylation target sites at th ...... n and confer protein stability
@en
SUMOylation target sites at th ...... n and confer protein stability
@nl
prefLabel
SUMOylation target sites at th ...... n and confer protein stability
@ast
SUMOylation target sites at th ...... n and confer protein stability
@en
SUMOylation target sites at th ...... n and confer protein stability
@nl
P2093
P2860
P921
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SUMOylation target sites at th ...... n and confer protein stability
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P2093
Frank Costantini
Ian V Chia
Min Jung Kim
P2860
P304
P3181
P356
10.1096/FJ.08-113910
P407
P577
2008-11-01T00:00:00Z