Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway
about
The Frizzled family: receptors for multiple signal transduction pathwaysDisulfide bond assignments of secreted Frizzled-related protein-1 provide insights about Frizzled homology and netrin modulesSecond cysteine-rich domain of Dickkopf-2 activates canonical Wnt signaling pathway via LRP-6 independently of dishevelledAmer1/WTX couples Wnt-induced formation of PtdIns(4,5)P2 to LRP6 phosphorylationR-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6PR72, a novel regulator of Wnt signaling required for Naked cuticle functionActivation of AXIN2 expression by beta-catenin-T cell factor. A feedback repressor pathway regulating Wnt signalingThe ubiquitin-specific protease USP34 regulates axin stability and Wnt/β-catenin signalingThe role of microtubule actin cross-linking factor 1 (MACF1) in the Wnt signaling pathway.Requirement of prorenin receptor and vacuolar H+-ATPase-mediated acidification for Wnt signalingA form of the metabolic syndrome associated with mutations in DYRK1BProtein phosphatase 1 regulates assembly and function of the beta-catenin degradation complexThe low density lipoprotein receptor-related protein 6 interacts with glycogen synthase kinase 3 and attenuates activityStructural and functional characterization of the Wnt inhibitor APC membrane recruitment 1 (Amer1)LDL receptor-related protein LRP6 regulates proliferation and survival through the Wnt cascade in vascular smooth muscle cellsAn LRP5 receptor with internal deletion in hyperparathyroid tumors with implications for deregulated WNT/beta-catenin signalingAutosomal recessive familial exudative vitreoretinopathy is associated with mutations in LRP5.Modulation of LRP6-mediated Wnt signaling by molecular chaperone MesdI-mfa domain proteins interact with Axin and affect its regulation of the Wnt and c-Jun N-terminal kinase signaling pathways.TBL1-TBLR1 and beta-catenin recruit each other to Wnt target-gene promoter for transcription activation and oncogenesisCaprin-2 enhances canonical Wnt signaling through regulating LRP5/6 phosphorylationDirect inhibition of GSK3beta by the phosphorylated cytoplasmic domain of LRP6 in Wnt/beta-catenin signalingWnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylationA novel mechanism for Wnt activation of canonical signaling through the LRP6 receptorMutations in AXIN2 cause familial tooth agenesis and predispose to colorectal cancerThe pseudoreceptor BMP and activin membrane-bound inhibitor positively modulates Wnt/beta-catenin signalingRegulation of Wnt/LRP signaling by distinct domains of Dickkopf proteins.Low-density lipoprotein receptor-related protein 5 (LRP5) is essential for normal cholesterol metabolism and glucose-induced insulin secretionA mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass traitA model for familial exudative vitreoretinopathy caused by LPR5 mutationsWnt/beta-catenin signaling: components, mechanisms, and diseasesWnt signal transduction pathwaysSUMOylation target sites at the C terminus protect Axin from ubiquitination and confer protein stabilityWnt signaling: the good and the badThe links between axin and carcinogenesisA nuclear function for armadillo/beta-cateninWnt/Wingless signaling through beta-catenin requires the function of both LRP/Arrow and frizzled classes of receptorsWnt signaling in breast cancer: have we come full circle?The WntsXenopus frizzled-4S, a splicing variant of Xfz4 is a context-dependent activator and inhibitor of Wnt/beta-catenin signaling.
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P2860
Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway
description
2001 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2001
@ast
im April 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2001/04/01)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/04/01)
@nl
наукова стаття, опублікована у квітні 2001
@uk
مقالة علمية (نشرت في أبريل 2001)
@ar
name
Low-density lipoprotein recept ...... anonical Wnt signaling pathway
@ast
Low-density lipoprotein recept ...... anonical Wnt signaling pathway
@en
Low-density lipoprotein recept ...... anonical Wnt signaling pathway
@nl
type
label
Low-density lipoprotein recept ...... anonical Wnt signaling pathway
@ast
Low-density lipoprotein recept ...... anonical Wnt signaling pathway
@en
Low-density lipoprotein recept ...... anonical Wnt signaling pathway
@nl
prefLabel
Low-density lipoprotein recept ...... anonical Wnt signaling pathway
@ast
Low-density lipoprotein recept ...... anonical Wnt signaling pathway
@en
Low-density lipoprotein recept ...... anonical Wnt signaling pathway
@nl
P2093
P921
P3181
P1433
P1476
Low-density lipoprotein recept ...... anonical Wnt signaling pathway
@en
P2093
D. Kimelman
G. H. Farr
P304
P3181
P356
10.1016/S1097-2765(01)00224-6
P407
P577
2001-04-01T00:00:00Z